ID G2SGR3_RHOMR Unreviewed; 319 AA.
AC G2SGR3;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 03-APR-2013, entry version 11.
DE RecName: Full=Aspartate carbamoyltransferase;
DE EC=2.1.3.2;
DE AltName: Full=Aspartate transcarbamylase;
GN Name=pyrB; ORFNames=Rhom172_2159;
OS Rhodothermus marinus SG0.5JP17-172.
OC Bacteria; Bacteroidetes; Bacteroidetes Order II. Incertae sedis;
OC Rhodothermaceae; Rhodothermus.
OX NCBI_TaxID=762570;
RN [1]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=SG0.5JP17-172;
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Ovchinnikova G., Chertkov O., Detter J.C., Han C.,
RA Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I.,
RA Gladden J., Woyke T.;
RT "Complete sequence of chromosome of Rhodothermus marinus SG0.5JP17-
RT 172.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY: Carbamoyl phosphate + L-aspartate = phosphate
CC + N-carbamoyl-L-aspartate.
CC -!- PATHWAY: Pyrimidine metabolism; UMP biosynthesis via de novo
CC pathway; (S)-dihydroorotate from bicarbonate: step 2/3.
CC -!- SIMILARITY: Belongs to the ATCase/OTCase family.
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DR EMBL; CP003029; AEN74060.1; -; Genomic_DNA.
DR RefSeq; YP_004825897.1; NC_015966.1.
DR EnsemblBacteria; AEN74060; AEN74060; Rhom172_2159.
DR GeneID; 11114053; -.
DR KEGG; rmg:Rhom172_2159; -.
DR KO; K00609; -.
DR BioCyc; RMAR762570:GJAN-2201-MONOMER; -.
DR UniPathway; UPA00070; UER00116.
DR GO; GO:0016597; F:amino acid binding; IEA:InterPro.
DR GO; GO:0004070; F:aspartate carbamoyltransferase activity; IEA:HAMAP.
DR GO; GO:0006207; P:'de novo' pyrimidine nucleobase biosynthetic process; IEA:InterPro.
DR GO; GO:0044205; P:'de novo' UMP biosynthetic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.
DR HAMAP; MF_00001; Asp_carb_tr; 1; -.
DR InterPro; IPR006132; Asp/Orn_carbamoyltranf_P-bd.
DR InterPro; IPR006130; Asp/Orn_carbamoylTrfase.
DR InterPro; IPR002082; Asp_carbamoyltransf.
DR InterPro; IPR006131; Asp_carbamoyltransf_Asp/Orn-bd.
DR Pfam; PF00185; OTCace; 1.
DR Pfam; PF02729; OTCace_N; 1.
DR PRINTS; PR00100; AOTCASE.
DR PRINTS; PR00101; ATCASE.
DR SUPFAM; SSF53671; Asp/Orn_carbamoyltranf; 1.
DR TIGRFAMs; TIGR00670; asp_carb_tr; 1.
DR PROSITE; PS00097; CARBAMOYLTRANSFERASE; 1.
PE 3: Inferred from homology;
KW Pyrimidine biosynthesis; Transferase.
SQ SEQUENCE 319 AA; 35335 MW; F7355E3A1A39ADA0 CRC64;
MSTSTETPLQ GRLRHRHLLG LATYSAEEIQ LILQTARQFR EVLERPIRRV PTLRGVTVVN
LFFEPSTRTR ISFELAEKRL SADVVNFSAA GSSVVKGETL KDTARNLEAM KIDMVVIRHR
SPGAAHFLTR CIDAVVINAG DGAHEHPTQA LLDLLTISDY FPSFEGLNVS IIGDITHSRV
ARSNIYGLKA LGANVTLCGP RTLMPVGIEE LGVRVTYRLE EALEGCDVAM ALRLQLERQT
AGLFPSLREY HERYGIKLEH LERYPDLLVM HPGPVNRGVE LASEVVDHER AIILNQVTNG
VAVRMAVLYL LAGMPEAAD
//
