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Database: UniProt/TrEMBL
Entry: J7L7K2_NOCAA
LinkDB: J7L7K2_NOCAA
Original site: J7L7K2_NOCAA 
ID   J7L7K2_NOCAA            Unreviewed;       876 AA.
AC   J7L7K2;
DT   31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   31-OCT-2012, sequence version 1.
DT   07-JUN-2017, entry version 31.
DE   SubName: Full=Methylmalonate-semialdehyde dehydrogenase {ECO:0000313|EMBL:AFR08661.1};
DE            EC=1.2.1.27 {ECO:0000313|EMBL:AFR08661.1};
GN   Name=mmsA {ECO:0000313|EMBL:AFR08661.1};
GN   OrderedLocusNames=B005_0839 {ECO:0000313|EMBL:AFR08661.1};
OS   Nocardiopsis alba (strain ATCC BAA-2165 / BE74).
OC   Bacteria; Actinobacteria; Streptosporangiales; Nocardiopsaceae;
OC   Nocardiopsis.
OX   NCBI_TaxID=1205910 {ECO:0000313|EMBL:AFR08661.1, ECO:0000313|Proteomes:UP000003779};
RN   [1] {ECO:0000313|Proteomes:UP000003779}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-2165 / BE74 {ECO:0000313|Proteomes:UP000003779};
RA   Qiao J., Chen L., Li Y., Wang J., Zhang W., Chen S.;
RT   "Whole-genome sequence of Nocardiopsis alba strain ATCC BAA-2165
RT   associated with honeybees.";
RL   Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP003788; AFR08661.1; -; Genomic_DNA.
DR   ProteinModelPortal; J7L7K2; -.
DR   EnsemblBacteria; AFR08661; AFR08661; B005_0839.
DR   KEGG; nal:B005_0839; -.
DR   PATRIC; fig|1205910.3.peg.791; -.
DR   KO; K00140; -.
DR   OrthoDB; POG091H0B1P; -.
DR   Proteomes; UP000003779; Chromosome.
DR   GO; GO:0004491; F:methylmalonate-semialdehyde dehydrogenase (acylating) activity; IEA:UniProtKB-EC.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0008483; F:transaminase activity; IEA:InterPro.
DR   CDD; cd07085; ALDH_F6_MMSDH; 1.
DR   CDD; cd00610; OAT_like; 1.
DR   Gene3D; 3.40.605.10; -; 1.
DR   Gene3D; 3.40.640.10; -; 1.
DR   Gene3D; 3.90.1150.10; -; 2.
DR   InterPro; IPR016161; Ald_DH/histidinol_DH.
DR   InterPro; IPR016160; Ald_DH_CS_CYS.
DR   InterPro; IPR016162; Ald_DH_N.
DR   InterPro; IPR015590; Aldehyde_DH_dom.
DR   InterPro; IPR005814; Aminotrans_3.
DR   InterPro; IPR010061; MeMal-semiAld_DH.
DR   InterPro; IPR034322; MeMal-semiAld_DH_cyt.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major_sub1.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_sub2.
DR   PANTHER; PTHR43866; PTHR43866; 1.
DR   PANTHER; PTHR43866:SF1; PTHR43866:SF1; 1.
DR   Pfam; PF00171; Aldedh; 1.
DR   Pfam; PF00202; Aminotran_3; 1.
DR   SUPFAM; SSF53383; SSF53383; 1.
DR   SUPFAM; SSF53720; SSF53720; 1.
DR   TIGRFAMs; TIGR01722; MMSDH; 1.
DR   PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000003779};
KW   Oxidoreductase {ECO:0000313|EMBL:AFR08661.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000003779}.
FT   DOMAIN      412    855       Aldedh. {ECO:0000259|Pfam:PF00171}.
SQ   SEQUENCE   876 AA;  92907 MW;  8D64A7859B040FC5 CRC64;
     MSELLSRHRA VMPSWSPLYY ESPLEIVSGK GSRVTDAEGR TYLDFFTGIV TNMLGYDVAE
     VREAVERQIA KGVVHTSALY LIRSQVELAE KIARLSGIPD AKVFFTNSGT EANETALLLA
     THARGSDEVL AMRGSYHGRS FGTVAVTGNR AWKNSALSPL NVHYLHGTDH ASPLFRDLSE
     REYIDRCVAD LRAVLDTTAP NVACLIAEPI QGVGGFAMPP EGLYGAYKEV LDEHGILFVS
     DEVQTGWGRT GTDFFGIGAH GVTPDAMTFA KGLGNGFAVG GVVARGDLMD GLGALGVATF
     GGNPVSMAAA GATLDYVLDH DLQDNALRQG RTILEGLRAL RELPCVLDVR GKGLMFAVEM
     VDFESGAPSP ALAAGVLEAT RERGLLVGKG GVHGNVLRMA PPLTLSTEEA AEGRDILNPA
     SGQITGTVDL AGPAEVDAAV AAARAAFPAW RDTPLSKRVR TLFRFRELLD SRSDRLAEIV
     SAEHGKVLSD AKGEVARGLE VVDFACGVPQ LLKGDFSENV STGVDSYSIR QPVGVVAGIT
     PFNFPAMVPM WMFPLAIACG NTFVLKPSEK DPSASLMIAE LWAEAGLPDG VFNVVQGDKV
     AVDALLEHPD VAAVGFVGST PIARYVYRVA AEHGKRVQAL GGAKNHMVVL PDADLDLAAD
     AAVSAGFGSA GERCMAISAV AVVDSVADDL MERIRERVAR LRVGPGDDDR SEMGPLVTRE
     HRDKVASYLE SGVREGATLA IDGRVHPVLG GGGDGFWLGP SVLDHVEPTM SCYREEIFGP
     VLSVLRVRDY DEAVGLINAN PYGNGTAIFT NDGGAARRFQ NEIEVGMVGI NVPIPVPMAY
     YSFGGWKESL FGDSHVHGTE GQRPEGGVDL GFPTNG
//
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