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Database: UniProt/TrEMBL
Entry: G4FFN9_THEMA
LinkDB: G4FFN9_THEMA
Original site: G4FFN9_THEMA 
ID   G4FFN9_THEMA            Unreviewed;       400 AA.
AC   G4FFN9;
DT   14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT   14-DEC-2011, sequence version 1.
DT   28-MAR-2018, entry version 59.
DE   RecName: Full=Elongation factor Tu {ECO:0000256|HAMAP-Rule:MF_00118, ECO:0000256|RuleBase:RU004061};
DE            Short=EF-Tu {ECO:0000256|HAMAP-Rule:MF_00118};
GN   Name=tuf {ECO:0000256|HAMAP-Rule:MF_00118};
GN   ORFNames=Tmari_1510 {ECO:0000313|EMBL:AGL50434.1};
OS   Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099).
OC   Bacteria; Thermotogae; Thermotogales; Thermotogaceae; Thermotoga.
OX   NCBI_TaxID=243274 {ECO:0000313|EMBL:AGL50434.1, ECO:0000313|Proteomes:UP000013901};
RN   [1] {ECO:0000313|EMBL:AGL50434.1, ECO:0000313|Proteomes:UP000013901}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43589 / MSB8 / DSM 3109 / JCM 10099
RC   {ECO:0000313|Proteomes:UP000013901};
RX   PubMed=23637642;
RA   Latif H., Lerman J.A., Portnoy V.A., Tarasova Y., Nagarajan H.,
RA   Schrimpe-Rutledge A.C., Smith R.D., Adkins J.N., Lee D.H., Qiu Y.,
RA   Zengler K.;
RT   "The genome organization of Thermotoga maritima reflects its
RT   lifestyle.";
RL   PLoS Genet. 9:E1003485-E1003485(2013).
CC   -!- FUNCTION: This protein promotes the GTP-dependent binding of
CC       aminoacyl-tRNA to the A-site of ribosomes during protein
CC       biosynthesis. {ECO:0000256|HAMAP-Rule:MF_00118}.
CC   -!- SUBUNIT: Monomer. {ECO:0000256|HAMAP-Rule:MF_00118}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00118}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class translation factor GTPase
CC       superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A
CC       subfamily. {ECO:0000256|HAMAP-Rule:MF_00118}.
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DR   EMBL; CP004077; AGL50434.1; -; Genomic_DNA.
DR   RefSeq; NP_229302.1; NC_000853.1.
DR   RefSeq; WP_004081839.1; NZ_CP011107.1.
DR   ProteinModelPortal; G4FFN9; -.
DR   SMR; G4FFN9; -.
DR   EnsemblBacteria; AGL50434; AGL50434; Tmari_1510.
DR   GeneID; 897995; -.
DR   KEGG; tma:TM1502; -.
DR   KEGG; tmi:THEMA_06790; -.
DR   KEGG; tmm:Tmari_1510; -.
DR   KEGG; tmw:THMA_1534; -.
DR   PATRIC; fig|243274.17.peg.1510; -.
DR   eggNOG; ENOG4105CGV; Bacteria.
DR   eggNOG; COG0050; LUCA.
DR   KO; K02358; -.
DR   OMA; YGHIDCP; -.
DR   Proteomes; UP000013901; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-UniRule.
DR   CDD; cd03697; EFTU_II; 1.
DR   HAMAP; MF_00118_B; EF_Tu_B; 1.
DR   InterPro; IPR004161; EFTu-like_2.
DR   InterPro; IPR033720; EFTU_2.
DR   InterPro; IPR031157; G_TR_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005225; Small_GTP-bd_dom.
DR   InterPro; IPR000795; TF_GTP-bd_dom.
DR   InterPro; IPR009000; Transl_B-barrel_sf.
DR   InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR   InterPro; IPR004541; Transl_elong_EFTu/EF1A_bac/org.
DR   InterPro; IPR004160; Transl_elong_EFTu/EF1A_C.
DR   Pfam; PF00009; GTP_EFTU; 1.
DR   Pfam; PF03144; GTP_EFTU_D2; 1.
DR   Pfam; PF03143; GTP_EFTU_D3; 1.
DR   PRINTS; PR00315; ELONGATNFCT.
DR   SUPFAM; SSF50447; SSF50447; 1.
DR   SUPFAM; SSF50465; SSF50465; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00485; EF-Tu; 1.
DR   TIGRFAMs; TIGR00231; small_GTP; 1.
DR   PROSITE; PS00301; G_TR_1; 1.
DR   PROSITE; PS51722; G_TR_2; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000013901};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00118};
KW   Elongation factor {ECO:0000256|HAMAP-Rule:MF_00118,
KW   ECO:0000313|EMBL:AGL50434.1};
KW   GTP-binding {ECO:0000256|HAMAP-Rule:MF_00118};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00118};
KW   Protein biosynthesis {ECO:0000256|HAMAP-Rule:MF_00118}.
FT   DOMAIN       10    208       Tr-type G. {ECO:0000259|PROSITE:PS51722}.
FT   NP_BIND      19     26       GTP. {ECO:0000256|HAMAP-Rule:MF_00118}.
FT   NP_BIND      81     85       GTP. {ECO:0000256|HAMAP-Rule:MF_00118}.
FT   NP_BIND     136    139       GTP. {ECO:0000256|HAMAP-Rule:MF_00118}.
SQ   SEQUENCE   400 AA;  44467 MW;  73F479FE4F69E9A5 CRC64;
     MAKEKFVRTK PHVNVGTIGH IDHGKSTLTA AITKYLSLKG LAQYIPYDQI DKAPEEKARG
     ITINITHVEY ETEKRHYAHI DCPGHADYIK NMITGAAQMD GAILVVAATD GPMPQTREHV
     LLARQVEVPY MIVFINKTDM VDDPELIDLV EMEVRDLLSQ YGYPGDEVPV IRGSALKAVE
     APNDPNHEAY KPIQELLDAM DNYIPDPQRD VDKPFLMPIE DVFSITGRGT VVTGRIERGR
     IRPGDEVEII GLSYEIKKTV VTSVEMFRKE LDEGIAGDNV GCLLRGIDKD EVERGQVLAA
     PGSIKPHKRF KAQIYVLKKE EGGRHTPFTK GYKPQFYIRT ADVTGEIVGL PEGVEMVMPG
     DHVEMEIELI YPVAIEKGQR FAVREGGRTV GAGVVTEVIE
//
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