GenomeNet

Database: UniProt/TrEMBL
Entry: G2TNM4_BACCO
LinkDB: G2TNM4_BACCO
Original site: G2TNM4_BACCO 
ID   G2TNM4_BACCO            Unreviewed;       668 AA.
AC   G2TNM4;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   11-JUN-2014, entry version 18.
DE   RecName: Full=Transketolase;
DE            EC=2.2.1.1;
GN   ORFNames=Bcoa_3020;
OS   Bacillus coagulans 36D1.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=345219;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=36D1;
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T.,
RA   Dalin E., Tice H., Bruce D., Goodwin L., Chertkov O., Brettin T.,
RA   Han C., Detter C., Pitluck S., Shanmugam K.T.;
RL   Submitted (APR-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=36D1;
RX   PubMed=22675583; DOI=10.4056/sigs.2365342;
RA   Rhee M.S., Moritz B.E., Xie G., Glavina Del Rio T., Dalin E., Tice H.,
RA   Bruce D., Goodwin L., Chertkov O., Brettin T., Han C., Detter C.,
RA   Pitluck S., Land M.L., Patel M., Ou M., Harbrucker R., Ingram L.O.,
RA   Shanmugam K.T.;
RT   "Complete Genome Sequence of a thermotolerant sporogenic lactic acid
RT   bacterium, Bacillus coagulans strain 36D1.";
RL   Stand. Genomic Sci. 5:331-340(2011).
RN   [3]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=36D1;
RA   Shanmugan K.T.;
RL   Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Catalyzes the transfer of a two-carbon ketol group from
CC       a ketose donor to an aldose acceptor, via a covalent intermediate
CC       with the cofactor thiamine pyrophosphate (By similarity).
CC   -!- CATALYTIC ACTIVITY: Sedoheptulose 7-phosphate + D-glyceraldehyde
CC       3-phosphate = D-ribose 5-phosphate + D-xylulose 5-phosphate.
CC   -!- COFACTOR: Binds 1 magnesium ion per subunit. Can also utilize
CC       other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+)
CC       (By similarity).
CC   -!- COFACTOR: Binds 1 thiamine pyrophosphate per subunit (By
CC       similarity).
CC   -!- SUBUNIT: Homodimer (By similarity).
CC   -!- SIMILARITY: Belongs to the transketolase family.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; CP003056; AEP02196.1; -; Genomic_DNA.
DR   RefSeq; YP_004860976.1; NC_016023.1.
DR   ProteinModelPortal; G2TNM4; -.
DR   EnsemblBacteria; AEP02196; AEP02196; Bcoa_3020.
DR   GeneID; 11173949; -.
DR   KEGG; bag:Bcoa_3020; -.
DR   KO; K00615; -.
DR   BioCyc; BCOA345219:GH5A-2985-MONOMER; -.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004802; F:transketolase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.40.50.920; -; 1.
DR   Gene3D; 3.40.50.970; -; 2.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR009014; Transketo_C/Pyr-ferredox_oxred.
DR   InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR   InterPro; IPR005478; Transketolase_bac-like.
DR   InterPro; IPR020826; Transketolase_BS.
DR   InterPro; IPR005476; Transketolase_C.
DR   InterPro; IPR005474; Transketolase_N.
DR   Pfam; PF02779; Transket_pyr; 1.
DR   Pfam; PF02780; Transketolase_C; 1.
DR   Pfam; PF00456; Transketolase_N; 1.
DR   SMART; SM00861; Transket_pyr; 1.
DR   SUPFAM; SSF52518; SSF52518; 2.
DR   SUPFAM; SSF52922; SSF52922; 1.
DR   TIGRFAMs; TIGR00232; tktlase_bact; 1.
DR   PROSITE; PS00801; TRANSKETOLASE_1; 1.
DR   PROSITE; PS00802; TRANSKETOLASE_2; 1.
PE   3: Inferred from homology;
KW   Calcium; Complete proteome; Magnesium; Metal-binding;
KW   Thiamine pyrophosphate; Transferase.
SQ   SEQUENCE   668 AA;  72852 MW;  A4BF4AFD09A6424C CRC64;
     MFDKTDELAV TTIRTLSIDA IEKAKSGHPG LPMGAAPMAY TLWTRYLNHN PENPHWFNRD
     RFVLSAGHGS MLLYSLLHLS GYALSMDDIK NFRQYGSKTP GHPEYGHTEG VEATTGPLGQ
     GIAMSVGMAM AERHLAAVYN KENFPVIDHY TYALCGDGDL MEGVSAEAAS LAGHLKLGRL
     IVLYDSNDIS LDGDLNKAFS ESVADRFKAY GWQYLRVEDG NDMAQVAKAI EEAKADTSRP
     TLIEVKTIIG YGSPNKSGKS AAHGAPLGED ELKLTKEAYK WTFEEDFYVP DEVYARFREL
     VVENGVKKEQ EWASLFEAYE KQYPQLAAEL KQAIKGGLPD GWDKDIPVYE EGKTLASRAA
     SGEVLNAVSK HLPSLFGGSA DLAGSNNTRL KEDKDYMPDA YEGRNIWFGV REFAMGAAMN
     GMALHGGVHV YGGTFFVFSD YLRPAIRLAA LMGLPVTYVF THDSIAVGED GPTHEPVEQL
     PSLRAMPGLS VIRPADGNET AAAWRLALSS ENHPTALVLT RQGLPTLKGT SEKALEGVSK
     GAYVVSPAQK ETADVLLLAS GSEVHLAVLA QQQLAEQKID AAVVSMPSWD RFEQQSKAYK
     ESVLPAQVKK RLAIEMASPF GWERYTGDEG DILSVNTFGA SGNGKTVMEK YGFTVENVVA
     RVKKLLGM
//
DBGET integrated database retrieval system