GenomeNet

Database: UniProt/TrEMBL
Entry: F8LP28_STRE8
LinkDB: F8LP28_STRE8
Original site: F8LP28_STRE8 
ID   F8LP28_STRE8            Unreviewed;       940 AA.
AC   F8LP28;
DT   21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT   21-SEP-2011, sequence version 1.
DT   07-JUN-2017, entry version 39.
DE   RecName: Full=Phosphoenolpyruvate carboxylase {ECO:0000256|HAMAP-Rule:MF_00595, ECO:0000256|SAAS:SAAS00635171};
DE            Short=PEPC {ECO:0000256|HAMAP-Rule:MF_00595};
DE            Short=PEPCase {ECO:0000256|HAMAP-Rule:MF_00595};
DE            EC=4.1.1.31 {ECO:0000256|HAMAP-Rule:MF_00595, ECO:0000256|SAAS:SAAS00635171};
GN   Name=ppc {ECO:0000256|HAMAP-Rule:MF_00595,
GN   ECO:0000313|EMBL:CCB95098.1};
GN   OrderedLocusNames=SALIVA_0772 {ECO:0000313|EMBL:CCB95098.1};
OS   Streptococcus salivarius (strain JIM8777).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=347253 {ECO:0000313|EMBL:CCB95098.1, ECO:0000313|Proteomes:UP000000507};
RN   [1] {ECO:0000313|EMBL:CCB95098.1, ECO:0000313|Proteomes:UP000000507}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JIM8777 {ECO:0000313|EMBL:CCB95098.1,
RC   ECO:0000313|Proteomes:UP000000507};
RX   PubMed=21742871; DOI=10.1128/JB.05390-11;
RA   Guedon E., Delorme C., Pons N., Cruaud C., Loux V., Couloux A.,
RA   Gautier C., Sanchez N., Layec S., Galleron N., Almeida M.,
RA   van de Guchte M., Kennedy S.P., Ehrlich S.D., Gibrat J.F., Wincker P.,
RA   Renault P.;
RT   "Complete genome sequence of the commensal Streptococcus salivarius
RT   strain JIM8777.";
RL   J. Bacteriol. 193:5024-5025(2011).
CC   -!- FUNCTION: Forms oxaloacetate, a four-carbon dicarboxylic acid
CC       source for the tricarboxylic acid cycle. {ECO:0000256|HAMAP-
CC       Rule:MF_00595, ECO:0000256|SAAS:SAAS00730191}.
CC   -!- CATALYTIC ACTIVITY: Phosphate + oxaloacetate = H(2)O +
CC       phosphoenolpyruvate + HCO(3)(-). {ECO:0000256|HAMAP-Rule:MF_00595,
CC       ECO:0000256|SAAS:SAAS00635165}.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000256|HAMAP-
CC         Rule:MF_00595, ECO:0000256|SAAS:SAAS00635164};
CC   -!- SUBUNIT: Homotetramer. {ECO:0000256|HAMAP-Rule:MF_00595}.
CC   -!- SIMILARITY: Belongs to the PEPCase type 1 family.
CC       {ECO:0000256|HAMAP-Rule:MF_00595, ECO:0000256|SAAS:SAAS00635168}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; FR873482; CCB95098.1; -; Genomic_DNA.
DR   RefSeq; WP_014634244.1; NC_017595.1.
DR   EnsemblBacteria; CCB95098; CCB95098; SALIVA_0772.
DR   KEGG; stj:SALIVA_0772; -.
DR   PATRIC; fig|347253.5.peg.689; -.
DR   KO; K01595; -.
DR   OMA; PWVFGWT; -.
DR   Proteomes; UP000000507; Chromosome.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0008964; F:phosphoenolpyruvate carboxylase activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0015977; P:carbon fixation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006107; P:oxaloacetate metabolic process; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR   HAMAP; MF_00595; PEPcase_type1; 1.
DR   InterPro; IPR021135; PEP_COase.
DR   InterPro; IPR022805; PEP_COase_bac/pln-type.
DR   InterPro; IPR018129; PEP_COase_Lys_AS.
DR   InterPro; IPR033129; PEPCASE_His_AS.
DR   InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR   Pfam; PF00311; PEPcase; 1.
DR   PRINTS; PR00150; PEPCARBXLASE.
DR   SUPFAM; SSF51621; SSF51621; 2.
DR   PROSITE; PS00781; PEPCASE_1; 1.
DR   PROSITE; PS00393; PEPCASE_2; 1.
PE   3: Inferred from homology;
KW   Carbon dioxide fixation {ECO:0000256|HAMAP-Rule:MF_00595,
KW   ECO:0000256|SAAS:SAAS00635173};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000507};
KW   Lyase {ECO:0000256|HAMAP-Rule:MF_00595, ECO:0000256|SAAS:SAAS00635169,
KW   ECO:0000313|EMBL:CCB95098.1};
KW   Magnesium {ECO:0000256|HAMAP-Rule:MF_00595,
KW   ECO:0000256|SAAS:SAAS00635157};
KW   Pyruvate {ECO:0000313|EMBL:CCB95098.1}.
FT   ACT_SITE    138    138       {ECO:0000256|HAMAP-Rule:MF_00595,
FT                                ECO:0000256|PROSITE-ProRule:PRU10111}.
FT   ACT_SITE    603    603       {ECO:0000256|HAMAP-Rule:MF_00595,
FT                                ECO:0000256|PROSITE-ProRule:PRU10112}.
SQ   SEQUENCE   940 AA;  107026 MW;  5431B1295C223FFB CRC64;
     MAFNKLESSN NQEIISEEVG ILKELLDDAT RGMAGEQGLT TIQHLVELYD EGDYVALTQA
     ISEMTNDDMV VASRYFSLLP LLINISEDVD LAYEVNHKNN IDESYLGKLS ETFDVVAESD
     NARDILEHVN VVPVLTAHPT QVQRKTMLEL TNHIHELLRK HRDVKAGLIN KDKWYADLRR
     YVEIMMQTDI IREKKLKVKN EITNVMEYYN SSLIKAITNL SHEFKRLAVE KGIELDNPTP
     ITMGMWIGGD RDGNPFVTAE TLKLSATLQS EVILNYYIEK VDNLYRSFSL SSRLTEVSDT
     VAEMAKHSPD TSVYRENEPY RRAFSYIQSK LIQTLLFFKE GNFNKERVAK RLSENVRLGS
     ASTGEVVADY VQQRLSQSLQ AVSQQTTEFY ETADAFHDDL LAIKNSLLEN DDAVLISGDF
     EELLQAVEVF GFYLATIDMR QDSSVHEACV AELLKSANIV DNYSELTEVE KVAVLLKELQ
     EDPRTLSSTN VPKSETLEKE LAIFRTARLL KDYIGEDVIK QHIISHTESV SDMFELAILL
     KEVGLVDTER ARVQIVPLFE TIEDLENSND IMKQYLGYDI VKRWIKNSNN YQEIMLGYSD
     SNKDGGYLSS GWTLYKAQNE LTKIGEERGI KITFFHGRGG TVGRGGGPSY DAITSQPFGT
     IKDRIRLTEQ GEVIGNKYGN KDAAYYNLEM LVSAALDRMV TRQIADPDEL VDFREIMDGI
     VHDSNVIYRD LVFGNEHFYD YFFEASPIKE VSSLNIGSRP AARKTITEIS GLRAIPWVFS
     WSQNRIMFPG WYGVGSAFNR FIQAEEGNLE KLQHMFETWP FFRSLLSNVD MVLSKSDMNI
     AFHYAQLAES EEVRSVFNII LDEWQLTKDV ILAIEKHDGF LDESPSLKAS LDFRLPYFNV
     LNYIQIELIK RLRNNDLTDD EISLIHITIN GIATGLRNSG
//
DBGET integrated database retrieval system