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Database: UniProt/TrEMBL
Entry: H2A7S4_STRMD
LinkDB: H2A7S4_STRMD
Original site: H2A7S4_STRMD 
ID   H2A7S4_STRMD            Unreviewed;       941 AA.
AC   H2A7S4;
DT   21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT   21-MAR-2012, sequence version 1.
DT   22-NOV-2017, entry version 37.
DE   RecName: Full=Phosphoenolpyruvate carboxylase {ECO:0000256|HAMAP-Rule:MF_00595, ECO:0000256|SAAS:SAAS00946768};
DE            Short=PEPC {ECO:0000256|HAMAP-Rule:MF_00595};
DE            Short=PEPCase {ECO:0000256|HAMAP-Rule:MF_00595};
DE            EC=4.1.1.31 {ECO:0000256|HAMAP-Rule:MF_00595, ECO:0000256|SAAS:SAAS00946768};
GN   Name=ppc {ECO:0000256|HAMAP-Rule:MF_00595,
GN   ECO:0000313|EMBL:CCF02816.1};
GN   OrderedLocusNames=SMA_1525 {ECO:0000313|EMBL:CCF02816.1};
OS   Streptococcus macedonicus (strain ACA-DC 198).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=1116231 {ECO:0000313|EMBL:CCF02816.1, ECO:0000313|Proteomes:UP000007152};
RN   [1] {ECO:0000313|EMBL:CCF02816.1, ECO:0000313|Proteomes:UP000007152}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ACA-DC 198 {ECO:0000313|EMBL:CCF02816.1,
RC   ECO:0000313|Proteomes:UP000007152};
RX   PubMed=22408241; DOI=10.1128/JB.06804-11;
RA   Papadimitriou K., Ferreira S., Papandreou N.C., Mavrogonatou E.,
RA   Supply P., Pot B., Tsakalidou E.;
RT   "Complete Genome Sequence of the Dairy Isolate Streptococcus
RT   macedonicus ACA-DC 198.";
RL   J. Bacteriol. 194:1838-1839(2012).
CC   -!- FUNCTION: Forms oxaloacetate, a four-carbon dicarboxylic acid
CC       source for the tricarboxylic acid cycle. {ECO:0000256|HAMAP-
CC       Rule:MF_00595, ECO:0000256|SAAS:SAAS00946761}.
CC   -!- CATALYTIC ACTIVITY: Phosphate + oxaloacetate = H(2)O +
CC       phosphoenolpyruvate + HCO(3)(-). {ECO:0000256|HAMAP-Rule:MF_00595,
CC       ECO:0000256|SAAS:SAAS00946751}.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000256|HAMAP-
CC         Rule:MF_00595, ECO:0000256|SAAS:SAAS00946766};
CC   -!- SUBUNIT: Homotetramer. {ECO:0000256|HAMAP-Rule:MF_00595}.
CC   -!- SIMILARITY: Belongs to the PEPCase type 1 family.
CC       {ECO:0000256|HAMAP-Rule:MF_00595, ECO:0000256|SAAS:SAAS00946753}.
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DR   EMBL; HE613569; CCF02816.1; -; Genomic_DNA.
DR   RefSeq; WP_014294971.1; NC_016749.1.
DR   STRING; 1116231.SMA_1525; -.
DR   EnsemblBacteria; CCF02816; CCF02816; SMA_1525.
DR   KEGG; smn:SMA_1525; -.
DR   eggNOG; COG2352; LUCA.
DR   KO; K01595; -.
DR   OMA; PWVFGWT; -.
DR   OrthoDB; POG091H040O; -.
DR   Proteomes; UP000007152; Chromosome.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0008964; F:phosphoenolpyruvate carboxylase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0015977; P:carbon fixation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006107; P:oxaloacetate metabolic process; IEA:UniProtKB-UniRule.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR   HAMAP; MF_00595; PEPcase_type1; 1.
DR   InterPro; IPR021135; PEP_COase.
DR   InterPro; IPR022805; PEP_COase_bac/pln-type.
DR   InterPro; IPR018129; PEP_COase_Lys_AS.
DR   InterPro; IPR033129; PEPCASE_His_AS.
DR   InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR   PANTHER; PTHR30523; PTHR30523; 1.
DR   Pfam; PF00311; PEPcase; 1.
DR   PRINTS; PR00150; PEPCARBXLASE.
DR   SUPFAM; SSF51621; SSF51621; 2.
DR   PROSITE; PS00781; PEPCASE_1; 1.
DR   PROSITE; PS00393; PEPCASE_2; 1.
PE   3: Inferred from homology;
KW   Carbon dioxide fixation {ECO:0000256|HAMAP-Rule:MF_00595,
KW   ECO:0000256|SAAS:SAAS00946757};
KW   Complete proteome {ECO:0000313|Proteomes:UP000007152};
KW   Lyase {ECO:0000256|HAMAP-Rule:MF_00595, ECO:0000256|SAAS:SAAS00946754,
KW   ECO:0000313|EMBL:CCF02816.1};
KW   Magnesium {ECO:0000256|HAMAP-Rule:MF_00595,
KW   ECO:0000256|SAAS:SAAS00946750};
KW   Pyruvate {ECO:0000313|EMBL:CCF02816.1}.
FT   ACT_SITE    138    138       {ECO:0000256|HAMAP-Rule:MF_00595,
FT                                ECO:0000256|PROSITE-ProRule:PRU10111}.
FT   ACT_SITE    604    604       {ECO:0000256|HAMAP-Rule:MF_00595,
FT                                ECO:0000256|PROSITE-ProRule:PRU10112}.
SQ   SEQUENCE   941 AA;  107390 MW;  D29E3CDA83B217B5 CRC64;
     MTIKKLENNS TQSIITEEVK ILKGLLDEIT HQMVGDEVFA KIQNIVELSA SDEYVKLEKL
     VVQLTNDEMV VVSRYFSILP LLINISEDVD FAYEINYQNN TNQDYLGKLS LTVDMVSESE
     NSKEILENVN VVPVLTAHPT QVQRKTVLEL TNHIHDLLRK YRDVRAGVVN RDKWYTDLRR
     YIEIIMQTDI IREKKLKVKN EITNVMEYYN TSLIQAITKL TSEYKRLAAE KGIDLENPKP
     ITMGMWIGGD RDGNPYVTAE TLRLSATVQS EVIINYYIEK LTALYRTFSL STTLTNISPE
     VEKLAELSSD KSIYRENEPY RKAFNYIQSK LIQTLIELKA NTAISQGVLE GSNNISSDVC
     TSTKNAGVIT KYLQTKFSKV SSELQEEIPS YKTAKEFKDD LFIIKQSLLD NGDDALLTGD
     FSELLQAVDV FGFYLAMIDM RQDSSVNEAC VAELLKSANI IEDYSSLSEE EKVKVLLKEL
     QEDPRTLSST NAEKSEQLQK ELAIFQTARY LKDKLGDEVI KQHIISHTES VSDMFELAIM
     LKEVGLLDNQ TARVQIVPLF ETIEDLENSR AIMEEYLDYD IVRRWVSASK GYQEIMLGYS
     DSNKDGGYLS SVWTLYKAQN ELTRIGSERG IKVTFIHGRG GTVGRGGGPS YEAITSQPFG
     SIKDRIRLTE QGEIIENKYG NKDVAYYNLE MLVSATIDRI VTRMITNPDE IDDFRATMDG
     IVTYSNGVYR DLVFGNPHFY DYFFEATPIK EVSSLNIGSR PAARKTITEI SGLRAIPWVF
     SWSQSRIMFP GWYGVGSAFK NFIDAEEGNL AKLQHMYEKW PFFHSLLSNV DMVLSKSNMN
     IAFQYAQLAE SEEVRDVFNT ILDEWQLTKN VILAIEKHQD LLEENPSLKA SLDYRLPYFN
     VLNYIQIELI KRLRHEELDE DYEKLIHTTI NGIATGLRNS G
//
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