ID H2NV43_PONAB Unreviewed; 670 AA.
AC H2NV43; A0A2J8XZ78;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 3.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=LRRC45 isoform 1 {ECO:0000313|EMBL:PNJ87334.1};
DE SubName: Full=Leucine rich repeat containing 45 {ECO:0000313|Ensembl:ENSPPYP00000009836.3};
GN Name=LRRC45 {ECO:0000313|Ensembl:ENSPPYP00000009836.3};
GN ORFNames=CR201_G0021186 {ECO:0000313|EMBL:PNJ87334.1};
OS Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pongo.
OX NCBI_TaxID=9601 {ECO:0000313|Ensembl:ENSPPYP00000009836.3, ECO:0000313|Proteomes:UP000001595};
RN [1] {ECO:0000313|Ensembl:ENSPPYP00000009836.3, ECO:0000313|Proteomes:UP000001595}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Wilson R.K., Mardis E.;
RT "A 6x draft sequence assembly of the Pongo pygmaeus abelii genome.";
RL Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:PNJ87334.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Susie {ECO:0000313|EMBL:PNJ87334.1};
RA Pollen A., Hastie A., Hormozdiari F., Dougherty M., Liu R., Chaisson M.,
RA Hoppe E., Hill C., Pang A., Hillier L., Baker C., Armstrong J.,
RA Shendure J., Paten B., Wilson R., Chao H., Schneider V., Ventura M.,
RA Kronenberg Z., Murali S., Gordon D., Cantsilieris S., Munson K., Nelson B.,
RA Raja A., Underwood J., Diekhans M., Fiddes I., Haussler D., Eichler E.;
RT "High-resolution comparative analysis of great ape genomes.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSPPYP00000009836.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; NDHI03003285; PNJ87334.1; -; Genomic_DNA.
DR STRING; 9601.ENSPPYP00000009836; -.
DR Ensembl; ENSPPYT00000010227.3; ENSPPYP00000009836.3; ENSPPYG00000008762.3.
DR eggNOG; KOG4308; Eukaryota.
DR GeneTree; ENSGT00940000154003; -.
DR HOGENOM; CLU_015877_0_0_1; -.
DR OMA; EVDHMTR; -.
DR OrthoDB; 2907835at2759; -.
DR TreeFam; TF330983; -.
DR Proteomes; UP000001595; Chromosome 17.
DR GO; GO:0005813; C:centrosome; IEA:Ensembl.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR23170:SF3; LEUCINE-RICH REPEAT-CONTAINING PROTEIN 45; 1.
DR PANTHER; PTHR23170; NY-REN-58 ANTIGEN; 1.
DR Pfam; PF13516; LRR_6; 3.
DR SMART; SM00368; LRR_RI; 5.
DR SUPFAM; SSF52047; RNI-like; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Reference proteome {ECO:0000313|Proteomes:UP000001595}.
FT COILED 298..642
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 670 AA; 75846 MW; BF7775EAFB601B96 CRC64;
MEEFRRSYSR LCRESGAEPQ EAVLQQLHQL PRGRLDLATQ SLTVETCRAL GKLLPRETLC
TELVLSDCML SEEGATLLLR GLCANTVLRF LDLKGNNLRA AGAEALGKLL QQNKSIQSLT
LEWNSLGTWD DAFATFCGGL AANGALQQLD LRNNQISHKG AEELALALKG NTTLQQLDLR
WNNVGLLGGR ALMNCLPSNR TLWRLDLAGN NIPGDVLRAV EQAMGHSQDR LTTFQENQAR
THVLSKEVQH LREEKSKQFL DLMETIDKQR EEMAKSSRAS AAHVGQLQEA LNERHSIINA
LKAKLQMTEA ALALSEQKAQ DLGELLATAE QEQLSLSQRQ AKELKLEQQE AAERESKLLR
DLSAANEKNL LLQNQVDELE RKFRCQQEQL FQTRQELTSM SAELKMRAIQ AEERLDMEKR
RCRQSLEDSE SLRIKEVEHM TRHLEESEKA MQERVQRLEA ARLSLEEELS RVKAAALSER
GQAEEELIKA KSQARLEEQQ RLAHLEDKLR LLAQARDEAQ GACLQQKQVV ADSQTRASQL
GLQVEGLRRR LEELQQELSL KDQERVAEVS RVRVELQEQN GRLQAELAAQ EALREKAAAL
ERQLKVMASD HREALLDRES ENASLREKLR LREAEIARIR DEEAQRASFL QNAVLAYVQG
SPVRTLSPPK
//
