GenomeNet

Database: UniProt/TrEMBL
Entry: F8H016_PSEST
LinkDB: F8H016_PSEST
Original site: F8H016_PSEST 
ID   F8H016_PSEST            Unreviewed;       742 AA.
AC   F8H016;
DT   21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT   21-SEP-2011, sequence version 1.
DT   22-NOV-2017, entry version 34.
DE   SubName: Full=Isocitrate dehydrogenase {ECO:0000313|EMBL:AEJ05468.1};
GN   Name=icd {ECO:0000313|EMBL:AEJ05468.1};
GN   OrderedLocusNames=PSTAB_2187 {ECO:0000313|EMBL:AEJ05468.1};
OS   Pseudomonas stutzeri (Pseudomonas perfectomarina).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=316 {ECO:0000313|EMBL:AEJ05468.1, ECO:0000313|Proteomes:UP000008932};
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ATCC 17588;
RA   Yan Y., Chen M., Lu W., Zhang W., Ping S., Lin M.;
RT   "Complete Genome Sequence of Pseudomonas stutzeri Strain CGMCC
RT   1.1803.";
RL   Submitted (JUN-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Proteomes:UP000008932}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 17588 / DSM 5190 / CCUG 11256 / JCM 5965 / LMG 11199 /
RC   NCIMB 11358 / Stanier 221 {ECO:0000313|Proteomes:UP000008932};
RA   Yan Y., Chen M., Lu W., Zhang W., Ping S., Lin M.;
RT   "Complete genome sequence of Pseudomonas stutzeri strain CGMCC
RT   1.1803.";
RL   Submitted (JUN-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|PIRSR:PIRSR009407-3};
CC       Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC         Evidence={ECO:0000256|PIRSR:PIRSR009407-3};
CC       Note=Binds 1 Mg(2+) or Mn(2+) ion per subunit.
CC       {ECO:0000256|PIRSR:PIRSR009407-3};
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; CP002881; AEJ05468.1; -; Genomic_DNA.
DR   RefSeq; WP_013982944.1; NC_015740.1.
DR   EnsemblBacteria; AEJ05468; AEJ05468; PSTAB_2187.
DR   GeneID; 28546807; -.
DR   KEGG; psz:PSTAB_2187; -.
DR   KO; K00031; -.
DR   OrthoDB; POG091H0B3N; -.
DR   Proteomes; UP000008932; Chromosome.
DR   GO; GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR   InterPro; IPR004436; Isocitrate_DH_NADP_mono.
DR   PANTHER; PTHR36999; PTHR36999; 1.
DR   Pfam; PF03971; IDH; 1.
DR   PIRSF; PIRSF009407; IDH_monmr; 1.
DR   TIGRFAMs; TIGR00178; monomer_idh; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000008932};
KW   Magnesium {ECO:0000256|PIRSR:PIRSR009407-3};
KW   Metal-binding {ECO:0000256|PIRSR:PIRSR009407-3}.
FT   REGION      133    140       Substrate binding. {ECO:0000256|PIRSR:
FT                                PIRSR009407-2}.
FT   METAL       350    350       Magnesium or manganese.
FT                                {ECO:0000256|PIRSR:PIRSR009407-3}.
FT   METAL       548    548       Magnesium or manganese.
FT                                {ECO:0000256|PIRSR:PIRSR009407-3}.
FT   METAL       552    552       Magnesium or manganese.
FT                                {ECO:0000256|PIRSR:PIRSR009407-3}.
FT   BINDING     146    146       Substrate. {ECO:0000256|PIRSR:
FT                                PIRSR009407-2}.
FT   BINDING     547    547       Substrate. {ECO:0000256|PIRSR:
FT                                PIRSR009407-2}.
FT   SITE        255    255       Critical for catalysis.
FT                                {ECO:0000256|PIRSR:PIRSR009407-1}.
FT   SITE        420    420       Critical for catalysis.
FT                                {ECO:0000256|PIRSR:PIRSR009407-1}.
SQ   SEQUENCE   742 AA;  81713 MW;  22A4AC049D98563C CRC64;
     MSTPSKIIYT FTDEAPALAT YSLLPIVEAF AASADISVET RDISLAGRIL ASFADQLDAD
     KKVEDDLAKL AELTNQPDAN IIKLPNISAS VPQLKAAIAE LQALGYNIPN YPEDPQTDAE
     KDARARYSKV LGSAVNPVLR EGNSDRRAPA AVKAYARKHP HSMGKWSKAS QSHADYMRGG
     DFFSSEQSIT MEKAGDVRIE FVGKDGKVEV KKQLALQEGE VLDGMFMSCK KLRAFFEDTL
     QDCKETGIMW SLHVKATMMK ISHPIVFGHA VSVYYKDVFD KYGDLFKELG VNPNNGISSV
     YDKIKSLPAS QQEEILHDIH EVYSHRPEMA MVDSVKGITN LHIPSDVIVD ASMPAMIRNS
     GQMWGKDGKQ KDTKAVMPES TYARIYQEMI NFCKTNGAFD PVTMGSVPNV GLMAQKAEEY
     GSHDKTFEMH ADGTMRVVLA DGTVLMQHEV EKGDIWRACQ TKDAPIRDWV KLAVTRARQS
     NTPAVFWLDP ERAHDMQLQK KVETYLQEHD LSGLDIRIMG YNEAIRLSME RMIRGKDTIS
     VTGNVLRDYL TDLFPIMELG TSAKMLSIVP LMAGGGMYET GAGGSAPKHV QQLVEENYLR
     WDSLGEFLAL AVSLEETGIK TGNGKAKILG KTLDQATGKL LDNNKSPARK VGQIDNRGSH
     FYLALYWAQA LAAQDEDAEL KAHFTPLAKT LTEQEAAIVA ELAAVQGKPV DIGGYYRSNP
     ELTSKVMRPS ATFNAALAAL NA
//
DBGET integrated database retrieval system