GenomeNet

Database: UniProt/TrEMBL
Entry: G3WM90_SARHA
LinkDB: G3WM90_SARHA
Original site: G3WM90_SARHA 
ID   G3WM90_SARHA            Unreviewed;       727 AA.
AC   G3WM90;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   25-OCT-2017, entry version 43.
DE   SubName: Full=Coagulation factor XIII A chain {ECO:0000313|Ensembl:ENSSHAP00000016545};
GN   Name=F13A1 {ECO:0000313|Ensembl:ENSSHAP00000016545};
OS   Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Metatheria; Dasyuromorphia; Dasyuridae; Sarcophilus.
OX   NCBI_TaxID=9305 {ECO:0000313|Ensembl:ENSSHAP00000016545, ECO:0000313|Proteomes:UP000007648};
RN   [1] {ECO:0000313|Ensembl:ENSSHAP00000016545}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=21709235; DOI=10.1073/pnas.1102838108;
RA   Miller W., Hayes V.M., Ratan A., Petersen D.C., Wittekindt N.E.,
RA   Miller J., Walenz B., Knight J., Qi J., Zhao F., Wang Q.,
RA   Bedoya-Reina O.C., Katiyar N., Tomsho L.P., Kasson L.M., Hardie R.A.,
RA   Woodbridge P., Tindall E.A., Bertelsen M.F., Dixon D., Pyecroft S.,
RA   Helgen K.M., Lesk A.M., Pringle T.H., Patterson N., Zhang Y.,
RA   Kreiss A., Woods G.M., Jones M.E., Schuster S.C.;
RT   "Genetic diversity and population structure of the endangered
RT   marsupial Sarcophilus harrisii (Tasmanian devil).";
RL   Proc. Natl. Acad. Sci. U.S.A. 108:12348-12353(2011).
RN   [2] {ECO:0000313|Ensembl:ENSSHAP00000016545}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2011) to UniProtKB.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSSHAP00000016545}.
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DR   EMBL; AEFK01064123; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AEFK01064124; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AEFK01064125; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AEFK01064126; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AEFK01064127; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AEFK01064128; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AEFK01064129; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AEFK01064130; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AEFK01064131; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AEFK01064132; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_003760255.1; XM_003760207.2.
DR   STRING; 9305.ENSSHAP00000016545; -.
DR   Ensembl; ENSSHAT00000016683; ENSSHAP00000016545; ENSSHAG00000014073.
DR   GeneID; 100931287; -.
DR   KEGG; shr:100931287; -.
DR   CTD; 2162; -.
DR   eggNOG; ENOG410IFMV; Eukaryota.
DR   eggNOG; ENOG410XQEZ; LUCA.
DR   GeneTree; ENSGT00760000119108; -.
DR   InParanoid; G3WM90; -.
DR   KO; K03917; -.
DR   OMA; CEEDAVY; -.
DR   OrthoDB; EOG091G030K; -.
DR   TreeFam; TF324278; -.
DR   Proteomes; UP000007648; Unassembled WGS sequence.
DR   GO; GO:0072562; C:blood microparticle; IEA:Ensembl.
DR   GO; GO:0003810; F:protein-glutamine gamma-glutamyltransferase activity; IEA:Ensembl.
DR   GO; GO:0072378; P:blood coagulation, fibrin clot formation; IEA:Ensembl.
DR   GO; GO:0018149; P:peptide cross-linking; IEA:Ensembl.
DR   Gene3D; 2.60.40.10; -; 3.
DR   Gene3D; 3.90.260.10; -; 1.
DR   InterPro; IPR034810; Factor_XIII_A.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR002931; Transglutaminase-like.
DR   InterPro; IPR036985; Transglutaminase-like_sf.
DR   InterPro; IPR023608; Transglutaminase_animal.
DR   InterPro; IPR008958; Transglutaminase_C.
DR   InterPro; IPR036238; Transglutaminase_C_sf.
DR   InterPro; IPR001102; Transglutaminase_N.
DR   PANTHER; PTHR11590:SF42; PTHR11590:SF42; 1.
DR   Pfam; PF00927; Transglut_C; 2.
DR   Pfam; PF01841; Transglut_core; 1.
DR   Pfam; PF00868; Transglut_N; 1.
DR   PIRSF; PIRSF000459; TGM_EBP42; 1.
DR   SMART; SM00460; TGc; 1.
DR   SUPFAM; SSF49309; SSF49309; 2.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000007648};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007648}.
FT   DOMAIN      304    397       TGc. {ECO:0000259|SMART:SM00460}.
FT   ACT_SITE    312    312       {ECO:0000256|PIRSR:PIRSR000459-1}.
FT   ACT_SITE    371    371       {ECO:0000256|PIRSR:PIRSR000459-1}.
FT   ACT_SITE    394    394       {ECO:0000256|PIRSR:PIRSR000459-1}.
SQ   SEQUENCE   727 AA;  83132 MW;  ACE94EB1DB6DA1A2 CRC64;
     MSQGTFSGRR ALPPNNSNGE ENELPTEEIS GLLPRGVQLQ EFLNVTDVHL FKDSWDTNKV
     EHHTDRYYNE KLIVRRGQSF YIQIDFNRPY DPQRDIFRLE YVIGRYPQET KGTFIPVPIV
     SEFQSGKWGA KIILKENRSV RLSVQSSPEC IVGKFRMYIA VWTPYGIFRT KRNPETDTYI
     LFNPWCEEDA VYLDNEKERE EYVLNDLGVI FHGNFDDVKT RSWNYGQFED GILDACLYIM
     DKAQMDLSGR KNPVKVSRVA SAMINAKDDQ GVIVGSWDNI YAYGVAPSAW TGSVDILLEY
     QSSGNPVQYG QCWVFAGVLN TFFRCLGIPA RIVTNFFSAH DNNANLQMDI FLDEDGKINP
     KLTKDSVWNY HCWNEAWMTR PDLPVGFGGW QVVDSTPQEN SDGMYRCGPA SVQAIKHGHV
     CFQFDTPFVF AEVNSDLIYI TVKKDTTHMV EAVDKTHIGK LVITKEIGGD GKQDITENYK
     FPEGKEEERL ALETALMYGA KKPLDTEGIH QFRADIDMDF EVEKAVLGKD FKVTITFRNS
     TNRRYTATAY LSGNIVFYTG VAKSEFKNQT FDVKVEPYSF TNEEVQIKAG EYMGQLLEQA
     SLHFFVSARI NETSKVLAMQ KSTVLHIPTV NLKVRGQKVV GSDMVVTVEF TNPLNETLYN
     IWIHLDGPGV MKPTRKMFRE LPPNSTLTWE EVCRPWVPGS RKLMATLNCD ALRHVYGELD
     LEIQRRR
//
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