ID G8R6A8_OWEHD Unreviewed; 417 AA.
AC G8R6A8;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 03-APR-2013, entry version 11.
DE RecName: Full=3-oxoacyl-[acyl-carrier-protein] synthase 2;
DE EC=2.3.1.179;
GN OrderedLocusNames=Oweho_2357;
OS Owenweeksia hongkongensis (strain DSM 17368 / JCM 12287 / NRRL
OS B-23963).
OC Bacteria; Bacteroidetes; Flavobacteriia; Flavobacteriales;
OC Cryomorphaceae; Owenweeksia.
OX NCBI_TaxID=926562;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17368 / JCM 12287 / NRRL B-23963;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Han J., Lapidus A., Bruce D., Goodwin L., Pitluck S.,
RA Peters L., Kyrpides N., Mavromatis K., Ivanova N., Mikhailova N.,
RA Held B., Detter J.C., Tapia R., Han C., Land M., Hauser L.,
RA Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Tindall B.,
RA Pomrenke H., Brambilla E.-M., Klenk H.-P., Eisen J.A.;
RT "The complete genome of Owenweeksia hongkongensis DSM 17368.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Catalyzes the condensation reaction of fatty acid
CC synthesis by the addition to an acyl acceptor of two carbons from
CC malonyl-ACP (By similarity).
CC -!- CATALYTIC ACTIVITY: (Z)-hexadec-11-enoyl-[acyl-carrier-protein] +
CC malonyl-[acyl-carrier-protein] = (Z)-3-oxooctadec-13-enoyl-[acyl-
CC carrier-protein] + CO(2) + [acyl-carrier-protein].
CC -!- PATHWAY: Lipid metabolism; fatty acid biosynthesis.
CC -!- SIMILARITY: Belongs to the beta-ketoacyl-ACP synthases family.
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DR EMBL; CP003156; AEV33328.1; -; Genomic_DNA.
DR RefSeq; YP_004989973.1; NC_016599.1.
DR EnsemblBacteria; AEV33328; AEV33328; Oweho_2357.
DR GeneID; 11631471; -.
DR KEGG; oho:Oweho_2357; -.
DR KO; K09458; -.
DR UniPathway; UPA00094; -.
DR GO; GO:0033817; F:beta-ketoacyl-acyl-carrier-protein synthase II activity; IEA:EC.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR017568; 3-oxoacyl-ACP_synth-2.
DR InterPro; IPR018201; Ketoacyl_synth_AS.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR016038; Thiolase-like_subgr.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR PIRSF; PIRSF000447; KAS_II; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR TIGRFAMs; TIGR03150; fabF; 1.
DR PROSITE; PS00606; B_KETOACYL_SYNTHASE; 1.
PE 3: Inferred from homology;
KW Acyltransferase; Complete proteome; Fatty acid biosynthesis;
KW Lipid biosynthesis; Transferase.
SQ SEQUENCE 417 AA; 44097 MW; 78B5F04A3B1C7F05 CRC64;
MELKRVVVTG VGAISPIGNT AEETWQNMLN GKSGAAPITL FDASKFKTQF ACEVKNFDAA
EYFDRKEARK MDRFSHFAIA VADEALKNSG LIEHPSFDPD RVGVIWGSGI GGLDTFQQES
IAFGKGDGTP RFNPFFIPKM IADIAGGHIS IKYGLRGPNF TTVSACASST NAMIDAFNYI
RLGMMDACVT GGSEAAITEA GMGGFNAMHA LSTRNDSPET ASRPFDKDRD GFVLGEGGAC
IILEEYESAK KRGANILAEV IGAGLSADAH HITAPHPEGL GAKAVMENAL KDAGIKAQEI
GYINVHGTST PLGDVAELKA IKAIFGDDAY DLNISSTKSM TGHLLGAAGA LEAIACIMAV
KENIVPPTIN HVTDDPNIDS KLNLTFGKAQ EREVNVALSN TFGFGGHNAS VIVKKHI
//
