GenomeNet

Database: UniProt/TrEMBL
Entry: J9KB04_ACYPI
LinkDB: J9KB04_ACYPI
Original site: J9KB04_ACYPI 
ID   J9KB04_ACYPI            Unreviewed;       485 AA.
AC   J9KB04;
DT   31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   31-OCT-2012, sequence version 1.
DT   07-JUN-2017, entry version 37.
DE   RecName: Full=Phosphotransferase {ECO:0000256|RuleBase:RU362007};
DE            EC=2.7.1.- {ECO:0000256|RuleBase:RU362007};
GN   Name=LOC100165014 {ECO:0000313|EnsemblMetazoa:ACYPI010135-PA};
OS   Acyrthosiphon pisum (Pea aphid).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Paraneoptera; Hemiptera; Sternorrhyncha;
OC   Aphidomorpha; Aphidoidea; Aphididae; Macrosiphini; Acyrthosiphon.
OX   NCBI_TaxID=7029 {ECO:0000313|EnsemblMetazoa:ACYPI010135-PA, ECO:0000313|Proteomes:UP000007819};
RN   [1] {ECO:0000313|EnsemblMetazoa:ACYPI010135-PA}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LSR1 {ECO:0000313|EnsemblMetazoa:ACYPI010135-PA};
RA   Jiang H., Abraham K., Ali S., Alsbrooks S.L., Anim B.N., Anosike U.S.,
RA   Attaway T., Bandaranaike D.P., Battles P.K., Bell S.N., Bell A.V.,
RA   Beltran B., Bickham C., Bustamante Y., Caleb T., Canada A.,
RA   Cardenas V., Carter K., Chacko J., Chandrabose M.N., Chavez D.,
RA   Chavez A., Chen L., Chu H.-S., Claassen K.J., Cockrell R., Collins M.,
RA   Cooper J.A., Cree A., Curry S.M., Da Y., Dao M.D., Das B.,
RA   Davila M.-L., Davy-Carroll L., Denson S., Dinh H., Ebong V.E.,
RA   Edwards J.R., Egan A., El-Daye J., Escobedo L., Fernandez S.,
RA   Fernando P.R., Flagg N., Forbes L.D., Fowler R.G., Fu Q., Gabisi R.A.,
RA   Ganer J., Garbino Pronczuk A., Garcia R.M., Garner T., Garrett T.E.,
RA   Gonzalez D.A., Hamid H., Hawkins E.S., Hirani K., Hogues M.E.,
RA   Hollins B., Hsiao C.-H., Jabil R., James M.L., Jhangiani S.N.,
RA   Johnson B., Johnson Q., Joshi V., Kalu J.B., Kam C., Kashfia A.,
RA   Keebler J., Kisamo H., Kovar C.L., Lago L.A., Lai C.-Y., Laidlaw J.,
RA   Lara F., Le T.-K., Lee S.L., Legall F.H., Lemon S.J., Lewis L.R.,
RA   Li B., Liu Y., Liu Y.-S., Lopez J., Lozado R.J., Lu J., Madu R.C.,
RA   Maheshwari M., Maheshwari R., Malloy K., Martinez E., Mathew T.,
RA   Mercado I.C., Mercado C., Meyer B., Montgomery K., Morgan M.B.,
RA   Munidasa M., Nazareth L.V., Nelson J., Ng B.M., Nguyen N.B.,
RA   Nguyen P.Q., Nguyen T., Obregon M., Okwuonu G.O., Onwere C.G.,
RA   Orozco G., Parra A., Patel S., Patil S., Perez A., Perez Y., Pham C.,
RA   Primus E.L., Pu L.-L., Puazo M., Qin X., Quiroz J.B., Reese J.,
RA   Richards S., Rives C.M., Robberts R., Ruiz S.J., Ruiz M.J.,
RA   Santibanez J., Schneider B.W., Sisson I., Smith M., Sodergren E.,
RA   Song X.-Z., Song B.B., Summersgill H., Thelus R., Thornton R.D.,
RA   Trejos Z.Y., Usmani K., Vattathil S., Villasana D., Walker D.L.,
RA   Wang S., Wang K., White C.S., Williams A.C., Williamson J., Wilson K.,
RA   Woghiren I.O., Woodworth J.R., Worley K.C., Wright R.A., Wu W.,
RA   Young L., Zhang L., Zhang J., Zhu Y., Muzny D.M., Weinstock G.,
RA   Gibbs R.A.;
RL   Submitted (JUN-2010) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:ACYPI010135-PA}
RP   IDENTIFICATION.
RG   EnsemblMetazoa;
RL   Submitted (JUN-2015) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the hexokinase family.
CC       {ECO:0000256|RuleBase:RU362007, ECO:0000256|SAAS:SAAS00672880}.
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DR   EMBL; ABLF02024587; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_001949411.1; XM_001949376.4.
DR   UniGene; Aps.1905; -.
DR   UniGene; Aps.48219; -.
DR   UniGene; Aps.52277; -.
DR   STRING; 7029.ACYPI010135-PA; -.
DR   EnsemblMetazoa; ACYPI010135-RA; ACYPI010135-PA; ACYPI010135.
DR   GeneID; 100169524; -.
DR   KEGG; api:100169524; -.
DR   eggNOG; KOG1369; Eukaryota.
DR   eggNOG; COG5026; LUCA.
DR   InParanoid; J9KB04; -.
DR   KO; K00844; -.
DR   OMA; ERQFFRA; -.
DR   PhylomeDB; J9KB04; -.
DR   Proteomes; UP000007819; Unassembled WGS sequence.
DR   GO; GO:0005623; C:cell; IEA:GOC.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0005536; F:glucose binding; IEA:InterPro.
DR   GO; GO:0004396; F:hexokinase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0001678; P:cellular glucose homeostasis; IEA:InterPro.
DR   GO; GO:0006096; P:glycolytic process; IEA:UniProtKB-KW.
DR   InterPro; IPR001312; Hexokinase.
DR   InterPro; IPR019807; Hexokinase_BS.
DR   InterPro; IPR022673; Hexokinase_C.
DR   InterPro; IPR022672; Hexokinase_N.
DR   PANTHER; PTHR19443; PTHR19443; 1.
DR   Pfam; PF00349; Hexokinase_1; 1.
DR   Pfam; PF03727; Hexokinase_2; 1.
DR   PROSITE; PS00378; HEXOKINASE_1; 1.
DR   PROSITE; PS51748; HEXOKINASE_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|RuleBase:RU362007,
KW   ECO:0000256|SAAS:SAAS00672869};
KW   Complete proteome {ECO:0000313|Proteomes:UP000007819};
KW   Glycolysis {ECO:0000256|RuleBase:RU362007,
KW   ECO:0000256|SAAS:SAAS00672870};
KW   Kinase {ECO:0000256|RuleBase:RU362007, ECO:0000256|SAAS:SAAS00672871};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU362007,
KW   ECO:0000256|SAAS:SAAS00672883};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007819};
KW   Transferase {ECO:0000256|RuleBase:RU362007,
KW   ECO:0000256|SAAS:SAAS00672884}.
FT   DOMAIN       35    231       Hexokinase_1. {ECO:0000259|Pfam:PF00349}.
FT   DOMAIN      237    469       Hexokinase_2. {ECO:0000259|Pfam:PF03727}.
SQ   SEQUENCE   485 AA;  53854 MW;  0026A9A6C4B08364 CRC64;
     MRTKPEMMGQ LRPAFSELNI SEGFEFDTEL VTNEIKEDCK SLLLSNEQLT TLMKDMDGAI
     RNGLGKDTNP SSIVKCYVTY VQDLPNGTER GKFLALDLGG TNFRVLLIEL GENNYFHMDS
     EIFKVPAHIQ TGKGSELFDH IAKCLAEFIK KHNLDNKKAL PLGFTFSFPL RQVGLTKGYL
     NSWTKGFNCS GVVDEDVVRL LKEAIKRRKD VEIDVCGILN DTTGTIMSCA WKNPNTKIGV
     IVGTGCNACY VEKVENAELF DGDKTKPHVI VNTEWGAFGD DGKLDAVRTK YDREIDEDSL
     NPGRQRFEKM ISGMYMGEIV RLAIVDLANQ NKLFEGRLSE QMKTKGAFGT SFVSDIEGDK
     ANYKETLKVL SEMGINDPSL VDCANVRYIC ECVSRRSAHL VSAGLAALLN KMDEKSVTIG
     VDGSVYRFHP YFHKLMVEKT KQLTKSDIKF DLMLSEDGSG RGAALVAAVA VRDELPSMTN
     GFSAK
//
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