ID G8S3B1_ACTS5 Unreviewed; 1073 AA.
AC G8S3B1;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Ribonuclease E {ECO:0000313|EMBL:AEV82271.1};
DE EC=3.1.26.12 {ECO:0000313|EMBL:AEV82271.1};
GN OrderedLocusNames=ACPL_1374 {ECO:0000313|EMBL:AEV82271.1};
OS Actinoplanes sp. (strain ATCC 31044 / CBS 674.73 / SE50/110).
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Actinoplanes.
OX NCBI_TaxID=134676 {ECO:0000313|EMBL:AEV82271.1, ECO:0000313|Proteomes:UP000005440};
RN [1] {ECO:0000313|Proteomes:UP000005440}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 31044 / CBS 674.73 / SE50/110
RC {ECO:0000313|Proteomes:UP000005440};
RA Schwientek P., Szczepanowski R., Kalinowski J., Klein A., Selber K.,
RA Wehmeier U.F., Stoye J., Puehler A.;
RT "The complete genome sequence of the acarbose producer Actinoplanes sp.
RT SE50/110.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
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DR EMBL; CP003170; AEV82271.1; -; Genomic_DNA.
DR RefSeq; WP_014688344.1; NZ_LT827010.1.
DR AlphaFoldDB; G8S3B1; -.
DR STRING; 134676.ACPL_1374; -.
DR KEGG; ase:ACPL_1374; -.
DR PATRIC; fig|134676.3.peg.1271; -.
DR eggNOG; COG1530; Bacteria.
DR HOGENOM; CLU_003468_2_2_11; -.
DR OrthoDB; 9804278at2; -.
DR Proteomes; UP000005440; Chromosome.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004540; F:RNA nuclease activity; IEA:InterPro.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR CDD; cd04453; S1_RNase_E; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR019307; RNA-bd_AU-1/RNase_E/G.
DR InterPro; IPR004659; RNase_E/G.
DR InterPro; IPR003029; S1_domain.
DR NCBIfam; TIGR00757; RNaseEG; 1.
DR PANTHER; PTHR30001; RIBONUCLEASE; 1.
DR PANTHER; PTHR30001:SF0; RIBONUCLEASE G; 1.
DR Pfam; PF10150; RNase_E_G; 1.
DR SMART; SM00316; S1; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR PROSITE; PS50126; S1; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:AEV82271.1};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000005440};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT DOMAIN 501..584
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT REGION 1..448
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 896..929
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1000..1073
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 131..155
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 165..183
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 265..283
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 298..320
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 348..376
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 430..448
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1007..1021
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1073 AA; 114670 MW; 4072BDDE52C8BC50 CRC64;
MLDNEPPVTL GEQGGERDGA ATPPVDAATG TTPARRTRAP RRKAAAPGAE EVAETAAAAP
AEVVEPTPAP VKKATRSRRK VAEPAPEAAP AAAAEEAAAE AVAETAEKPA PVKKATRSRR
KVAAPPAEQL EIPPAAEPSP APVAPVAPPE SPEVPIVGIL PLDDDFLEPA EEEPAEEQPA
EEQAAAEAEP AGQRPARARK APLPPPVLFM PPEATEVAPA PVSRRRRPVT DPLAPVATAP
AEQPAEPAAA EPVTAEPVTA EAAEEPAEGT RRSRRRRRGA AEEPAPEPVA AAAEQPVLDE
IDESDESADD AEDGVEDDGD DDEAGGRRRR RRGRRGRGRG KGPSDEADDA DLDAEESEGE
AEAAHDEEAE DEESEDGEGG VTRRRRRRRR KGSSGDGETG GIEDGVHTVV RVREPRRSDE
VQGVSGSTRL EAKRQRRRDG REQRRTRPPI LSESEFLARR EAVDRVMVVR QKPDRIQIAV
LEDGVLVEHY VARATSGTMV GNVYLGKVQN VLPSMEAAFV DVGRGRNAVL YAGEVNWDAT
GLEGRARSIE QALRSGDSVL VQVTKDPIGH KGARLTSHIA LSGRHLVYVP NGNASGISRK
LPDNERKRLR DILKKLVPDG AGVIVRTAAE GASEDELARD VKRLQAQWED IQARAAEGNA
PRALSEEPDL VIRVVRDLFN EDFRELIVQG EQAYAEVENY LHSVSPDLVE RLHRHVGVGD
VFAENRIDEQ ILKGLDRKVF LPSGGHLVID RTEAMTVVDV NTGKYTGAGG NLEETVTRNN
LEAAEEIVRQ LRLRDLGGIV VIDFIDMVLE SNRELVLRRL TECLGRDRTK HQVTEITSLG
LVQMTRKRIG AGLLEAFSET CDHCKGRGVI IHHEPVPERR SNGGGAAPAA TQVKAVAAAA
RTEAPPAQPA AATSGRSRRR RGGGDTPPVE VAEVVEPITE QAGPITEEAG PAAEVAELPA
IPEVPGTPVA PVAAAAPVAG SGVIRSGVVR PAQPVVTSSA DADDYDISGY DLSRYETEEA
DGAAYEADTE PLRLVGSDDP DAADEDEDDD ESVGVGTGRR RSRRSGARRR TRP
//
