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Database: UniProt/TrEMBL
Entry: G0REV3_HYPJQ
LinkDB: G0REV3_HYPJQ
Original site: G0REV3_HYPJQ 
ID   G0REV3_HYPJQ            Unreviewed;       960 AA.
AC   G0REV3;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   05-JUL-2017, entry version 36.
DE   RecName: Full=DNA ligase {ECO:0000256|RuleBase:RU000617};
DE            EC=6.5.1.1 {ECO:0000256|RuleBase:RU000617};
DE   Flags: Fragment;
GN   ORFNames=TRIREDRAFT_58509 {ECO:0000313|EMBL:EGR50407.1};
OS   Hypocrea jecorina (strain QM6a) (Trichoderma reesei).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
OC   Sordariomycetes; Hypocreomycetidae; Hypocreales; Hypocreaceae;
OC   Trichoderma.
OX   NCBI_TaxID=431241 {ECO:0000313|Proteomes:UP000008984};
RN   [1] {ECO:0000313|EMBL:EGR50407.1, ECO:0000313|Proteomes:UP000008984}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=QM6a {ECO:0000313|EMBL:EGR50407.1,
RC   ECO:0000313|Proteomes:UP000008984};
RX   PubMed=18454138; DOI=10.1038/nbt1403;
RA   Martinez D., Berka R.M., Henrissat B., Saloheimo M., Arvas M.,
RA   Baker S.E., Chapman J., Chertkov O., Coutinho P.M., Cullen D.,
RA   Danchin E.G., Grigoriev I.V., Harris P., Jackson M., Kubicek C.P.,
RA   Han C.S., Ho I., Larrondo L.F., de Leon A.L., Magnuson J.K.,
RA   Merino S., Misra M., Nelson B., Putnam N., Robbertse B., Salamov A.A.,
RA   Schmoll M., Terry A., Thayer N., Westerholm-Parvinen A., Schoch C.L.,
RA   Yao J., Barabote R., Nelson M.A., Detter C., Bruce D., Kuske C.R.,
RA   Xie G., Richardson P., Rokhsar D.S., Lucas S.M., Rubin E.M.,
RA   Dunn-Coleman N., Ward M., Brettin T.S.;
RT   "Genome sequencing and analysis of the biomass-degrading fungus
RT   Trichoderma reesei (syn. Hypocrea jecorina).";
RL   Nat. Biotechnol. 26:553-560(2008).
CC   -!- CATALYTIC ACTIVITY: ATP + (deoxyribonucleotide)(n)-3'-hydroxyl +
CC       5'-phospho-(deoxyribonucleotide)(m) = (deoxyribonucleotide)(n+m) +
CC       AMP + diphosphate. {ECO:0000256|RuleBase:RU000617}.
CC   -!- SIMILARITY: Belongs to the ATP-dependent DNA ligase family.
CC       {ECO:0000256|RuleBase:RU004196}.
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DR   EMBL; GL985060; EGR50407.1; -; Genomic_DNA.
DR   RefSeq; XP_006963892.1; XM_006963830.1.
DR   STRING; 51453.JGI58509; -.
DR   EnsemblFungi; EGR50407; EGR50407; TRIREDRAFT_58509.
DR   GeneID; 18486306; -.
DR   KEGG; tre:TRIREDRAFT_58509; -.
DR   EuPathDB; FungiDB:TRIREDRAFT_58509; -.
DR   KO; K10777; -.
DR   OrthoDB; EOG092C18KW; -.
DR   Proteomes; UP000008984; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003910; F:DNA ligase (ATP) activity; IEA:UniProtKB-EC.
DR   GO; GO:0071897; P:DNA biosynthetic process; IEA:InterPro.
DR   GO; GO:0051103; P:DNA ligation involved in DNA repair; IEA:InterPro.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   CDD; cd00027; BRCT; 2.
DR   Gene3D; 3.40.50.10190; -; 2.
DR   InterPro; IPR001357; BRCT_dom.
DR   InterPro; IPR000977; DNA_ligase_ATP-dep.
DR   InterPro; IPR012309; DNA_ligase_ATP-dep_C.
DR   InterPro; IPR012310; DNA_ligase_ATP-dep_cent.
DR   InterPro; IPR016059; DNA_ligase_ATP-dep_CS.
DR   InterPro; IPR012308; DNA_ligase_ATP-dep_N.
DR   InterPro; IPR021536; DNA_ligase_IV_dom.
DR   InterPro; IPR029710; LIG4.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   PANTHER; PTHR10459:SF84; PTHR10459:SF84; 1.
DR   Pfam; PF16589; BRCT_2; 1.
DR   Pfam; PF04679; DNA_ligase_A_C; 1.
DR   Pfam; PF01068; DNA_ligase_A_M; 1.
DR   Pfam; PF04675; DNA_ligase_A_N; 1.
DR   Pfam; PF11411; DNA_ligase_IV; 1.
DR   SMART; SM00292; BRCT; 2.
DR   SUPFAM; SSF117018; SSF117018; 1.
DR   SUPFAM; SSF50249; SSF50249; 1.
DR   SUPFAM; SSF52113; SSF52113; 2.
DR   TIGRFAMs; TIGR00574; dnl1; 1.
DR   PROSITE; PS50172; BRCT; 2.
DR   PROSITE; PS00697; DNA_LIGASE_A1; 1.
DR   PROSITE; PS50160; DNA_LIGASE_A3; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|RuleBase:RU000617};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000008984};
KW   DNA damage {ECO:0000256|RuleBase:RU000617};
KW   DNA recombination {ECO:0000256|RuleBase:RU000617};
KW   DNA repair {ECO:0000256|RuleBase:RU000617};
KW   DNA replication {ECO:0000256|RuleBase:RU000617};
KW   Ligase {ECO:0000256|RuleBase:RU000617, ECO:0000313|EMBL:EGR50407.1};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU000617};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008984}.
FT   DOMAIN      402    527       DNA_LIGASE_A3. {ECO:0000259|PROSITE:
FT                                PS50160}.
FT   DOMAIN      695    777       BRCT. {ECO:0000259|PROSITE:PS50172}.
FT   DOMAIN      858    960       BRCT. {ECO:0000259|PROSITE:PS50172}.
FT   COILED      644    671       {ECO:0000256|SAM:Coils}.
FT   NON_TER       1      1       {ECO:0000313|EMBL:EGR50407.1}.
SQ   SEQUENCE   960 AA;  110519 MW;  FFB00BD3DDAC5FFC CRC64;
     RYPNKPRNHS KTLKFAELFK ELFNPLNDNK KQPSGPSIPA SKRGPHGLTK LSPQEQRRHI
     IERFITRWRK EVGNDFYPAL RLILPDKDRD RGVYGLKENA IGKLLVKLMK IDKNSEDGYN
     LLHWKLPGQT TGARLAGDFA GRCFEVISKR PMRTQVGDMT IAEVNHQLDK LAASSGEAEN
     LRIFETFYNR MNAEELMWLI RIILKQMKVG ATEKTFLYLW HPDAEALFSV SSSLRRVCWE
     LYDPEFRLEQ DEAGIAVMQC FQPQLAQFQM PASFQKMIEL LRPTEDDAEF WIEEKLDGER
     MQMHMMEDPN HPGGRRFRWW SRKAKDYTYL YGDGLLDENS SLTRHLKNAF APGVRNLILD
     GEMITWDMGV DKIVPFGTLK SAAIAEQSNK SESNAAGHRP LFRVFDILYL NDKQLTQYTL
     RDRRNALQKA IRPVHRRLEI HEYTPATSAD AIEPLLREVV ANASEGLVLK NPRSMYRLNS
     RNDDWLKVKP EYMSEFGESL DCVIIGGYYG SGRRGGMLSS FLCGLRVSPN HIQAGANPEK
     CFSFFKVGGG FRTEDYAEIR HRTDGKWMEW DPKNPPSEYI ELGGGEAKQY ERPDMWIRPK
     DSVVVSVKAA SVGPSDQFAR GFTLRFPRFR RLRLDRSWDT ALSLEEFQEL KQRVESELKA
     TEMTVEDRRR RNPKRIKKEL VIAGDDTAPP LFEGNKTKLF EGLEFCVLSE SLKPYKKTKP
     QLEAIIKENG GSISQRAAAG TRMILIADKR VVKVASLIKD GNADIIRPRW IRDCLEQPDG
     GFLLPYEPGR HIFHATDALA EVAAQNTDRY GDSYARDVDV EELRELMRDM PKLEDRQTFD
     KMLFLEQLEQ HGKDVGSLRN FMFSRCRVLL YLVDGAKESA RDKWERYVRY GGGSVSRDAD
     DDSVTHIVVL GDDVMEVGDV GDKLRSKLSS RRKMPRLVSE GWVEESWRER TLLDEERYAV
//
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