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Database: UniProt/TrEMBL
Entry: K3VVC9_FUSPC
LinkDB: K3VVC9_FUSPC
Original site: K3VVC9_FUSPC 
ID   K3VVC9_FUSPC            Unreviewed;       984 AA.
AC   K3VVC9;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   07-JUN-2017, entry version 27.
DE   RecName: Full=DNA ligase {ECO:0000256|RuleBase:RU000617};
DE            EC=6.5.1.1 {ECO:0000256|RuleBase:RU000617};
GN   ORFNames=FPSE_00173 {ECO:0000313|EMBL:EKJ79719.1};
OS   Fusarium pseudograminearum (strain CS3096) (Wheat and barley crown-rot
OS   fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
OC   Sordariomycetes; Hypocreomycetidae; Hypocreales; Nectriaceae;
OC   Fusarium.
OX   NCBI_TaxID=1028729 {ECO:0000313|EMBL:EKJ79719.1, ECO:0000313|Proteomes:UP000007978};
RN   [1] {ECO:0000313|EMBL:EKJ79719.1, ECO:0000313|Proteomes:UP000007978}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CS3096 {ECO:0000313|EMBL:EKJ79719.1,
RC   ECO:0000313|Proteomes:UP000007978};
RX   PubMed=23028337; DOI=10.1371/journal.ppat.1002952;
RA   Gardiner D.M., McDonald M.C., Covarelli L., Solomon P.S., Rusu A.G.,
RA   Marshall M., Kazan K., Chakraborty S., McDonald B.A., Manners J.M.;
RT   "Comparative pathogenomics reveals horizontally acquired novel
RT   virulence genes in fungi infecting cereal hosts.";
RL   PLoS Pathog. 8:E1002952-E1002952(2012).
CC   -!- CATALYTIC ACTIVITY: ATP + (deoxyribonucleotide)(n)-3'-hydroxyl +
CC       5'-phospho-(deoxyribonucleotide)(m) = (deoxyribonucleotide)(n+m) +
CC       AMP + diphosphate. {ECO:0000256|RuleBase:RU000617}.
CC   -!- SIMILARITY: Belongs to the ATP-dependent DNA ligase family.
CC       {ECO:0000256|RuleBase:RU004196}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:EKJ79719.1}.
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DR   EMBL; AFNW01000004; EKJ79719.1; -; Genomic_DNA.
DR   RefSeq; XP_009251568.1; XM_009253293.1.
DR   EnsemblFungi; EKJ79719; EKJ79719; FPSE_00173.
DR   GeneID; 20358793; -.
DR   KEGG; fpu:FPSE_00173; -.
DR   InParanoid; K3VVC9; -.
DR   KO; K10777; -.
DR   OrthoDB; EOG092C18KW; -.
DR   Proteomes; UP000007978; Chromosome 2.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003910; F:DNA ligase (ATP) activity; IEA:UniProtKB-EC.
DR   GO; GO:0071897; P:DNA biosynthetic process; IEA:InterPro.
DR   GO; GO:0051103; P:DNA ligation involved in DNA repair; IEA:InterPro.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   CDD; cd00027; BRCT; 2.
DR   Gene3D; 1.10.3260.10; -; 1.
DR   Gene3D; 3.40.50.10190; -; 2.
DR   InterPro; IPR001357; BRCT_dom.
DR   InterPro; IPR000977; DNA_ligase_ATP-dep.
DR   InterPro; IPR012309; DNA_ligase_ATP-dep_C.
DR   InterPro; IPR012310; DNA_ligase_ATP-dep_cent.
DR   InterPro; IPR016059; DNA_ligase_ATP-dep_CS.
DR   InterPro; IPR012308; DNA_ligase_ATP-dep_N.
DR   InterPro; IPR029710; LIG4.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   PANTHER; PTHR10459:SF84; PTHR10459:SF84; 1.
DR   Pfam; PF16589; BRCT_2; 1.
DR   Pfam; PF04679; DNA_ligase_A_C; 1.
DR   Pfam; PF01068; DNA_ligase_A_M; 1.
DR   Pfam; PF04675; DNA_ligase_A_N; 1.
DR   SMART; SM00292; BRCT; 2.
DR   SUPFAM; SSF117018; SSF117018; 1.
DR   SUPFAM; SSF50249; SSF50249; 1.
DR   SUPFAM; SSF52113; SSF52113; 2.
DR   TIGRFAMs; TIGR00574; dnl1; 1.
DR   PROSITE; PS50172; BRCT; 2.
DR   PROSITE; PS00697; DNA_LIGASE_A1; 1.
DR   PROSITE; PS50160; DNA_LIGASE_A3; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|RuleBase:RU000617};
KW   Complete proteome {ECO:0000313|Proteomes:UP000007978};
KW   DNA damage {ECO:0000256|RuleBase:RU000617};
KW   DNA recombination {ECO:0000256|RuleBase:RU000617};
KW   DNA repair {ECO:0000256|RuleBase:RU000617};
KW   DNA replication {ECO:0000256|RuleBase:RU000617};
KW   Ligase {ECO:0000256|RuleBase:RU000617};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU000617}.
FT   DOMAIN      427    552       DNA_LIGASE_A3. {ECO:0000259|PROSITE:
FT                                PS50160}.
FT   DOMAIN      720    802       BRCT. {ECO:0000259|PROSITE:PS50172}.
FT   DOMAIN      882    983       BRCT. {ECO:0000259|PROSITE:PS50172}.
SQ   SEQUENCE   984 AA;  112594 MW;  6D4009DD0DE1FEDF CRC64;
     MSQNDDAQHE DDIQYASMGV TREELEEKYP NRPKNHSKTL VFSELFREVF NPLNENKKQN
     AAGSGPKNSF RGVNKLSPHE QRRHIIDRFI TRWRKEVGFD FYPALRLILP DKDRDRGVYG
     LKENAIGKLL VKLMKIDKNS EDGYNLLHWK LPGQTMASRL AGDFAGRCFE VISKRPMRTQ
     VGNMTIAEVN EQLDKLAASS GEMENLRVFE IFYHRMNSEE LMWLIRIVLK QMKVGATEKT
     FLDLWHPDGD ALFSVSSSLK RVCWELWNPE IRLEQGETGV ALMQCFQPQL AQFQMPASFQ
     KMIQLLRPTE EDPEFWIEEK LDGERMQVHM VQDKSHPGGR KFCFWSRKAK DYTYLYGDGL
     QDETSSLTRH LKDAFTSGVK NLILDGEMIT WDMGVDKIVP FGTLKTAAIS EQQNKSGTDS
     VGHRPLFRVF DILYLNNKPL TQYTLRDRHR ALEKAIKPVH RRLEIHEYTS ATSADAIEPL
     LREVVANASE GLVLKNPRSM YRLNSRNDDW LKVKPEYMSE FGESLDCVII AGYYGTGKRG
     GALSSFLCGL RVTQNHIQAG ANPEKCFSFF KVGGGFRAED YAEIRHRTEG KWIEWDQRNP
     PSEYIELGGG EARQFERPDV WIRPKDSVVV SVKAASVGPS DSFALGFTLR FPRFRRLRLD
     RSWNTALSLE EFQELKQRVD EESKEKAMTV EDRKRHNPKR VKRELTIAGE DTNVAEFIGE
     TTKLFEGLEF CVLSEALRPY KKTKTQLETI IKENGGVISQ RAAPGTNMVL IADKKVVKVA
     SLVKGGDVNI IRPKWIRDCL EQELGAFLLP FEDTHLFHAT DALKRAANEN TDQFGDSYIR
     DLSIEELRQV MNDMPKIEDG IAFDKNEFLQ QLEERGKDLG PLKSLTFRRC VVLFHAVEAG
     DKRMSRLENL VRFGGGSVTD DANDLSVTHV VIQGDDPMQV GEAADMIRKE LSLRPIQPRV
     VTGAWIDECW KESTLLDEEQ FAVP
//
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