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Database: UniProt/TrEMBL
Entry: G0E6C8_ENTAK
LinkDB: G0E6C8_ENTAK
Original site: G0E6C8_ENTAK 
ID   G0E6C8_ENTAK            Unreviewed;       539 AA.
AC   G0E6C8;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   19-FEB-2014, entry version 18.
DE   RecName: Full=Phosphoenolpyruvate carboxykinase [ATP];
DE            Short=PCK;
DE            Short=PEP carboxykinase;
DE            Short=PEPCK;
DE            EC=4.1.1.49;
DE   AltName: Full=Phosphoenolpyruvate carboxylase;
GN   Name=pckA; OrderedLocusNames=EAE_05235;
OS   Enterobacter aerogenes (strain ATCC 13048 / DSM 30053 / JCM 1235 /
OS   KCTC 2190 / NBRC 13534 / NCIMB 10102 / NCTC 10006) (Aerobacter
OS   aerogenes).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Enterobacter.
OX   NCBI_TaxID=1028307;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 13048 / DSM 30053 / JCM 1235 / KCTC 2190 / NBRC 13534 /
RC   NCIMB 10102 / NCTC 10006;
RA   Shin S.H., Kim S., Kim J.Y., Yang K.-S., Seo J.-S.;
RT   "Complete sequence of Enterobacter aerogenes KCTC 2190.";
RL   Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in the gluconeogenesis. Catalyzes the
CC       conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP)
CC       through direct phosphoryl transfer between the nucleoside
CC       triphosphate and OAA (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP + oxaloacetate = ADP + phosphoenolpyruvate
CC       + CO(2).
CC   -!- COFACTOR: Binds 1 manganese ion per subunit (By similarity).
CC   -!- PATHWAY: Carbohydrate biosynthesis; gluconeogenesis.
CC   -!- SUBUNIT: Monomer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the phosphoenolpyruvate carboxykinase [ATP]
CC       family.
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DR   EMBL; CP002824; AEG95974.1; -; Genomic_DNA.
DR   RefSeq; YP_004591253.1; NC_015663.1.
DR   EnsemblBacteria; AEG95974; AEG95974; EAE_05235.
DR   GeneID; 10791220; -.
DR   KEGG; eae:EAE_05235; -.
DR   KO; K01610; -.
DR   OMA; RYAGEMK; -.
DR   BioCyc; EAER1028307:GHNA-1062-MONOMER; -.
DR   UniPathway; UPA00138; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004612; F:phosphoenolpyruvate carboxykinase (ATP) activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006094; P:gluconeogenesis; IEA:UniProtKB-HAMAP.
DR   Gene3D; 3.40.449.10; -; 1.
DR   Gene3D; 3.90.228.20; -; 2.
DR   HAMAP; MF_00453; PEPCK_ATP; 1.
DR   InterPro; IPR001272; PEP_carboxykinase_ATP.
DR   InterPro; IPR013035; PEP_carboxykinase_C.
DR   InterPro; IPR008210; PEP_carboxykinase_N.
DR   InterPro; IPR015994; PEPCK_ATP_CS.
DR   Pfam; PF01293; PEPCK_ATP; 1.
DR   PIRSF; PIRSF006294; PEP_crbxkin; 1.
DR   SUPFAM; SSF68923; SSF68923; 1.
DR   TIGRFAMs; TIGR00224; pckA; 1.
DR   PROSITE; PS00532; PEPCK_ATP; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; Decarboxylase;
KW   Gluconeogenesis; Kinase; Lyase; Manganese; Metal-binding;
KW   Nucleotide-binding; Pyruvate; Transferase.
FT   NP_BIND     247    255       ATP (By similarity).
FT   NP_BIND     448    449       ATP (By similarity).
FT   METAL       212    212       Manganese (By similarity).
FT   METAL       231    231       Manganese; via tele nitrogen (By
FT                                similarity).
FT   METAL       268    268       Manganese (By similarity).
FT   BINDING      64     64       Substrate (By similarity).
FT   BINDING     206    206       Substrate (By similarity).
FT   BINDING     212    212       ATP (By similarity).
FT   BINDING     212    212       Substrate (By similarity).
FT   BINDING     231    231       ATP (By similarity).
FT   BINDING     296    296       ATP (By similarity).
FT   BINDING     332    332       ATP (By similarity).
FT   BINDING     332    332       Substrate (By similarity).
FT   BINDING     454    454       ATP (By similarity).
SQ   SEQUENCE   539 AA;  59592 MW;  287D9C6BB34328A3 CRC64;
     MRVNSLTPQD LKAYGINDVQ EIVHNPSFDT LYQEELDPKL EGYERGVLTN LGAIAVDTGI
     FTGRSPKDKY IVRDDTTRDT VWWSDKGNGK NDNKPLSQET WQHLKGLVTH QLSGKRLFIV
     DAFCGANADT RLSVRFITEV AWQAHFVKNM FIRPSEEELA AFEPDFIVMN GAKCTNPQWK
     EQGLNSENFV AFNLTERIQL IGGTWYGGEM KKGMFSIMNY LLPLQGIASM HCSANVGEKG
     DVAVFFGLSG TGKTTLSTDP KRRLIGDDEH GWDDDGVFNF EGGCYAKTIK LSEANEPDIY
     HAIRRDALLE NVVVRADGTI DFDDGSKTEN TRVSYPIDHI ENIVKPVSKA GHATKVIFLT
     ADAFGVLPPV SRLTADQTQY HFLSGFTAKL AGTERGVTEP TPTFSACFGA AFLSLHPTQY
     AEVLVKRMQA SGAQAYLVNT GWNGTGKRIS IKDTRAIIDA ILDGSLDNAE TFTLPMFNLQ
     IPTELPGVDT HILDPRNTYG SPEQWQEKAD QLAKLFIENF EKYTDTPAGA ALVAAGPKR
//
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