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Database: UniProt/TrEMBL
Entry: G0RU80_HYPJQ
LinkDB: G0RU80_HYPJQ
Original site: G0RU80_HYPJQ 
ID   G0RU80_HYPJQ            Unreviewed;       302 AA.
AC   G0RU80;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   05-JUL-2017, entry version 33.
DE   SubName: Full=Histone H3 methyltransferase {ECO:0000313|EMBL:EGR45341.1};
GN   ORFNames=TRIREDRAFT_111216 {ECO:0000313|EMBL:EGR45341.1};
OS   Hypocrea jecorina (strain QM6a) (Trichoderma reesei).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
OC   Sordariomycetes; Hypocreomycetidae; Hypocreales; Hypocreaceae;
OC   Trichoderma.
OX   NCBI_TaxID=431241 {ECO:0000313|Proteomes:UP000008984};
RN   [1] {ECO:0000313|EMBL:EGR45341.1, ECO:0000313|Proteomes:UP000008984}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=QM6a {ECO:0000313|EMBL:EGR45341.1,
RC   ECO:0000313|Proteomes:UP000008984};
RX   PubMed=18454138; DOI=10.1038/nbt1403;
RA   Martinez D., Berka R.M., Henrissat B., Saloheimo M., Arvas M.,
RA   Baker S.E., Chapman J., Chertkov O., Coutinho P.M., Cullen D.,
RA   Danchin E.G., Grigoriev I.V., Harris P., Jackson M., Kubicek C.P.,
RA   Han C.S., Ho I., Larrondo L.F., de Leon A.L., Magnuson J.K.,
RA   Merino S., Misra M., Nelson B., Putnam N., Robbertse B., Salamov A.A.,
RA   Schmoll M., Terry A., Thayer N., Westerholm-Parvinen A., Schoch C.L.,
RA   Yao J., Barabote R., Nelson M.A., Detter C., Bruce D., Kuske C.R.,
RA   Xie G., Richardson P., Rokhsar D.S., Lucas S.M., Rubin E.M.,
RA   Dunn-Coleman N., Ward M., Brettin T.S.;
RT   "Genome sequencing and analysis of the biomass-degrading fungus
RT   Trichoderma reesei (syn. Hypocrea jecorina).";
RL   Nat. Biotechnol. 26:553-560(2008).
CC   -!- CATALYTIC ACTIVITY: S-adenosyl-L-methionine + L-lysine-[histone] =
CC       S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].
CC       {ECO:0000256|SAAS:SAAS00591578}.
CC   -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|SAAS:SAAS00563877}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|SAAS:SAAS00574581}.
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DR   EMBL; GL985080; EGR45341.1; -; Genomic_DNA.
DR   RefSeq; XP_006968782.1; XM_006968720.1.
DR   STRING; 51453.JGI111216; -.
DR   EnsemblFungi; EGR45341; EGR45341; TRIREDRAFT_111216.
DR   GeneID; 18482291; -.
DR   KEGG; tre:TRIREDRAFT_111216; -.
DR   EuPathDB; FungiDB:TRIREDRAFT_111216; -.
DR   KO; K11419; -.
DR   OrthoDB; EOG092C2EWO; -.
DR   Proteomes; UP000008984; Unassembled WGS sequence.
DR   GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   InterPro; IPR003616; Post-SET_dom.
DR   InterPro; IPR007728; Pre-SET_dom.
DR   InterPro; IPR001214; SET_dom.
DR   Pfam; PF05033; Pre-SET; 1.
DR   Pfam; PF00856; SET; 1.
DR   SMART; SM00468; PreSET; 1.
DR   SMART; SM00317; SET; 1.
DR   PROSITE; PS50868; POST_SET; 1.
DR   PROSITE; PS50867; PRE_SET; 1.
DR   PROSITE; PS50280; SET; 1.
PE   4: Predicted;
KW   Chromosome {ECO:0000256|SAAS:SAAS00508265};
KW   Complete proteome {ECO:0000313|Proteomes:UP000008984};
KW   Methyltransferase {ECO:0000256|SAAS:SAAS00590675,
KW   ECO:0000313|EMBL:EGR45341.1};
KW   Nucleus {ECO:0000256|SAAS:SAAS00574642};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008984};
KW   S-adenosyl-L-methionine {ECO:0000256|SAAS:SAAS00591079};
KW   Transferase {ECO:0000256|SAAS:SAAS00591533,
KW   ECO:0000313|EMBL:EGR45341.1}.
FT   DOMAIN       63    129       Pre-SET. {ECO:0000259|PROSITE:PS50867}.
FT   DOMAIN      132    267       SET. {ECO:0000259|PROSITE:PS50280}.
FT   DOMAIN      286    302       Post-SET. {ECO:0000259|PROSITE:PS50868}.
SQ   SEQUENCE   302 AA;  34066 MW;  124113FE5BDACD76 CRC64;
     MEAVTRQHFF FHDQPLRAFP AHKTIPVTIV NEVDQAVIPP NFRFVDRMVL RRGVEPAEDS
     FRSGCSCESD DACQYTGCLT KRKAYAYHSH GAKAGLLRSK MLNSKEPLYE CHAGCSCSMS
     CPNRVVERGR TVPLQIFRTP DRGWGVHAQA AIKKGQFVDR YYGEIITSAE ADRRRTAAAF
     SQRKDVYLFA LDKFTDPDSL DARLRGPPLE VDGEFQSGPT RFINHSCEPN LRIFARVGDH
     ADKHIHDLAL FAIRDIPRGE ELTFDYVDGV MTGDLAGMEE QEAHGEMAKC LCGSRKCRGY
     LW
//
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