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Database: UniProt/TrEMBL
Entry: K7GLF7_PIG
LinkDB: K7GLF7_PIG
Original site: K7GLF7_PIG 
ID   K7GLF7_PIG              Unreviewed;       826 AA.
AC   K7GLF7;
DT   09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT   09-JAN-2013, sequence version 1.
DT   27-SEP-2017, entry version 33.
DE   SubName: Full=Transglutaminase 1 {ECO:0000313|Ensembl:ENSSSCP00000028686};
GN   Name=TGM1 {ECO:0000313|Ensembl:ENSSSCP00000028686};
OS   Sus scrofa (Pig).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;
OC   Sus.
OX   NCBI_TaxID=9823 {ECO:0000313|Ensembl:ENSSSCP00000028686, ECO:0000313|Proteomes:UP000008227};
RN   [1] {ECO:0000313|Ensembl:ENSSSCP00000028686, ECO:0000313|Proteomes:UP000008227}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Duroc {ECO:0000313|Ensembl:ENSSSCP00000028686};
RG   Porcine genome sequencing project;
RL   Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSSSCP00000028686}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2012) to UniProtKB.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSSSCP00000028686}.
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DR   EMBL; CU019590; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_001927930.2; XM_001927895.4.
DR   PaxDb; K7GLF7; -.
DR   Ensembl; ENSSSCT00000035836; ENSSSCP00000028686; ENSSSCG00000001993.
DR   KEGG; ssc:100156489; -.
DR   CTD; 7051; -.
DR   eggNOG; ENOG410IFMV; Eukaryota.
DR   eggNOG; ENOG410XQEZ; LUCA.
DR   GeneTree; ENSGT00760000119108; -.
DR   KO; K05619; -.
DR   Reactome; R-SSC-6809371; Formation of the cornified envelope.
DR   Proteomes; UP000008227; Chromosome 7.
DR   Bgee; ENSSSCG00000001993; -.
DR   ExpressionAtlas; K7GLF7; differential.
DR   Genevisible; K7GLF7; SS.
DR   GO; GO:0070062; C:extracellular exosome; IEA:Ensembl.
DR   GO; GO:0031224; C:intrinsic component of membrane; IEA:Ensembl.
DR   GO; GO:0003810; F:protein-glutamine gamma-glutamyltransferase activity; IEA:Ensembl.
DR   GO; GO:0030216; P:keratinocyte differentiation; IEA:Ensembl.
DR   GO; GO:0018149; P:peptide cross-linking; IEA:Ensembl.
DR   GO; GO:0045787; P:positive regulation of cell cycle; IEA:Ensembl.
DR   GO; GO:0010838; P:positive regulation of keratinocyte proliferation; IEA:Ensembl.
DR   Gene3D; 2.60.40.10; -; 3.
DR   Gene3D; 3.90.260.10; -; 1.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR002931; Transglutaminase-like.
DR   InterPro; IPR023608; Transglutaminase_animal.
DR   InterPro; IPR013808; Transglutaminase_AS.
DR   InterPro; IPR008958; Transglutaminase_C.
DR   InterPro; IPR001102; Transglutaminase_N.
DR   Pfam; PF00927; Transglut_C; 2.
DR   Pfam; PF01841; Transglut_core; 1.
DR   Pfam; PF00868; Transglut_N; 1.
DR   PIRSF; PIRSF000459; TGM_EBP42; 1.
DR   SMART; SM00460; TGc; 1.
DR   SUPFAM; SSF49309; SSF49309; 2.
DR   SUPFAM; SSF81296; SSF81296; 1.
DR   PROSITE; PS00547; TRANSGLUTAMINASES; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000008227};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008227}.
FT   DOMAIN      379    472       TGc. {ECO:0000259|SMART:SM00460}.
FT   ACT_SITE    387    387       {ECO:0000256|PIRSR:PIRSR000459-1}.
FT   ACT_SITE    446    446       {ECO:0000256|PIRSR:PIRSR000459-1}.
FT   ACT_SITE    469    469       {ECO:0000256|PIRSR:PIRSR000459-1}.
SQ   SEQUENCE   826 AA;  90879 MW;  57A0A33DE1F8DE4D CRC64;
     MPSPTPPSGT TDGARSDVGR WGGNPWQPPT TPSPEPEPEP DRRSRRDGRS FWARCCGCCS
     CRNTDDDWGP RGDRGAGSRD RGSGSGSRRP DSRGSDSRRP GSRGSGVNAA GDGTIREGML
     VVKGVDLLSS RSDQNRREHH TDEFEYDELI IRRGQPFYMV LLLSRPYESS DYVALELLIG
     NNPEVGKGTH IIIPVGKGGS GGWKAQVTKS SGQNLNLRVH TSPNAIIGKF QFTVRTRSEA
     GEFQLPFNPR NEIYILFNPW CPEDIVYVDH EDWRQEYVLN ESGRIYYGTE AQIGERTWNY
     GQFDHGVLDA CLYILDRRGM PYAGRGDPVS VSRVISAMVN SLDDNGVLIG NWSGDYSRGT
     NPSAWVGSVE ILLSYLRTGY SVPYGQCWVF AGVTTTVLRC LGLATRTVTN FNSAHDTDTS
     LTMDIYFDEN MKPLEHLNHD SVWNFHVWND CWMKRPDLPS GFNGWQVVDA TPQETSSGIF
     CCGPCSVESI KNGLVYMKYD TPFIFAEVNS DKVYWQRQND GSFKIVYVEE KAIGTLIVTK
     AIGSHMREDV THIYKHPEGS EAERKAVETA AAHGSKPNVY ATRDSAEDVA VQVEAQDAVM
     GQDLTVCVVL TNRGGSRRTV KLHLYLSVTF YTGVTGSVFK ESKKEVVLEP GASERVTMPV
     AYKEYQPHLV DQGAMLLNVS GHVKENGQVL AKQHTFRLRT PDLSLTLLGA AVVGQECEVQ
     IVFKNPLPVT LTNVVFRLEG SGLQRPKILN VGDIGGNETV TLRQTFVPVR PGPRQLIASL
     DSPQLSQVHG VIQVDVAPAA GGGVFSDARG NSRSGETIPM ASRGEA
//
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