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Database: UniProt/TrEMBL
Entry: G2PCR8_STRVO
LinkDB: G2PCR8_STRVO
Original site: G2PCR8_STRVO 
ID   G2PCR8_STRVO            Unreviewed;       699 AA.
AC   G2PCR8;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   28-MAR-2018, entry version 43.
DE   RecName: Full=Catalase {ECO:0000256|PIRNR:PIRNR038927, ECO:0000256|RuleBase:RU000498};
DE            EC=1.11.1.6 {ECO:0000256|PIRNR:PIRNR038927, ECO:0000256|RuleBase:RU000498};
GN   ORFNames=Strvi_2526 {ECO:0000313|EMBL:AEM82246.1};
OS   Streptomyces violaceusniger Tu 4113.
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces.
OX   NCBI_TaxID=653045 {ECO:0000313|EMBL:AEM82246.1, ECO:0000313|Proteomes:UP000008703};
RN   [1] {ECO:0000313|EMBL:AEM82246.1, ECO:0000313|Proteomes:UP000008703}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tu 4133 {ECO:0000313|Proteomes:UP000008703};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA   Peters L., Ivanova N., Daligault H., Detter J.C., Han C., Tapia R.,
RA   Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Hagen A.,
RA   Katz L., Fiedler H.-P., Keasling J., Fortman J., Woyke T.;
RT   "Complete sequence of chromosome of Streptomyces violaceusniger Tu
RT   4113.";
RL   Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Serves to protect cells from the toxic effects of
CC       hydrogen peroxide. {ECO:0000256|PIRNR:PIRNR038927}.
CC   -!- CATALYTIC ACTIVITY: 2 H(2)O(2) = O(2) + 2 H(2)O.
CC       {ECO:0000256|PIRNR:PIRNR038927, ECO:0000256|RuleBase:RU000498}.
CC   -!- COFACTOR:
CC       Name=heme; Xref=ChEBI:CHEBI:30413;
CC         Evidence={ECO:0000256|PIRNR:PIRNR038927,
CC         ECO:0000256|PIRSR:PIRSR038927-2};
CC   -!- SIMILARITY: Belongs to the catalase family.
CC       {ECO:0000256|PIRNR:PIRNR038927, ECO:0000256|RuleBase:RU000498}.
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DR   EMBL; CP002994; AEM82246.1; -; Genomic_DNA.
DR   RefSeq; WP_014055751.1; NC_015957.1.
DR   ProteinModelPortal; G2PCR8; -.
DR   STRING; 653045.Strvi_2526; -.
DR   EnsemblBacteria; AEM82246; AEM82246; Strvi_2526.
DR   GeneID; 32483705; -.
DR   KEGG; svl:Strvi_2526; -.
DR   eggNOG; ENOG4105CH6; Bacteria.
DR   eggNOG; COG0753; LUCA.
DR   KO; K03781; -.
DR   OrthoDB; POG091H0424; -.
DR   BioCyc; SVIO653045:GHK6-2245-MONOMER; -.
DR   Proteomes; UP000008703; Chromosome.
DR   GO; GO:0004096; F:catalase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0020037; F:heme binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0042744; P:hydrogen peroxide catabolic process; IEA:UniProtKB-UniRule.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:InterPro.
DR   Gene3D; 2.40.180.10; -; 1.
DR   Gene3D; 3.40.50.880; -; 1.
DR   InterPro; IPR018028; Catalase.
DR   InterPro; IPR024708; Catalase_AS.
DR   InterPro; IPR024712; Catalase_clade2.
DR   InterPro; IPR011614; Catalase_core.
DR   InterPro; IPR037060; Catalase_core_sf.
DR   InterPro; IPR002226; Catalase_haem_BS.
DR   InterPro; IPR010582; Catalase_immune_responsive.
DR   InterPro; IPR020835; Catalase_sf.
DR   InterPro; IPR029062; Class_I_gatase-like.
DR   InterPro; IPR002818; DJ-1/PfpI.
DR   PANTHER; PTHR42821; PTHR42821; 1.
DR   Pfam; PF00199; Catalase; 1.
DR   Pfam; PF06628; Catalase-rel; 1.
DR   Pfam; PF01965; DJ-1_PfpI; 1.
DR   PIRSF; PIRSF038927; Catalase_clade2; 1.
DR   PRINTS; PR00067; CATALASE.
DR   SMART; SM01060; Catalase; 1.
DR   SUPFAM; SSF52317; SSF52317; 1.
DR   SUPFAM; SSF56634; SSF56634; 1.
DR   PROSITE; PS00437; CATALASE_1; 1.
DR   PROSITE; PS00438; CATALASE_2; 1.
DR   PROSITE; PS51402; CATALASE_3; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000008703};
KW   Heme {ECO:0000256|PIRNR:PIRNR038927, ECO:0000256|RuleBase:RU000498};
KW   Hydrogen peroxide {ECO:0000256|PIRNR:PIRNR038927,
KW   ECO:0000256|RuleBase:RU000498};
KW   Iron {ECO:0000256|PIRNR:PIRNR038927, ECO:0000256|PIRSR:PIRSR038927-2,
KW   ECO:0000256|RuleBase:RU000498};
KW   Metal-binding {ECO:0000256|PIRNR:PIRNR038927,
KW   ECO:0000256|PIRSR:PIRSR038927-2, ECO:0000256|RuleBase:RU000498};
KW   Oxidoreductase {ECO:0000256|PIRNR:PIRNR038927,
KW   ECO:0000256|RuleBase:RU000498};
KW   Peroxidase {ECO:0000256|PIRNR:PIRNR038927,
KW   ECO:0000256|RuleBase:RU000498};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008703}.
FT   DOMAIN       24    411       Catalase. {ECO:0000259|SMART:SM01060}.
FT   ACT_SITE     71     71       {ECO:0000256|PIRSR:PIRSR038927-1}.
FT   ACT_SITE    144    144       {ECO:0000256|PIRSR:PIRSR038927-1}.
FT   METAL       358    358       Iron (heme axial ligand).
FT                                {ECO:0000256|PIRSR:PIRSR038927-2}.
SQ   SEQUENCE   699 AA;  77420 MW;  36AF56FFDB3A8DE4 CRC64;
     MTEDRKERQR DQYRAPDPAE GPLTTDQGVA VDHTDDSLTV GERGPTLMED FHFREKITHF
     DHERIPERVV HARGAGAYGY FEPYESCAEF TRAAFLQDPS VRTPVFVRFS TVQGPRGSAD
     TVRDVRGFAT KFYTSEGNYD LVGNNMPVFF IQDGIKFPDF VHALKPEPHN DIPTGASAHD
     TLWDFVSLQP ETMHMMMWLM SDRAIPRSFR MMQGFGVHTF RFVDAQGRGT FVKFHWKPKL
     GVHSLVWDEA QEAAGRDPDF NRRDLWQAIE AGQYPEYELG VQLIPEEDEF NFDFDLLDAT
     KIIPEEQVPV RPIGHMVLNR NPDNFFAETE QVAFHTANVV PGIDFTNDPL LQARNFSYLD
     TQLIRLGGPN FSQLPVNQPV TPARTNHRDG YHQTMIHKGT NYSPNSLGGG CPALAGADGY
     AFSHYAERVE GHKIRKRSES FKDFYSQAAL FWNSMSDWEK RHIVDAFRFE LGKVEAVHVR
     ERTVEQLARV DYGLASQVAQ GIGVAMPEPG ANTHKPQASP ALSLENLQGD GSIRTRQIAV
     LVTDGVDTAQ LTQAQEALTA QGAVVEALAP HDGKVVGADG NGYAVDRALP TVASVLYDAV
     LLPGGPPGTP DLASDSAAMR FVRDAYRHGK PIGALGSGVG ILSSLDPEGL HIASGHGHVC
     ADRGVVTDTT TGTASEEFTR AFTEAIAAHR HWDRPRVRC
//
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