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Database: UniProt/TrEMBL
Entry: I1LKU7_SOYBN
LinkDB: I1LKU7_SOYBN
Original site: I1LKU7_SOYBN 
ID   I1LKU7_SOYBN            Unreviewed;       429 AA.
AC   I1LKU7;
DT   13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT   09-JAN-2013, sequence version 2.
DT   28-MAR-2018, entry version 40.
DE   RecName: Full=Histone deacetylase {ECO:0000256|PIRNR:PIRNR037913, ECO:0000256|SAAS:SAAS00894283};
DE            EC=3.5.1.98 {ECO:0000256|PIRNR:PIRNR037913, ECO:0000256|SAAS:SAAS00894283};
GN   Name=100795845 {ECO:0000313|EnsemblPlants:KRH30495};
GN   ORFNames=GLYMA_11G187800 {ECO:0000313|EMBL:KRH30495.1};
OS   Glycine max (Soybean) (Glycine hispida).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae;
OC   Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae;
OC   Phaseoleae; Glycine; Soja.
OX   NCBI_TaxID=3847 {ECO:0000313|EMBL:KRH30495.1};
RN   [1] {ECO:0000313|EnsemblPlants:KRH30495}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Williams 82 {ECO:0000313|EnsemblPlants:KRH30495};
RX   PubMed=16247559; DOI=10.1007/s11103-005-8882-0;
RA   Saski C., Lee S.-B., Daniell H., Wood T.C., Tomkins J., Kim H.-G.,
RA   Jansen R.K.;
RT   "Complete chloroplast genome sequence of Glycine max and comparative
RT   analyses with other legume genomes.";
RL   Plant Mol. Biol. 59:309-322(2005).
RN   [2] {ECO:0000313|EMBL:KRH30495.1, ECO:0000313|Proteomes:UP000008827}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=cv. Williams 82 {ECO:0000313|Proteomes:UP000008827};
RC   TISSUE=Callus {ECO:0000313|EMBL:KRH30495.1};
RX   PubMed=20075913; DOI=10.1038/nature08670;
RA   Schmutz J., Cannon S.B., Schlueter J., Ma J., Mitros T., Nelson W.,
RA   Hyten D.L., Song Q., Thelen J.J., Cheng J., Xu D., Hellsten U.,
RA   May G.D., Yu Y., Sakurai T., Umezawa T., Bhattacharyya M.K.,
RA   Sandhu D., Valliyodan B., Lindquist E., Peto M., Grant D., Shu S.,
RA   Goodstein D., Barry K., Futrell-Griggs M., Abernathy B., Du J.,
RA   Tian Z., Zhu L., Gill N., Joshi T., Libault M., Sethuraman A.,
RA   Zhang X.-C., Shinozaki K., Nguyen H.T., Wing R.A., Cregan P.,
RA   Specht J., Grimwood J., Rokhsar D., Stacey G., Shoemaker R.C.,
RA   Jackson S.A.;
RT   "Genome sequence of the palaeopolyploid soybean.";
RL   Nature 463:178-183(2010).
RN   [3] {ECO:0000313|EMBL:KRH30495.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Callus {ECO:0000313|EMBL:KRH30495.1};
RA   Hoefler B.C., Straight P.D.;
RL   Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
RN   [4] {ECO:0000313|EnsemblPlants:KRH30495}
RP   IDENTIFICATION.
RC   STRAIN=Williams 82 {ECO:0000313|EnsemblPlants:KRH30495};
RG   EnsemblPlants;
RL   Submitted (FEB-2018) to UniProtKB.
CC   -!- CATALYTIC ACTIVITY: Hydrolysis of an N(6)-acetyl-lysine residue of
CC       a histone to yield a deacetylated histone.
CC       {ECO:0000256|PIRNR:PIRNR037913, ECO:0000256|SAAS:SAAS00894227}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PIRNR:PIRNR037913,
CC       ECO:0000256|SAAS:SAAS00894298}.
CC   -!- SIMILARITY: Belongs to the histone deacetylase family. HD Type 1
CC       subfamily. {ECO:0000256|PIRNR:PIRNR037913}.
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DR   EMBL; ACUP02007026; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CM000844; KRH30495.1; -; Genomic_DNA.
DR   RefSeq; XP_003538135.1; XM_003538087.3.
DR   STRING; 3847.GLYMA11G19290.1; -.
DR   EnsemblPlants; KRH30495; KRH30495; GLYMA_11G187800.
DR   GeneID; 100795845; -.
DR   KEGG; gmx:100795845; -.
DR   KO; K06067; -.
DR   OMA; HAMKPQR; -.
DR   OrthoDB; EOG093609CH; -.
DR   Proteomes; UP000008827; Chromosome 11.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:UniProtKB-EC.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.800.20; -; 1.
DR   InterPro; IPR000286; His_deacetylse.
DR   InterPro; IPR003084; His_deacetylse_1.
DR   InterPro; IPR023801; His_deacetylse_dom.
DR   InterPro; IPR037138; His_deacetylse_dom_sf.
DR   InterPro; IPR023696; Ureohydrolase_dom_sf.
DR   PANTHER; PTHR10625; PTHR10625; 1.
DR   Pfam; PF00850; Hist_deacetyl; 1.
DR   PIRSF; PIRSF037913; His_deacetylse_1; 1.
DR   PRINTS; PR01270; HDASUPER.
DR   PRINTS; PR01271; HISDACETLASE.
DR   SUPFAM; SSF52768; SSF52768; 1.
PE   3: Inferred from homology;
KW   Chromatin regulator {ECO:0000256|PIRNR:PIRNR037913,
KW   ECO:0000256|SAAS:SAAS00894233};
KW   Complete proteome {ECO:0000313|Proteomes:UP000008827};
KW   Hydrolase {ECO:0000256|PIRNR:PIRNR037913,
KW   ECO:0000256|SAAS:SAAS00870288};
KW   Metal-binding {ECO:0000256|PIRSR:PIRSR037913-3};
KW   Nucleus {ECO:0000256|PIRNR:PIRNR037913,
KW   ECO:0000256|SAAS:SAAS00894277};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008827};
KW   Transcription {ECO:0000256|PIRNR:PIRNR037913,
KW   ECO:0000256|SAAS:SAAS00894309};
KW   Transcription regulation {ECO:0000256|PIRNR:PIRNR037913,
KW   ECO:0000256|SAAS:SAAS00894290}.
FT   DOMAIN       24    315       Hist_deacetyl. {ECO:0000259|Pfam:
FT                                PF00850}.
FT   ACT_SITE    137    137       Proton acceptor. {ECO:0000256|PIRSR:
FT                                PIRSR037913-1}.
FT   METAL       172    172       Divalent metal cation.
FT                                {ECO:0000256|PIRSR:PIRSR037913-3}.
FT   METAL       174    174       Divalent metal cation.
FT                                {ECO:0000256|PIRSR:PIRSR037913-3}.
FT   METAL       261    261       Divalent metal cation.
FT                                {ECO:0000256|PIRSR:PIRSR037913-3}.
FT   BINDING      95     95       Substrate. {ECO:0000256|PIRSR:
FT                                PIRSR037913-2}.
FT   BINDING     145    145       Substrate; via carbonyl oxygen.
FT                                {ECO:0000256|PIRSR:PIRSR037913-2}.
FT   BINDING     300    300       Substrate. {ECO:0000256|PIRSR:
FT                                PIRSR037913-2}.
SQ   SEQUENCE   429 AA;  48948 MW;  CEA102A9739A6DD1 CRC64;
     MPSKDKIAYF YDGDVGSVYF GAKHPMKPHR LCMTHHLVLS YDLHKKMEIY RPHKAYPVEL
     AQFHSADYVE FLNRITPDTQ HLFLKELTKY NLGEDCPVFD NLFEFCQIYA GGTIDAARRL
     NNQLCDIAIN WAGGLHHAKK CEASGFCYIN DLVLGILELL KYHARVLYID IDVHHGDGVE
     EAFYFTDRVM TVSFHKYGDL FFPGTGDAKE IGEREGKFYA INVPLKDGID DSSFTRLFKT
     IISKVLETYQ PGAIVLQCGA DSLAGDRLGC FNLSIDGHAE CVSFVKRFNL PLLVTGGGGY
     TKENVARCWT VETGVLLDTE LPNEIPENDY IKYFAPEFSL KIPNGQIENL NSKSYLSTIK
     MQVLENLRCI QHAPSVQMQE VPPDFYIPEF DEDEQNPDER LDQHTQDKHI QRDDEYYDGD
     NDNDQMDVS
//
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