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Database: UniProt/TrEMBL
Entry: G2SGR3_RHOMR
LinkDB: G2SGR3_RHOMR
Original site: G2SGR3_RHOMR 
ID   G2SGR3_RHOMR            Unreviewed;       319 AA.
AC   G2SGR3;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   19-FEB-2014, entry version 15.
DE   RecName: Full=Aspartate carbamoyltransferase;
DE            EC=2.1.3.2;
DE   AltName: Full=Aspartate transcarbamylase;
GN   Name=pyrB; ORFNames=Rhom172_2159;
OS   Rhodothermus marinus SG0.5JP17-172.
OC   Bacteria; Bacteroidetes; Bacteroidetes Order II. Incertae sedis;
OC   Rhodothermaceae; Rhodothermus.
OX   NCBI_TaxID=762570;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=SG0.5JP17-172;
RG   US DOE Joint Genome Institute;
RA   Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA   Peters L., Ovchinnikova G., Chertkov O., Detter J.C., Han C.,
RA   Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I.,
RA   Gladden J., Woyke T.;
RT   "Complete sequence of chromosome of Rhodothermus marinus SG0.5JP17-
RT   172.";
RL   Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: Carbamoyl phosphate + L-aspartate = phosphate
CC       + N-carbamoyl-L-aspartate.
CC   -!- PATHWAY: Pyrimidine metabolism; UMP biosynthesis via de novo
CC       pathway; (S)-dihydroorotate from bicarbonate: step 2/3.
CC   -!- SIMILARITY: Belongs to the ATCase/OTCase family.
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DR   EMBL; CP003029; AEN74060.1; -; Genomic_DNA.
DR   RefSeq; YP_004825897.1; NC_015966.1.
DR   EnsemblBacteria; AEN74060; AEN74060; Rhom172_2159.
DR   GeneID; 11114053; -.
DR   KEGG; rmg:Rhom172_2159; -.
DR   KO; K00609; -.
DR   BioCyc; RMAR762570:GJAN-2201-MONOMER; -.
DR   UniPathway; UPA00070; UER00116.
DR   GO; GO:0016597; F:amino acid binding; IEA:InterPro.
DR   GO; GO:0004070; F:aspartate carbamoyltransferase activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006207; P:'de novo' pyrimidine nucleobase biosynthetic process; IEA:InterPro.
DR   GO; GO:0044205; P:'de novo' UMP biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.
DR   Gene3D; 3.40.50.1370; -; 2.
DR   HAMAP; MF_00001; Asp_carb_tr; 1.
DR   InterPro; IPR006132; Asp/Orn_carbamoyltranf_P-bd.
DR   InterPro; IPR006130; Asp/Orn_carbamoylTrfase.
DR   InterPro; IPR002082; Asp_carbamoyltransf.
DR   InterPro; IPR006131; Asp_carbamoyltransf_Asp/Orn-bd.
DR   Pfam; PF00185; OTCace; 1.
DR   Pfam; PF02729; OTCace_N; 1.
DR   PRINTS; PR00100; AOTCASE.
DR   PRINTS; PR00101; ATCASE.
DR   SUPFAM; SSF53671; SSF53671; 1.
DR   TIGRFAMs; TIGR00670; asp_carb_tr; 1.
DR   PROSITE; PS00097; CARBAMOYLTRANSFERASE; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Pyrimidine biosynthesis; Transferase.
SQ   SEQUENCE   319 AA;  35335 MW;  F7355E3A1A39ADA0 CRC64;
     MSTSTETPLQ GRLRHRHLLG LATYSAEEIQ LILQTARQFR EVLERPIRRV PTLRGVTVVN
     LFFEPSTRTR ISFELAEKRL SADVVNFSAA GSSVVKGETL KDTARNLEAM KIDMVVIRHR
     SPGAAHFLTR CIDAVVINAG DGAHEHPTQA LLDLLTISDY FPSFEGLNVS IIGDITHSRV
     ARSNIYGLKA LGANVTLCGP RTLMPVGIEE LGVRVTYRLE EALEGCDVAM ALRLQLERQT
     AGLFPSLREY HERYGIKLEH LERYPDLLVM HPGPVNRGVE LASEVVDHER AIILNQVTNG
     VAVRMAVLYL LAGMPEAAD
//
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