ID F6AFL5_PSEF1 Unreviewed; 284 AA.
AC F6AFL5;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 29-MAY-2013, entry version 13.
DE RecName: Full=Shikimate dehydrogenase;
DE EC=1.1.1.25;
GN Name=aroE; OrderedLocusNames=Psefu_2606;
OS Pseudomonas fulva (strain 12-X).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=743720;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=12-X;
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Mikhailova N., Pagani I., Davenport K., Han C., Tapia R.,
RA Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Lcollab F.I.,
RA Woyke T.;
RT "Complete sequence of Pseudomonas fulva 12-X.";
RL Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY: Shikimate + NADP(+) = 3-dehydroshikimate +
CC NADPH.
CC -!- PATHWAY: Metabolic intermediate biosynthesis; chorismate
CC biosynthesis; chorismate from D-erythrose 4-phosphate and
CC phosphoenolpyruvate: step 4/7.
CC -!- SIMILARITY: Belongs to the shikimate dehydrogenase family.
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DR EMBL; CP002727; AEF22571.1; -; Genomic_DNA.
DR RefSeq; YP_004474665.1; NC_015556.1.
DR EnsemblBacteria; AEF22571; AEF22571; Psefu_2606.
DR GeneID; 10654905; -.
DR KEGG; pfv:Psefu_2606; -.
DR KO; K00014; -.
DR OMA; HEHEGDA; -.
DR BioCyc; PFUL743720:GHQV-2648-MONOMER; -.
DR UniPathway; UPA00053; UER00087.
DR GO; GO:0004764; F:shikimate 3-dehydrogenase (NADP+) activity; IEA:HAMAP.
DR GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:HAMAP.
DR GO; GO:0009423; P:chorismate biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.40.50.720; -; 1.
DR HAMAP; MF_00222; Shikimate_DH_AroE; 1; -.
DR InterPro; IPR016040; NAD(P)-bd_dom.
DR InterPro; IPR013708; Shikimate_DH-bd_N.
DR InterPro; IPR022893; Shikimate_quinate_DH.
DR InterPro; IPR006151; Shikm_DH/Glu-tRNA_Rdtase.
DR Pfam; PF01488; Shikimate_DH; 1.
DR Pfam; PF08501; Shikimate_dh_N; 1.
PE 3: Inferred from homology;
KW Amino-acid biosynthesis; Aromatic amino acid biosynthesis;
KW Complete proteome; NADP; Oxidoreductase.
FT NP_BIND 135 139 NADP (By similarity).
FT ACT_SITE 75 75 Proton acceptor (By similarity).
SQ SEQUENCE 284 AA; 30262 MW; B627745485847348 CRC64;
MTSSKSILAG LIGAGIQASR TPAMHEHEGD AQGIRYLYRL IDLDQLKLDT SALPDLLSAA
ERMSFTGLNI TFPCKQAIIP LLDELSDEAR GIGAVNTVVF KDGKRIGHNT DCLGFSEGFK
RGLGDVARRR VVQMGAGGAG AAVAHALLSE GVEQLSIFDV EPERAQALAS NLNEHFGSPR
AQAGGDLSSA TAAADGLVNT TPMGMAKLPG MPVPKALLRK ELWVAEIVYF PLETELLREA
RAIGCRTLDG GNMAVFQAVK AFELFSDAQA DAQRMLDHFH SMNG
//
