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Database: UniProt/TrEMBL
Entry: L8GWF8_ACACA
LinkDB: L8GWF8_ACACA
Original site: L8GWF8_ACACA 
ID   L8GWF8_ACACA            Unreviewed;       916 AA.
AC   L8GWF8;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   07-JUN-2017, entry version 15.
DE   SubName: Full=Phosphoenolpyruvate carboxylase {ECO:0000313|EMBL:ELR17267.1};
GN   ORFNames=ACA1_059840 {ECO:0000313|EMBL:ELR17267.1};
OS   Acanthamoeba castellanii str. Neff.
OC   Eukaryota; Amoebozoa; Discosea; Longamoebia; Centramoebida;
OC   Acanthamoebidae; Acanthamoeba.
OX   NCBI_TaxID=1257118 {ECO:0000313|EMBL:ELR17267.1, ECO:0000313|Proteomes:UP000011083};
RN   [1] {ECO:0000313|EMBL:ELR17267.1, ECO:0000313|Proteomes:UP000011083}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Neff {ECO:0000313|EMBL:ELR17267.1,
RC   ECO:0000313|Proteomes:UP000011083};
RX   PubMed=23375108; DOI=10.1186/gb-2013-14-2-r11;
RA   Clarke M., Lohan A.J., Liu B., Lagkouvardos I., Roy S., Zafar N.,
RA   Bertelli C., Schilde C., Kianianmomeni A., Burglin T.R., Frech C.,
RA   Turcotte B., Kopec K.O., Synnott J.M., Choo C., Paponov I.,
RA   Finkler A., Soon Heng Tan C., Hutchins A.P., Weinmeier T., Rattei T.,
RA   Chu J.S., Gimenez G., Irimia M., Rigden D.J., Fitzpatrick D.A.,
RA   Lorenzo-Morales J., Bateman A., Chiu C.H., Tang P., Hegemann P.,
RA   Fromm H., Raoult D., Greub G., Miranda-Saavedra D., Chen N., Nash P.,
RA   Ginger M.L., Horn M., Schaap P., Caler L., Loftus B.;
RT   "Genome of Acanthamoeba castellanii highlights extensive lateral gene
RT   transfer and early evolution of tyrosine kinase signaling.";
RL   Genome Biol. 14:R11-R11(2013).
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DR   EMBL; KB007974; ELR17267.1; -; Genomic_DNA.
DR   RefSeq; XP_004339280.1; XM_004339232.1.
DR   EnsemblProtists; ELR17267; ELR17267; ACA1_059840.
DR   GeneID; 14917863; -.
DR   KEGG; acan:ACA1_059840; -.
DR   EuPathDB; AmoebaDB:ACA1_059840; -.
DR   KO; K01595; -.
DR   Proteomes; UP000011083; Unassembled WGS sequence.
DR   GO; GO:0008964; F:phosphoenolpyruvate carboxylase activity; IEA:InterPro.
DR   GO; GO:0015977; P:carbon fixation; IEA:InterPro.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR   HAMAP; MF_00595; PEPcase_type1; 1.
DR   InterPro; IPR021135; PEP_COase.
DR   InterPro; IPR022805; PEP_COase_bac/pln-type.
DR   InterPro; IPR018129; PEP_COase_Lys_AS.
DR   InterPro; IPR033129; PEPCASE_His_AS.
DR   InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR   Pfam; PF00311; PEPcase; 1.
DR   PRINTS; PR00150; PEPCARBXLASE.
DR   SUPFAM; SSF51621; SSF51621; 1.
DR   PROSITE; PS00781; PEPCASE_1; 1.
DR   PROSITE; PS00393; PEPCASE_2; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000011083};
KW   Pyruvate {ECO:0000313|EMBL:ELR17267.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000011083}.
FT   ACT_SITE    160    160       {ECO:0000256|PROSITE-ProRule:PRU10111}.
FT   ACT_SITE    581    581       {ECO:0000256|PROSITE-ProRule:PRU10112}.
SQ   SEQUENCE   916 AA;  103464 MW;  3BA3A78EAB6F26BA CRC64;
     MGDAIVNLGV PANPSAVPHA HTAFDDDLDL LDDLLHKTIK SMDEDGEKLN QLVKDVVGMA
     KEWRSDPAHH SHTSFDDFIK SMKSKDALRL VRIISHYLNL ANVADQHHIV RLMRKHQIEQ
     TPLPYTFQQV FDTLIEAGVS TDDIYQALME QKIEPVLTAH PTQVMRRTIL SKNNKISEAL
     ARRDFQQLTT EEKEEVFAAL RREIGGAWLS DEIRRKRPTP DEEAMGGLAV IEQSLSLADS
     DRSTGHAVPK LLRRLDWTVQ KYTGKSLPPE FSNLTFGSWM GGDRDGNPNV TPEVTKRCCY
     FSRWIAADLY YREVDALLFE LSMIRCTKEL TEEAALAAER RRRHGEKYLT TLYKEFREGI
     PEKEAYRIVL AEVRDTFLVT KRRLEDMIMG KPISSESTYY TQTSEVLAPL CLCYRSLKET
     GAGEIADGRL LDLIRRLSSF GLGLVKLDIR QESDRHTEVL DTITTYLGMG SYEEWDEEKR
     VEFLRVKEVL ETFKVAASLG PESLGAYVIS MCRTASDILA VELLQKEAGN KHPQRVVPLF
     ETVDDLRNSA PVMRRLFSND WYRTHIKGRQ EIMIGYSDSA KDAGRLTSAW ELYKAQEALL
     KLCEEFGVKL TLFHGRGGTV GRGGGPSYLA IQSQPPGTLA GRLRVTEQGE MIQSQFGLPG
     IAYRTLEVYV TATLKTRFLP PVRPTPRWCE IMDRLSATAC DAYRALIRGN PRFVEYFRAA
     TPSGELSYLN IGSRPAKRNV QGGIESLRAI PWIFAWTQTR LLLPAWLGVG EALELAAQEG
     LGEELKTMYA EWPFFQSTVD LVEMVLSKGD PEIAARYNEV LVPPELQEMG HQLVQKFNFT
     ATHILSLTGH KVLQESNPLL LESINLRRGF VDPINLIQVE ILRRMREGKD GQVDEVLLDA
     FIITINGIAA GMRNTG
//
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