ID F8FU69_PSEPU Unreviewed; 310 AA.
AC F8FU69;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 03-APR-2013, entry version 13.
DE RecName: Full=Methionyl-tRNA formyltransferase;
DE EC=2.1.2.9;
GN Name=fmt; ORFNames=PPS_0030;
OS Pseudomonas putida S16.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=1042876;
RN [1]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=S16;
RX PubMed=21914868; DOI=10.1128/JB.05663-11;
RA Yu H., Tang H., Wang L., Yao Y., Wu G., Xu P.;
RT "Complete Genome Sequence of the Nicotine-Degrading Pseudomonas putida
RT Strain S16.";
RL J. Bacteriol. 193:5541-5542(2011).
CC -!- FUNCTION: Modifies the free amino group of the aminoacyl moiety of
CC methionyl-tRNA(fMet). The formyl group appears to play a dual role
CC in the initiator identity of N-formylmethionyl-tRNA by: (I)
CC promoting its recognition by IF2 and (II) impairing its binding to
CC EFTu-GTP (By similarity).
CC -!- CATALYTIC ACTIVITY: 10-formyltetrahydrofolate + L-methionyl-
CC tRNA(fMet) = tetrahydrofolate + N-formylmethionyl-tRNA(fMet).
CC -!- SIMILARITY: Belongs to the fmt family.
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DR EMBL; CP002870; AEJ10619.1; -; Genomic_DNA.
DR RefSeq; YP_004699499.1; NC_015733.1.
DR EnsemblBacteria; AEJ10619; AEJ10619; PPS_0030.
DR GeneID; 10935702; -.
DR KEGG; ppt:PPS_0030; -.
DR KO; K00604; -.
DR BioCyc; PPUT1042876:GH0R-30-MONOMER; -.
DR GO; GO:0004479; F:methionyl-tRNA formyltransferase activity; IEA:HAMAP.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0006413; P:translational initiation; IEA:GOC.
DR Gene3D; 3.10.25.10; -; 1.
DR Gene3D; 3.40.50.170; -; 1.
DR HAMAP; MF_00182; Formyl_trans; 1; -.
DR InterPro; IPR005794; Fmt.
DR InterPro; IPR005793; Formyl_trans_C.
DR InterPro; IPR002376; Formyl_transf_N.
DR InterPro; IPR011034; Formyl_transferase_C-like.
DR InterPro; IPR001555; GART_AS.
DR InterPro; IPR015518; Met_tRNA_Form_TA-like.
DR PANTHER; PTHR11138; PTHR11138; 1.
DR Pfam; PF02911; Formyl_trans_C; 1.
DR Pfam; PF00551; Formyl_trans_N; 1.
DR SUPFAM; SSF50486; FMT_C_like; 1.
DR SUPFAM; SSF53328; formyl_transf; 1.
DR TIGRFAMs; TIGR00460; fmt; 1.
DR PROSITE; PS00373; GART; 1.
PE 3: Inferred from homology;
KW Methyltransferase; Protein biosynthesis; Transferase.
FT REGION 109 112 Tetrahydrofolate (THF) binding (By
FT similarity).
SQ SEQUENCE 310 AA; 32926 MW; B7242087AE8C26EA CRC64;
MRIVFAGTPE FAAEHLKALL DSPYEIVAVY TQPDRPAGRG QKLMPSPVKQ LAVAHDIPVF
QPPTLRNAEA QAELAALKPD LMVVVAYGLI LPQVVLDIPR LGCINSHASL LPRWRGAAPI
QRAVEAGDAE SGVTVMRMEA GLDTGPMLLK VVTPISAEDT GGSLHDRLAE MGPPAVVQAI
AGLADGSLQG EVQDDALATY AHKLNKDEAR IDWSRPAVEL ERLIRAFNPW PVCHSTLDGE
SVKVLAANLS TATGTPGEIL SASKDGLVVA CGDQALSLTR LQLPGGKALN FSDLFNSRRE
KFASGKVLGQ
//
