ID H0Q5T9_9RHOO Unreviewed; 496 AA.
AC H0Q5T9;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 24-JAN-2024, entry version 46.
DE SubName: Full=NAD-dependent aldehyde dehydrogenase {ECO:0000313|EMBL:BAL27352.1};
GN Name=aldA {ECO:0000313|EMBL:BAL27352.1};
GN ORFNames=AZKH_p0469 {ECO:0000313|EMBL:BAL27352.1};
OS Azoarcus sp. KH32C.
OG Plasmid pAZKH {ECO:0000313|EMBL:BAL27352.1,
OG ECO:0000313|Proteomes:UP000007106}.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales; Zoogloeaceae;
OC Azoarcus.
OX NCBI_TaxID=748247 {ECO:0000313|EMBL:BAL27352.1, ECO:0000313|Proteomes:UP000007106};
RN [1] {ECO:0000313|EMBL:BAL27352.1, ECO:0000313|Proteomes:UP000007106}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KH32C {ECO:0000313|EMBL:BAL27352.1,
RC ECO:0000313|Proteomes:UP000007106};
RC PLASMID=Plasmid pAZKH {ECO:0000313|Proteomes:UP000007106};
RA Nishizawa T., Tago T., Oshima K., Hattori M., Ishii S., Otsuka S.,
RA Senoo K.;
RT "Complete genome sequence of Azoarcus sp. KH32C.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|RuleBase:RU003345}.
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DR EMBL; AP012305; BAL27352.1; -; Genomic_DNA.
DR RefSeq; WP_015452125.1; NC_020548.1.
DR AlphaFoldDB; H0Q5T9; -.
DR KEGG; aza:AZKH_p0469; -.
DR PATRIC; fig|748247.4.peg.5042; -.
DR eggNOG; COG1012; Bacteria.
DR HOGENOM; CLU_005391_1_0_4; -.
DR OrthoDB; 6187633at2; -.
DR Proteomes; UP000007106; Plasmid pAZKH.
DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd07114; ALDH_DhaS; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR PANTHER; PTHR11699:SF211; ALDEHYDE DEHYDROGENASE FAMILY 16 MEMBER A1; 1.
DR PANTHER; PTHR11699; ALDEHYDE DEHYDROGENASE-RELATED; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003345}; Plasmid {ECO:0000313|EMBL:BAL27352.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000007106}.
FT DOMAIN 22..481
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 256
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ SEQUENCE 496 AA; 53299 MW; 756ECCDF63010E38 CRC64;
MSRLDSLPKY GQFINGAEVP PASGEYFPTE NPYSGEAWAL IGRGGKADAD AAVAAAHAAF
EEGVWASLSA SERGKLMRKL ADLIVANAEH LAEIERRDNG KLAAEVVAQV KYMGDYFHYY
AGLADKIESH VIPTDKKGVF CYTKYEAKGV VVIITPWNSP LTLTSWKLAP ALAAGCTVVI
KPSEFTSASA IEFAKLFAQA GFPPGVVNVV TGFGHEVGAP LVEHPDTAHI GFTGGEIAGQ
KIYEAAARGL KTVTLELGGK SPNIVFDDAD LDQAVKGIVS GVFAASGQTC QAGSRLLVQE
SIHDEVVRRL VEFVSTAKIG DPSQLDTQVG PIATRPQFEK IMSYIQIAKD EGAKCVLGGK
SRPDLGAGQF VEPTIFTGVN NKMRIAQEEV FGPVLCVIPF KDEKDAVRIG NDVLYGLAGA
VWTKSLHRAM YVTDKLKAGT VWVNNYRATS YTSPFGGYKR SGIGRESGAD AIKEYLETKC
VWISTDLDVP NPFIRR
//
