ID   G4P064_BACPN            Unreviewed;       490 AA.
AC   G4P064;
DT   14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT   14-DEC-2011, sequence version 1.
DT   03-APR-2013, entry version 12.
DE   RecName: Full=Nicotinate phosphoribosyltransferase;
DE            EC=2.4.2.11;
GN   Name=pncB; ORFNames=GYO_3466;
OS   Bacillus subtilis subsp. spizizenii TU-B-10.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=1052585;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=TU-B-10;
RX   PubMed=22493193; DOI=10.1128/JB.05675-11;
RA   Earl A.M., Eppinger M., Fricke W.F., Rosovitz M.J., Rasko D.A.,
RA   Daugherty S., Losick R., Kolter R., Ravel J.;
RT   "Whole-Genome Sequences of Bacillus subtilis and Close Relatives.";
RL   J. Bacteriol. 194:2378-2379(2012).
CC   -!- CATALYTIC ACTIVITY: Beta-nicotinate D-ribonucleotide + diphosphate
CC       = nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate.
CC   -!- CATALYTIC ACTIVITY: Nicotinate D-ribonucleotide + diphosphate =
CC       nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate.
CC   -!- PATHWAY: Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-
CC       ribonucleotide from nicotinate: step 1/1.
CC   -!- SIMILARITY: Belongs to the NAPRTase family.
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DR   EMBL; CP002905; AEP88043.1; -; Genomic_DNA.
DR   RefSeq; YP_004878675.1; NC_016047.1.
DR   EnsemblBacteria; AEP88043; AEP88043; GYO_3466.
DR   GeneID; 11240779; -.
DR   KEGG; bst:GYO_3466; -.
DR   KO; K00763; -.
DR   BioCyc; BSUB1052585:GJWW-3433-MONOMER; -.
DR   UniPathway; UPA00253; UER00457.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0004516; F:nicotinate phosphoribosyltransferase activity; IEA:EC.
DR   GO; GO:0004514; F:nicotinate-nucleotide diphosphorylase (carboxylating) activity; IEA:InterPro.
DR   GO; GO:0009435; P:NAD biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0019358; P:nicotinate nucleotide salvage; IEA:InterPro.
DR   InterPro; IPR015977; Nic_PRibTrfase-like.
DR   InterPro; IPR007229; Nic_PRibTrfase-rel.
DR   InterPro; IPR006405; Nic_PRibTrfase_put.
DR   InterPro; IPR002638; Quinolinate_PRibosylTrfase_C.
DR   PANTHER; PTHR11098:SF1; PTHR11098:SF1; 1.
DR   Pfam; PF04095; NAPRTase; 1.
DR   PIRSF; PIRSF000484; NAPRT; 1.
DR   SUPFAM; SSF51690; Q_phspho_trans; 1.
DR   TIGRFAMs; TIGR01513; NAPRTase_put; 1.
PE   3: Inferred from homology;
KW   Glycosyltransferase; Pyridine nucleotide biosynthesis; Transferase.
SQ   SEQUENCE   490 AA;  56221 MW;  A1E0662CC560C560 CRC64;
     MLEYGFKDDS LSLHTDLYQI NMAETYWRDG IHEKKAIFEL FFRRLPFENG YAVFAGLEKA
     IEYLENFKFT DSDLNYLQEE LGYHEDFIEY LRGLTFTGSL YSMKEGELVF NNEPIMRVEA
     PLVEAQLIET ALLNIVNYQT LIATKAARIK GVIGDEVALE FGTRRAHEMD AAMWGARAAL
     IGGFSATSNV RAGKRFNIPV SGTHAHALVQ AYRDEYTAFK KYAETHKDCV FLVDTYDTLR
     SGMPNAIRVA KEFGDRINFI GIRLDSGDLA YLSKKARKML DEAGFTDAKV IASSDLDEHT
     IMNLKAQGAR IDVWGVGTKL ITAYDQPALG AVYKLVAIEE DGKMVDTIKI SSNPEKVTTP
     GRKKVYRIIN QSNHHSEGDY IALYDEQVND QKRLRMFHPV HTFISKFVTN FYAKDLHELI
     FEKGILCYQN PEISDIQQYV QDNLSLLWEE YKRISKPEEY PVDLSEDCWS NKMQRIHEVK
     SRLDEELEEE
//