ID G7W090_PAETH Unreviewed; 161 AA.
AC G7W090;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 03-APR-2013, entry version 12.
DE RecName: Full=N5-carboxyaminoimidazole ribonucleotide mutase;
DE Short=N5-CAIR mutase;
DE EC=5.4.99.18;
GN OrderedLocusNames=HPL003_11755;
OS Paenibacillus terrae (strain HPL-003).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Paenibacillaceae;
OC Paenibacillus.
OX NCBI_TaxID=985665;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HPL-003;
RA Shin S.H., Kim S., Kim J.Y.;
RT "Complete sequence of Paenibacillus terrae HPL-003.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HPL-003;
RA Shin S.H., Kim S., Kim J.Y.;
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Catalyzes the conversion of N5-carboxyaminoimidazole
CC ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole
CC ribonucleotide (CAIR) (By similarity).
CC -!- CATALYTIC ACTIVITY: 5-carboxyamino-1-(5-phospho-D-
CC ribosyl)imidazole = 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-
CC carboxylate.
CC -!- PATHWAY: Purine metabolism; IMP biosynthesis via de novo pathway;
CC 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-
CC amino-1-(5-phospho-D-ribosyl)imidazole (N5-CAIR route): step 2/2.
CC -!- SIMILARITY: Belongs to the AIR carboxylase family.
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DR EMBL; CP003107; AET59108.1; -; Genomic_DNA.
DR RefSeq; YP_005075331.1; NC_016641.1.
DR EnsemblBacteria; AET59108; AET59108; HPL003_11755.
DR GeneID; 11583651; -.
DR KEGG; pta:HPL003_11755; -.
DR KO; K01588; -.
DR OMA; KHACDIL; -.
DR UniPathway; UPA00074; UER00943.
DR GO; GO:0034023; F:5-(carboxyamino)imidazole ribonucleotide mutase activity; IEA:EC.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0006189; P:'de novo' IMP biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.40.50.7700; -; 1.
DR InterPro; IPR024694; N5-CAIR_mutase_PurE.
DR InterPro; IPR000031; N5-CAIR_Mutase_PurE_dom.
DR Pfam; PF00731; AIRC; 1.
DR PIRSF; PIRSF001338; AIR_carboxylase; 1.
DR SMART; SM01001; AIRC; 1.
DR SUPFAM; SSF52255; AIR_carboxyl; 1.
DR TIGRFAMs; TIGR01162; purE; 1.
PE 3: Inferred from homology;
KW Complete proteome; Isomerase; Purine biosynthesis; Transferase.
FT BINDING 11 11 Substrate (By similarity).
FT BINDING 14 14 Substrate (By similarity).
FT BINDING 41 41 Substrate (By similarity).
SQ SEQUENCE 161 AA; 16702 MW; 5ED13EF07864DCEC CRC64;
MSVQVAVIMG STSDWDTMQH ACAVLDELEI GYEKKVVSAH RTPDLMFRFA EEAAGRGLKV
IIAGAGGAAH LPGMVAAKTS LPVIGVPVQS KALNGLDSLL SIVQMPGGIP VATVAIGKAG
ATNAGLLAAQ ILGAFDEKIS QRVVARRDRI RDEVLEGSDS L
//
