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Database: UniProt/TrEMBL
Entry: F5YAI6_TREAZ
LinkDB: F5YAI6_TREAZ
Original site: F5YAI6_TREAZ 
ID   F5YAI6_TREAZ            Unreviewed;       604 AA.
AC   F5YAI6;
DT   27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT   27-JUL-2011, sequence version 1.
DT   11-JUN-2014, entry version 21.
DE   RecName: Full=L-fucose isomerase;
DE            Short=FucIase;
DE            EC=5.3.1.25;
DE   AltName: Full=6-deoxy-L-galactose isomerase;
GN   Name=fucI; OrderedLocusNames=TREAZ_3084;
OS   Treponema azotonutricium (strain ATCC BAA-888 / DSM 13862 / ZAS-9).
OC   Bacteria; Spirochaetes; Spirochaetales; Spirochaetaceae; Treponema.
OX   NCBI_TaxID=545695;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-888 / DSM 13862 / ZAS-9;
RA   Tetu S.G., Matson E., Ren Q., Seshadri R., Elbourne L., Hassan K.A.,
RA   Durkin A., Radune D., Mohamoud Y., Shay R., Jin S., Zhang X.,
RA   Lucey K., Ballor N.R., Ottesen E., Rosenthal R., Allen A.,
RA   Leadbetter J.R., Paulsen I.T.;
RT   "Complete sequence of Treponema azotonutricium strain ZAS-9.";
RL   Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Converts the aldose L-fucose into the corresponding
CC       ketose L-fuculose (By similarity).
CC   -!- CATALYTIC ACTIVITY: L-fucopyranose = L-fuculose.
CC   -!- COFACTOR: Manganese (By similarity).
CC   -!- PATHWAY: Carbohydrate degradation; L-fucose degradation; L-
CC       lactaldehyde and glycerone phosphate from L-fucose: step 1/3.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the L-fucose isomerase family.
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DR   EMBL; CP001841; AEF81807.1; -; Genomic_DNA.
DR   RefSeq; YP_004528369.1; NC_015577.1.
DR   EnsemblBacteria; AEF81807; AEF81807; TREAZ_3084.
DR   GeneID; 10677524; -.
DR   KEGG; taz:TREAZ_3084; -.
DR   KO; K01818; -.
DR   OMA; KEGQDYR; -.
DR   BioCyc; TAZO545695:GHPL-2919-MONOMER; -.
DR   UniPathway; UPA00563; UER00624.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008736; F:L-fucose isomerase activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0030145; F:manganese ion binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0042355; P:L-fucose catabolic process; IEA:UniProtKB-HAMAP.
DR   Gene3D; 3.20.14.10; -; 1.
DR   Gene3D; 3.40.275.10; -; 1.
DR   Gene3D; 3.40.50.1070; -; 1.
DR   HAMAP; MF_01254; Fucose_iso; 1.
DR   InterPro; IPR004216; Fuc/Ara_isomerase_C.
DR   InterPro; IPR015888; Fuc_isomerase_C.
DR   InterPro; IPR012888; Fucose_iso_N1.
DR   InterPro; IPR005763; Fucose_isomerase.
DR   InterPro; IPR009015; Fucose_isomerase_N/cen.
DR   InterPro; IPR012889; Fucose_isomerase_N2.
DR   Pfam; PF02952; Fucose_iso_C; 1.
DR   Pfam; PF07881; Fucose_iso_N1; 1.
DR   Pfam; PF07882; Fucose_iso_N2; 1.
DR   SUPFAM; SSF50443; SSF50443; 1.
DR   SUPFAM; SSF53743; SSF53743; 1.
DR   TIGRFAMs; TIGR01089; fucI; 1.
PE   3: Inferred from homology;
KW   Carbohydrate metabolism; Complete proteome; Cytoplasm;
KW   Fucose metabolism; Isomerase; Manganese; Metal-binding.
FT   ACT_SITE    352    352       Proton acceptor (By similarity){EA2}.
FT   ACT_SITE    376    376       Proton acceptor (By similarity){EA2}.
FT   METAL       352    352       Manganese (By similarity){EA2}.
FT   METAL       376    376       Manganese (By similarity){EA2}.
FT   METAL       542    542       Manganese (By similarity){EA2}.
SQ   SEQUENCE   604 AA;  66453 MW;  D7CC05D6813E1918 CRC64;
     MADLSSLKVT APVNRYRGAL PKIGIRPTID GRRRGVRESL EEPTMNMAKA AAKLISENLR
     HPNGQPIECV IADSCIGGVA EAAACQDKFS RENVGVTLTV TPCWCYGSET MDMDPATIKA
     VWGFNGTDRP GAVYLAAVLA AHSQKGLPAF GIYGRDVMDM ADITKVPQDV QDKILRFAKA
     ALAAVWMRGK SYLSIGSVAM GIAGSISNAD FFQEYLGMRN EYVDMSELVR RFDEKIYSDA
     EYKRALEWVK KNCKEGPDNN PPKEQHSRRR KDEVWKTVVK MAIIVRDLMI GNPDLKRKGL
     IEESLGHNAI LAGFQGQRQW TDHFPNGDFM EVILNSSFDW NGIRSPYVVA TENDGLNGVS
     MLFGYLLTGC AQVFADVRTY WSPDAIQRVT GWKPEGLAAN GLIHLINSGS AALDGIGKQK
     INGKPAWKPF WEITPEEAGA CLDSVSWRYG SLGYFRGGGY SSDFLSEGGM PVTMTRLNLV
     KGLGPVLQIA EGHTASVPEN VHDKLDARTD PTWPTTWFAP RITGEGPFKD VYTVMAKWGA
     NHGAVSYGHI GADLITLASI LRIPVCMHNV ELDKIYRPSY WNSFGMDAES ADYRACDALG
     PLFK
//
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