ID H8HJ47_MYCTU Unreviewed; 254 AA.
AC H8HJ47;
DT 16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT 16-MAY-2012, sequence version 1.
DT 01-MAY-2013, entry version 11.
DE RecName: Full=Pseudouridine synthase;
DE EC=5.4.99.-;
GN ORFNames=MRGA327_10615;
OS Mycobacterium tuberculosis RGTB327.
OC Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC Corynebacterineae; Mycobacteriaceae; Mycobacterium;
OC Mycobacterium tuberculosis complex.
OX NCBI_TaxID=1091500;
RN [1]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=RGTB327;
RX PubMed=22843573; DOI=10.1128/JB.00453-12;
RA Madhavilatha G.K., Joseph B.V., Paul L.K., Kumar R.A., Hariharan R.,
RA Mundayoor S.;
RT "Whole-Genome Sequences of Two Clinical Isolates of Mycobacterium
RT tuberculosis from Kerala, South India.";
RL J. Bacteriol. 194:4430-4430(2012).
RN [2]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=RGTB327;
RA Madhavilatha K.G., Joseph B.V., Paul L.K., Kumar A.R., Hariharan R.,
RA Mundayoor S.;
RL Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the pseudouridine synthase rsuA family.
CC -!- SIMILARITY: Contains 1 S4 RNA-binding domain.
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DR EMBL; CP003233; AFE16604.1; -; Genomic_DNA.
DR RefSeq; YP_005360353.1; NC_017026.1.
DR ProteinModelPortal; H8HJ47; -.
DR SMR; H8HJ47; 14-248.
DR EnsemblBacteria; AFE16604; AFE16604; MRGA327_10615.
DR GeneID; 11959119; -.
DR KEGG; mtg:MRGA327_10615; -.
DR KO; K06178; -.
DR OMA; CEDLIFR; -.
DR GO; GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0001522; P:pseudouridine synthesis; IEA:InterPro.
DR Gene3D; 3.10.290.10; -; 1.
DR InterPro; IPR020103; PsdUridine_synth_cat_dom.
DR InterPro; IPR000748; PsdUridine_synth_RsuA/RluB/E/F.
DR InterPro; IPR018496; PsdUridine_synth_RsuA/RluB_CS.
DR InterPro; IPR006145; PsdUridine_synth_RsuA/RluD.
DR InterPro; IPR002942; S4_RNA-bd.
DR Pfam; PF00849; PseudoU_synth_2; 1.
DR Pfam; PF01479; S4; 1.
DR SMART; SM00363; S4; 1.
DR SUPFAM; SSF55120; PsdUridine_synth_cat_dom; 1.
DR TIGRFAMs; TIGR00093; TIGR00093; 1.
DR PROSITE; PS01149; PSI_RSU; 1.
DR PROSITE; PS50889; S4; 1.
PE 3: Inferred from homology;
KW Isomerase; RNA-binding.
SQ SEQUENCE 254 AA; 27597 MW; EB2D95D7CF0FDF26 CRC64;
MMAEPEESRE PRGIRLQKVL SQAGIASRRA AEKMIVDGRV EVDGHVVTEL GTRVDPQVAV
VRVDGARVVL DDSLVYLALN KPRGMHSTMS DDRGRPCIGD LIERKVRGTK KLFHVGRLDA
DTEGLMLLTN DGELAHRLMH PSHEVPKTYL ATVTGSVPRG LGRTLRAGIE LDDGPAFVDD
FAVVDAIPGK TLVRVTLHEG RNRIVRRLLA AAGFPVEALV RTDIGAVSLG KQRPGSVRAL
RSNEIGQLYQ AVGL
//
