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Database: UniProt/TrEMBL
Entry: G2WW33_VERDV
LinkDB: G2WW33_VERDV
Original site: G2WW33_VERDV 
ID   G2WW33_VERDV            Unreviewed;       559 AA.
AC   G2WW33;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   25-OCT-2017, entry version 30.
DE   RecName: Full=Glutamate decarboxylase {ECO:0000256|RuleBase:RU361171};
DE            EC=4.1.1.15 {ECO:0000256|RuleBase:RU361171};
GN   ORFNames=VDAG_01819 {ECO:0000313|EMBL:EGY19803.1};
OS   Verticillium dahliae (strain VdLs.17 / ATCC MYA-4575 / FGSC 10137)
OS   (Verticillium wilt).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
OC   Sordariomycetes; Hypocreomycetidae; Glomerellales;
OC   Plectosphaerellaceae; Verticillium.
OX   NCBI_TaxID=498257 {ECO:0000313|Proteomes:UP000001611};
RN   [1] {ECO:0000313|Proteomes:UP000001611}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VdLs.17 / ATCC MYA-4575 / FGSC 10137
RC   {ECO:0000313|Proteomes:UP000001611};
RX   PubMed=21829347; DOI=10.1371/journal.ppat.1002137;
RA   Klosterman S.J., Subbarao K.V., Kang S., Veronese P., Gold S.E.,
RA   Thomma B.P.H.J., Chen Z., Henrissat B., Lee Y.-H., Park J.,
RA   Garcia-Pedrajas M.D., Barbara D.J., Anchieta A., de Jonge R.,
RA   Santhanam P., Maruthachalam K., Atallah Z., Amyotte S.G., Paz Z.,
RA   Inderbitzin P., Hayes R.J., Heiman D.I., Young S., Zeng Q., Engels R.,
RA   Galagan J., Cuomo C.A., Dobinson K.F., Ma L.-J.;
RT   "Comparative genomics yields insights into niche adaptation of plant
RT   vascular wilt pathogens.";
RL   PLoS Pathog. 7:E1002137-E1002137(2011).
CC   -!- CATALYTIC ACTIVITY: L-glutamate = 4-aminobutanoate + CO(2).
CC       {ECO:0000256|RuleBase:RU361171}.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|PIRSR:PIRSR602129-50,
CC         ECO:0000256|RuleBase:RU361171};
CC   -!- SIMILARITY: Belongs to the group II decarboxylase family.
CC       {ECO:0000256|RuleBase:RU361171}.
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DR   EMBL; DS572697; EGY19803.1; -; Genomic_DNA.
DR   RefSeq; XP_009656143.1; XM_009657848.1.
DR   EnsemblFungi; EGY19803; EGY19803; VDAG_01819.
DR   GeneID; 20703282; -.
DR   KEGG; vda:VDAG_01819; -.
DR   InParanoid; G2WW33; -.
DR   KO; K01580; -.
DR   OrthoDB; EOG092C1P0W; -.
DR   Proteomes; UP000001611; Unassembled WGS sequence.
DR   GO; GO:0004351; F:glutamate decarboxylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0034599; P:cellular response to oxidative stress; IEA:EnsemblFungi.
DR   GO; GO:0006538; P:glutamate catabolic process; IEA:EnsemblFungi.
DR   Gene3D; 3.40.640.10; -; 1.
DR   Gene3D; 3.90.1150.10; -; 1.
DR   InterPro; IPR010107; Glutamate_decarboxylase.
DR   InterPro; IPR002129; PyrdxlP-dep_de-COase.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major_sub1.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_sub2.
DR   PANTHER; PTHR43321; PTHR43321; 1.
DR   Pfam; PF00282; Pyridoxal_deC; 1.
DR   SUPFAM; SSF53383; SSF53383; 2.
DR   TIGRFAMs; TIGR01788; Glu-decarb-GAD; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000001611};
KW   Decarboxylase {ECO:0000256|RuleBase:RU361171};
KW   Lyase {ECO:0000256|RuleBase:RU361171};
KW   Pyridoxal phosphate {ECO:0000256|PIRSR:PIRSR602129-50,
KW   ECO:0000256|RuleBase:RU361171};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001611}.
FT   MOD_RES     303    303       N6-(pyridoxal phosphate)lysine.
FT                                {ECO:0000256|PIRSR:PIRSR602129-50}.
SQ   SEQUENCE   559 AA;  62551 MW;  EBE086A50EFE2F61 CRC64;
     MSLATHVDPD EIIQRLQASH ITAPGHTNLN SQGRAAHIHP FDTQYSSQEN IPKFKIPQDG
     APADTVYHMV RNQLDLDGKP NLNLASFVST FLEPNAQQLM EENLTKNLAD SDEYPAMMEI
     HQRCISIIAH LWGVQPGERA IGSACTGSSE AIHLGGLAMK RRWQEKRKAE GKDTSKPNII
     MGANAQVALE KFARYFEVEA RILPVSAESR FRLDPELVKE NIDENTIGVF VILGSTYTGH
     YEPVEEISKI LDDYEAKTGV DIPIHVDAAS GGFIAPFTDA GAGGAKWNFE LPRVKSINTS
     GHKFGLVSAG LGWIIWRDEA YLPEFLVFEL HYLGGTEKSY TLNFSRPGAQ VVVQYYNLVH
     LGFSGYRGIM ENCLTNARLL ANSLEETGWY TVVSDIHRRV DGGSDRAPKS GTEGAEQEPP
     RETSADYVAG LPVVSFRLTD EFQKQYSHIK QETVSLFLRA KGWIIPNYAL PPSEEKTEIL
     RVVVRENMTF DLLELLLTDI VTVTETLIED DKVDLSSLKR HHIGHGRRPV TKQDHERHKR
     RLEGHGKKRP QDGIHRTVC
//
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