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Database: UniProt/TrEMBL
Entry: L0HDG7_METFS
LinkDB: L0HDG7_METFS
Original site: L0HDG7_METFS 
ID   L0HDG7_METFS            Unreviewed;       478 AA.
AC   L0HDG7;
DT   06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2013, sequence version 1.
DT   27-SEP-2017, entry version 18.
DE   RecName: Full=Phosphoenolpyruvate carboxylase {ECO:0000256|HAMAP-Rule:MF_01904};
DE            Short=PEPC {ECO:0000256|HAMAP-Rule:MF_01904};
DE            Short=PEPCase {ECO:0000256|HAMAP-Rule:MF_01904};
DE            EC=4.1.1.31 {ECO:0000256|HAMAP-Rule:MF_01904};
GN   Name=ppcA {ECO:0000256|HAMAP-Rule:MF_01904};
GN   OrderedLocusNames=Metfor_1008 {ECO:0000313|EMBL:AGB02060.1};
OS   Methanoregula formicica (strain DSM 22288 / NBRC 105244 / SMSP).
OC   Archaea; Euryarchaeota; Methanomicrobia; Methanomicrobiales;
OC   Methanoregulaceae; Methanoregula.
OX   NCBI_TaxID=593750 {ECO:0000313|EMBL:AGB02060.1, ECO:0000313|Proteomes:UP000010824};
RN   [1] {ECO:0000313|Proteomes:UP000010824}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 22288 / NBRC 105244 / SMSP
RC   {ECO:0000313|Proteomes:UP000010824};
RA   Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA   Peters L., Ovchinnikova G., Teshima H., Detter J.C., Han C., Tapia R.,
RA   Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Imachi H.,
RA   Tamaki H., Sekiguchi Y., Kamagata Y., Cadillo-Quiroz H., Zinder S.,
RA   Liu W.-T., Woyke T.;
RT   "Complete sequence of Methanoregula formicicum SMSP.";
RL   Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Catalyzes the irreversible beta-carboxylation of
CC       phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-
CC       carbon dicarboxylic acid source for the tricarboxylic acid cycle.
CC       {ECO:0000256|HAMAP-Rule:MF_01904}.
CC   -!- CATALYTIC ACTIVITY: Phosphate + oxaloacetate = H(2)O +
CC       phosphoenolpyruvate + HCO(3)(-). {ECO:0000256|HAMAP-
CC       Rule:MF_01904}.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000256|HAMAP-
CC         Rule:MF_01904};
CC   -!- SUBUNIT: Homotetramer. {ECO:0000256|HAMAP-Rule:MF_01904}.
CC   -!- SIMILARITY: Belongs to the PEPCase type 2 family.
CC       {ECO:0000256|HAMAP-Rule:MF_01904}.
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DR   EMBL; CP003167; AGB02060.1; -; Genomic_DNA.
DR   EnsemblBacteria; AGB02060; AGB02060; Metfor_1008.
DR   KEGG; mfo:Metfor_1008; -.
DR   KO; K01595; -.
DR   OMA; PAMNYGL; -.
DR   OrthoDB; POG093Z01LI; -.
DR   Proteomes; UP000010824; Chromosome.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0008964; F:phosphoenolpyruvate carboxylase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0015977; P:carbon fixation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006107; P:oxaloacetate metabolic process; IEA:UniProtKB-UniRule.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR   HAMAP; MF_01904; PEPcase_type2; 1.
DR   InterPro; IPR007566; PEP_COase_arc-type.
DR   InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR   Pfam; PF14010; PEPcase_2; 1.
DR   PIRSF; PIRSF006677; UCP006677; 1.
DR   SUPFAM; SSF51621; SSF51621; 1.
DR   TIGRFAMs; TIGR02751; PEPCase_arch; 1.
PE   3: Inferred from homology;
KW   Carbon dioxide fixation {ECO:0000256|HAMAP-Rule:MF_01904};
KW   Complete proteome {ECO:0000313|Proteomes:UP000010824};
KW   Lyase {ECO:0000256|HAMAP-Rule:MF_01904};
KW   Magnesium {ECO:0000256|HAMAP-Rule:MF_01904};
KW   Pyruvate {ECO:0000313|EMBL:AGB02060.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000010824}.
SQ   SEQUENCE   478 AA;  54217 MW;  C286F8F731AEB71F CRC64;
     MSTQHPDNVH VPFFAETSEL GGEDEVKEAY YIYSHLGCHE QMWDCEGKEV DNFVVKKLLT
     TYSPFFADNI LGKDIFLTLR VPNPHIEKAE AKILLETLES IPRSFDVARI FYKNDIPPIF
     EVILPMTDTH TAIDNIYQYY ADFVIGKQFK RLGGRDTTIA DWIGTFSPKH INVIPLFEDQ
     TSMLSAHTTV GRYILDKHLP YQRVFLARSD PAMNYGLVSA VLLNKIALAN LHRLQEETGV
     PVYPVIGVGS APFRGNLRPD TVDRVSAEYP SAYTFTIQSA FKYDYPPDEA RNAVRALESR
     AVSTPHRVDE TQCLQIMERY TEAYIRELIP LSDIINRIAG HIPGRRKRKL HIGLFGYSRN
     TGGMKLPRAI TFTAALYSIG IPPEILGLSA LSDRDLDFVR RIYVNFDRDL CDAARYLNPD
     SPYLGEGMKD ALLSITGDRI NDDHRQATEN ILRALRESRT AEIQSDILHA ANIRKFLG
//
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