ID F8M7K9_MYCA0 Unreviewed; 408 AA.
AC F8M7K9;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 03-APR-2013, entry version 13.
DE RecName: Full=Alanine racemase;
DE EC=5.1.1.1;
GN Name=alr; OrderedLocusNames=MAF_34370;
OS Mycobacterium africanum (strain GM041182).
OC Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC Corynebacterineae; Mycobacteriaceae; Mycobacterium;
OC Mycobacterium tuberculosis complex.
OX NCBI_TaxID=572418;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GM041182;
RA Bentley S.D., Comas I., Walker D., Smith N.H., Harris S.R.,
RA Thurston S., Gagneux S., Wood J., Antonio M., Quail M.A., Gehre F.,
RA Adegbola R.A., Parkhill J., De Jong B.C.;
RT "The genome of Mycobacterium africanum West African 2 reveals a
RT lineage-specific locus and features of genome erosion shared with
RT other members of the tuberculosis complex.";
RL Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY: L-alanine = D-alanine.
CC -!- COFACTOR: Pyridoxal phosphate (By similarity).
CC -!- PATHWAY: Amino-acid biosynthesis; D-alanine biosynthesis; D-
CC alanine from L-alanine: step 1/1.
CC -!- SIMILARITY: Belongs to the alanine racemase family.
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DR EMBL; FR878060; CCC28506.1; -; Genomic_DNA.
DR RefSeq; YP_004725070.1; NC_015758.1.
DR ProteinModelPortal; F8M7K9; -.
DR SMR; F8M7K9; 35-405.
DR EnsemblBacteria; CCC28506; CCC28506; MAF_34370.
DR GeneID; 10956665; -.
DR KEGG; maf:MAF_34370; -.
DR KO; K01775; -.
DR BioCyc; MAFR572418:GJCK-3460-MONOMER; -.
DR UniPathway; UPA00042; UER00497.
DR GO; GO:0008784; F:alanine racemase activity; IEA:EC.
DR GO; GO:0030632; P:D-alanine biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 2.40.37.10; -; 1.
DR HAMAP; MF_01201; Ala_racemase; 1; -.
DR InterPro; IPR000821; Ala_racemase.
DR InterPro; IPR009006; Ala_racemase/Decarboxylase_C.
DR InterPro; IPR011079; Ala_racemase_C.
DR InterPro; IPR001608; Ala_racemase_N.
DR InterPro; IPR020622; Ala_racemase_pyridoxalP-BS.
DR Pfam; PF00842; Ala_racemase_C; 1.
DR Pfam; PF01168; Ala_racemase_N; 1.
DR PRINTS; PR00992; ALARACEMASE.
DR SMART; SM01005; Ala_racemase_C; 1.
DR SUPFAM; SSF50621; Racem_decarbox_C; 1.
DR TIGRFAMs; TIGR00492; alr; 1.
DR PROSITE; PS00395; ALANINE_RACEMASE; 1.
PE 3: Inferred from homology;
KW Complete proteome; Isomerase; Pyridoxal phosphate.
SQ SEQUENCE 408 AA; 43388 MW; 44FECA297BA7C8E2 CRC64;
MKRFWENVGK PNDTTDGRGT TSLAMTPISQ TPGLLAEAMV DLGAIEHNVR VLREHAGHAQ
LMAVVKADGY GHGATRVAQT ALGAGAAELG VATVDEALAL RADGITAPVL AWLHPPGIDF
GPALLADVQV AVSSLRQLDE LLHAVRRTGR TATVTVKVDT GLNRNGVGPA QFPAMLTALR
QAMAEDAVRL RGLMSHMVYA DKPDDSINDV QAQRFTAFLA QAREQGVRFE VAHLSNSSAT
MARPDLTFDL VRPGIAVYGL SPVPALGDMG LVPAMTVKCA VALVKSIRAG EGVSYGHTWI
APRDTNLALL PIGYADGVFR SLGGRLEVLI NGRRCPGVGR ICMDQFMVDL GPGPLDVAEG
DEAILFGPGI RGEPTAQDWA DLVGTIHYEV VTSPRGRITR TYREAENR
//
