ID L0IJE3_THETR Unreviewed; 906 AA.
AC L0IJE3;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=Transcriptional antiterminator {ECO:0000313|EMBL:AGB18336.1};
GN ORFNames=Thethe_00646 {ECO:0000313|EMBL:AGB18336.1};
OS Thermoanaerobacterium thermosaccharolyticum M0795.
OC Bacteria; Bacillota; Clostridia; Thermoanaerobacterales;
OC Thermoanaerobacteraceae; Thermoanaerobacterium.
OX NCBI_TaxID=698948 {ECO:0000313|EMBL:AGB18336.1, ECO:0000313|Proteomes:UP000010845};
RN [1] {ECO:0000313|EMBL:AGB18336.1, ECO:0000313|Proteomes:UP000010845}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M0795 {ECO:0000313|EMBL:AGB18336.1,
RC ECO:0000313|Proteomes:UP000010845};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Teshima H., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA Kyrpides N., Ivanova N., Pagani I., Feinberg L., Folden J., Hogsett D.,
RA Shaw J., Woyke T.;
RT "Complete sequence of chromosome of Thermoanaerobacterium
RT thermosaccharolyticum M0795.";
RL Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP003066; AGB18336.1; -; Genomic_DNA.
DR AlphaFoldDB; L0IJE3; -.
DR KEGG; tto:Thethe_00646; -.
DR PATRIC; fig|698948.3.peg.626; -.
DR HOGENOM; CLU_014204_1_0_9; -.
DR Proteomes; UP000010845; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.510; Phosphotransferase system, mannose-type IIA component; 1.
DR Gene3D; 1.10.1790.10; PRD domain; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011608; PRD.
DR InterPro; IPR036634; PRD_sf.
DR InterPro; IPR004701; PTS_EIIA_man-typ.
DR InterPro; IPR036662; PTS_EIIA_man-typ_sf.
DR InterPro; IPR002078; Sigma_54_int.
DR InterPro; IPR025943; Sigma_54_int_dom_ATP-bd_2.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR32071:SF38; PSP OPERON TRANSCRIPTIONAL ACTIVATOR; 1.
DR PANTHER; PTHR32071; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF03610; EIIA-man; 1.
DR Pfam; PF00874; PRD; 2.
DR Pfam; PF00158; Sigma54_activat; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF53062; PTS system fructose IIA component-like; 1.
DR SUPFAM; SSF63520; PTS-regulatory domain, PRD; 2.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51372; PRD_2; 2.
DR PROSITE; PS51096; PTS_EIIA_TYPE_4; 1.
DR PROSITE; PS00676; SIGMA54_INTERACT_2; 1.
DR PROSITE; PS50045; SIGMA54_INTERACT_4; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 88..321
FT /note="Sigma-54 factor interaction"
FT /evidence="ECO:0000259|PROSITE:PS50045"
FT DOMAIN 443..548
FT /note="PRD"
FT /evidence="ECO:0000259|PROSITE:PS51372"
FT DOMAIN 551..691
FT /note="PTS EIIA type-4"
FT /evidence="ECO:0000259|PROSITE:PS51096"
FT DOMAIN 800..906
FT /note="PRD"
FT /evidence="ECO:0000259|PROSITE:PS51372"
SQ SEQUENCE 906 AA; 102963 MW; 3F84D85A692FFBBE CRC64;
MVKGIFKLKR KELILKKLIE LNRGNGVDAM TLANELNMSR ANVSHELNLL CKEGKVVKSD
GRPVMFSPVF ENTKSNSSDS KLYELDMLIK NNISLKQAGE QAKAAILYPP KGIHCLILGE
TGVGKSTFAR IMHKYAIDMG VKKPDAPFIA FNCADYSNNP QLLTAQLFGV KKGAYTGADT
DKEGLIEKAN GGILFLDEVH RLPPEGQEIL FTFLDTGYFR RVGDVENRTS DVLIISATTE
DPSSSLLNTF TRRIPMIIKI PPLRERTLEE RFYLLKRFFK HESIKLNRDI FVSLNSMRAF
CSYDCPNNIG QLESDVKLIC AKVYSEFLTN KKSDIRICSR DLPDYIKKGL YTDKQHRMLW
NEVIGDDIEF FKFSPTNEIE EIPTASNDNS IYEIINDRLR QLKAKGISDI DIESILEKDI
AKYFHKQIYG ITEEKNKQNL IHILGEDIIS ITDRIAELVS ELLGKELSQN SYTALALHLN
TLIERVNKNK PIVNPQLSKI KQLYPREFEV AIEAKKIIER YLNVSIPEDE AGFIAIFLMS
DKEYINKQSE KVKVIIIAHG NSTATSMADV ANKLLGENYA IGLDAHLDKS PLEVLETLKD
YVRNDMNQAG YLLLVDMGSL TTFGETIERE FNVPVKVIPL ISTLHVIEAT RKALLGMPLN
NIYMSVQSIN SYMENNMDFA PPISDKKKIA IITACLTGEG ASVAIKSFLK NNLKYDKDLF
EIIPIDSLDK HMTMKKINEI QENMEIAFIV SSFPLDTNIK QYSMNDVLSL KVMKELQEIV
DIKTTLIKMG NVLKENIHNI DGEELYIDIQ NTIMKLCDTL SICFDDDMLL GIILHFAFMV
SRIKKGEKSI EYIGKEEYIK SNKSLYNAVK KALTHLNTKY SIIIPDDEIC YIMRFFQEKD
ALFNMI
//
