ID   F8C2T5_THESO            Unreviewed;       392 AA.
AC   F8C2T5;
DT   21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT   21-SEP-2011, sequence version 1.
DT   03-APR-2013, entry version 12.
DE   SubName: Full=Thymidylate kinase;
GN   OrderedLocusNames=TOPB45_0197;
OS   Thermodesulfobacterium sp. (strain OPB45).
OC   Bacteria; Thermodesulfobacteria; Thermodesulfobacteriales;
OC   Thermodesulfobacteriaceae; Thermodesulfobacterium.
OX   NCBI_TaxID=795359;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OPB45;
RA   Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA   Peters L., Mikhailova N., Davenport K., Detter J.C., Han C., Tapia R.,
RA   Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I.,
RA   Hamilton-Brehm S., Elkins J., Woyke T.;
RT   "Complete sequence of Thermodesulfobacterium sp. OPB45.";
RL   Submitted (JUN-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: ATP + dTMP = ADP + dTDP.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; CP002829; AEH22312.1; -; Genomic_DNA.
DR   RefSeq; YP_004627240.1; NC_015682.1.
DR   EnsemblBacteria; AEH22312; AEH22312; TOPB45_0197.
DR   GeneID; 10838739; -.
DR   KEGG; top:TOPB45_0197; -.
DR   KO; K00943; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
DR   GO; GO:0019204; F:nucleotide phosphatase activity; IEA:InterPro.
DR   GO; GO:0004798; F:thymidylate kinase activity; IEA:InterPro.
DR   GO; GO:0006233; P:dTDP biosynthetic process; IEA:InterPro.
DR   HAMAP; MF_00165; Thymidylate_kinase; 1; -.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR004948; Nuc-triphosphatase_THEP1.
DR   InterPro; IPR018095; Thymidylate_kin_CS.
DR   InterPro; IPR018094; Thymidylate_kinase.
DR   PANTHER; PTHR10344; PTHR10344; 1.
DR   Pfam; PF03266; NTPase_1; 1.
DR   SMART; SM00382; AAA; 2.
DR   TIGRFAMs; TIGR00041; DTMP_kinase; 1.
DR   PROSITE; PS01331; THYMIDYLATE_KINASE; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Kinase; Nucleotide biosynthesis;
KW   Nucleotide-binding; Transferase.
SQ   SEQUENCE   392 AA;  45622 MW;  570B7192C968DC95 CRC64;
     MFLNSPRKKF FIFGAPGVGK TTLVKYLFEF LKNNLSSFNF SGFITTEIRE GFERKGFKIK
     VLNSDTESIL AIRKDLIDPK EIKDKPFVGK YIVNIENLEK VVEDLEKEFG KENVFFLIDE
     IGKMEILSLK FRNFIEKLLF SSRYLLATVG KGEDPFLKKV RDYEPAFLCE VTKENRDFLK
     NRLKFEFLRK GKLIAIEGID GAGKTTFAKA LFETLKKRGI NCIFSCEPTS GPFGEKIKSA
     LIKKIKKESN PQDLKLLFLK DRKWHVENII IPALEAQKWI ILDRYYPSTL AYQSSQGLSL
     KELLIENETI APIPDLVIYL DLPLEIAFKR IGNREKKLTI FEKREFLERV METYKKCLKL
     FNYLIIDATK PIEENLEYLL KFLDSKFKCP LS
//