GenomeNet

Database: UniProt/TrEMBL
Entry: M2RZI9_COCSN
LinkDB: M2RZI9_COCSN
Original site: M2RZI9_COCSN 
ID   M2RZI9_COCSN            Unreviewed;       994 AA.
AC   M2RZI9;
DT   01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2013, sequence version 1.
DT   07-JUN-2017, entry version 23.
DE   RecName: Full=DNA ligase {ECO:0000256|RuleBase:RU000617};
DE            EC=6.5.1.1 {ECO:0000256|RuleBase:RU000617};
GN   ORFNames=COCSADRAFT_243297 {ECO:0000313|EMBL:EMD60473.1};
OS   Cochliobolus sativus (strain ND90Pr / ATCC 201652) (Common root rot
OS   and spot blotch fungus) (Bipolaris sorokiniana).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
OC   Dothideomycetes; Pleosporomycetidae; Pleosporales; Pleosporineae;
OC   Pleosporaceae; Bipolaris.
OX   NCBI_TaxID=665912 {ECO:0000313|EMBL:EMD60473.1, ECO:0000313|Proteomes:UP000016934};
RN   [1] {ECO:0000313|EMBL:EMD60473.1, ECO:0000313|Proteomes:UP000016934}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ND90Pr / ATCC 201652 {ECO:0000313|Proteomes:UP000016934};
RX   PubMed=23236275; DOI=10.1371/journal.ppat.1003037;
RA   Ohm R.A., Feau N., Henrissat B., Schoch C.L., Horwitz B.A.,
RA   Barry K.W., Condon B.J., Copeland A.C., Dhillon B., Glaser F.,
RA   Hesse C.N., Kosti I., LaButti K., Lindquist E.A., Lucas S.,
RA   Salamov A.A., Bradshaw R.E., Ciuffetti L., Hamelin R.C., Kema G.H.J.,
RA   Lawrence C., Scott J.A., Spatafora J.W., Turgeon B.G.,
RA   de Wit P.J.G.M., Zhong S., Goodwin S.B., Grigoriev I.V.;
RT   "Diverse lifestyles and strategies of plant pathogenesis encoded in
RT   the genomes of eighteen Dothideomycetes fungi.";
RL   PLoS Pathog. 8:E1003037-E1003037(2012).
RN   [2] {ECO:0000313|Proteomes:UP000016934}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ND90Pr / ATCC 201652 {ECO:0000313|Proteomes:UP000016934};
RX   PubMed=23357949; DOI=10.1371/journal.pgen.1003233;
RA   Condon B.J., Leng Y., Wu D., Bushley K.E., Ohm R.A., Otillar R.,
RA   Martin J., Schackwitz W., Grimwood J., MohdZainudin N., Xue C.,
RA   Wang R., Manning V.A., Dhillon B., Tu Z.J., Steffenson B.J.,
RA   Salamov A., Sun H., Lowry S., LaButti K., Han J., Copeland A.,
RA   Lindquist E., Barry K., Schmutz J., Baker S.E., Ciuffetti L.M.,
RA   Grigoriev I.V., Zhong S., Turgeon B.G.;
RT   "Comparative genome structure, secondary metabolite, and effector
RT   coding capacity across Cochliobolus pathogens.";
RL   PLoS Genet. 9:E1003233-E1003233(2013).
CC   -!- CATALYTIC ACTIVITY: ATP + (deoxyribonucleotide)(n)-3'-hydroxyl +
CC       5'-phospho-(deoxyribonucleotide)(m) = (deoxyribonucleotide)(n+m) +
CC       AMP + diphosphate. {ECO:0000256|RuleBase:RU000617}.
CC   -!- SIMILARITY: Belongs to the ATP-dependent DNA ligase family.
CC       {ECO:0000256|RuleBase:RU004196}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; KB445650; EMD60473.1; -; Genomic_DNA.
DR   RefSeq; XP_007703812.1; XM_007705622.1.
DR   EnsemblFungi; EMD60473; EMD60473; COCSADRAFT_243297.
DR   GeneID; 19135050; -.
DR   KEGG; bsc:COCSADRAFT_243297; -.
DR   KO; K10777; -.
DR   OrthoDB; EOG092C18KW; -.
DR   Proteomes; UP000016934; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003910; F:DNA ligase (ATP) activity; IEA:UniProtKB-EC.
DR   GO; GO:0071897; P:DNA biosynthetic process; IEA:InterPro.
DR   GO; GO:0051103; P:DNA ligation involved in DNA repair; IEA:InterPro.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   CDD; cd00027; BRCT; 1.
DR   Gene3D; 1.10.3260.10; -; 1.
DR   Gene3D; 3.40.50.10190; -; 2.
DR   InterPro; IPR001357; BRCT_dom.
DR   InterPro; IPR000977; DNA_ligase_ATP-dep.
DR   InterPro; IPR012309; DNA_ligase_ATP-dep_C.
DR   InterPro; IPR012310; DNA_ligase_ATP-dep_cent.
DR   InterPro; IPR016059; DNA_ligase_ATP-dep_CS.
DR   InterPro; IPR012308; DNA_ligase_ATP-dep_N.
DR   InterPro; IPR029710; LIG4.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   PANTHER; PTHR10459:SF84; PTHR10459:SF84; 1.
DR   Pfam; PF16589; BRCT_2; 1.
DR   Pfam; PF04679; DNA_ligase_A_C; 1.
DR   Pfam; PF01068; DNA_ligase_A_M; 1.
DR   Pfam; PF04675; DNA_ligase_A_N; 1.
DR   SUPFAM; SSF117018; SSF117018; 1.
DR   SUPFAM; SSF50249; SSF50249; 1.
DR   SUPFAM; SSF52113; SSF52113; 2.
DR   TIGRFAMs; TIGR00574; dnl1; 1.
DR   PROSITE; PS50172; BRCT; 2.
DR   PROSITE; PS00697; DNA_LIGASE_A1; 1.
DR   PROSITE; PS50160; DNA_LIGASE_A3; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|RuleBase:RU000617};
KW   Complete proteome {ECO:0000313|Proteomes:UP000016934};
KW   DNA damage {ECO:0000256|RuleBase:RU000617};
KW   DNA recombination {ECO:0000256|RuleBase:RU000617};
KW   DNA repair {ECO:0000256|RuleBase:RU000617};
KW   DNA replication {ECO:0000256|RuleBase:RU000617};
KW   Ligase {ECO:0000256|RuleBase:RU000617};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU000617};
KW   Reference proteome {ECO:0000313|Proteomes:UP000016934}.
FT   DOMAIN      432    557       DNA_LIGASE_A3. {ECO:0000259|PROSITE:
FT                                PS50160}.
FT   DOMAIN      727    811       BRCT. {ECO:0000259|PROSITE:PS50172}.
FT   DOMAIN      896    993       BRCT. {ECO:0000259|PROSITE:PS50172}.
SQ   SEQUENCE   994 AA;  114637 MW;  3757E3007A18E5A7 CRC64;
     MAEDTPMLDA DAVRENTLMY GHDDDLDEKY PMRPLNLHKT LPFHTLFTDL FNPLMDTQKK
     KQPVGPRRKV GPHGRGSLTP HEAKRNIVER FIANWRKQVG NDFYPAMRLI IPEKDRDRAM
     YGLKEKAIAK VLIKLTRIGK DSDDAKHMLN WKLPSQLQKA SAWTAGDFAG RCYEILSSRQ
     LKTEYSDMSI AEVNNALDKL SQVGTEEEQV KIFQRFYRRM NAEEMTWLIR MILRQMKIGA
     TEKTLLDIWH PDAETLFNVS SNLRRVCWEL FDHNIRLEGE NTGLCLMQCF QPQLAQFQDK
     VGSFQKMVNR FKGDSDEDTF WIEEKLDGER MQLHMVEDPD APGGKSFGFW SRKAKDYTYL
     YGKHFHGDAA GALTRFITDA FGKNVKNIIL DGEMVTWDME TDHIVGFGTL KTAAISEKEN
     KTNQETGQRP LFRVFDCVYL NDTLLTQYTL RDRRRALESA VKGVHRRLEV HPYIEARSHT
     EIEPALRKVV AEASEGLVLK NPRSMYCLNQ RNNDWMKVKP EYMSEFGESL DCIVVGGYFG
     SGRRGGAHSS FLCALLTNKS AKPGDPKHEH CWSFFKVGGG FSSDDYAALR GRTQGKWHDW
     DPRRPPPFIE LGGHEQNRQH ERPDQWIRPS DSVVLECKAA SVESSDKFRF ALTLRFPRFK
     QLRTDKRWDQ ALSVQEFLEV KTKVEIEKSE KEKEFKIEQS RRKRARTSKK PLAVMGNDTT
     TTPYAGPKSK IFDALSFYVM TEQMHPVKKS KADLEALIKA NGGRLVQRDS TDKNLIIIAD
     KRLIKVASLE KRATNNIVKP IWIQDCITQN EADTGALPYL LPFEPNRHML YLHDDDQFEF
     ESNVDENGDS YARDIADVEE MRKFLDGMAK PESPATFQRH DFLKQLEDHG KPLEQLKTHM
     FHSVKAVFSY DGDNKEWSLR AQLAKNYFRF GDGLIADNEE EEEGVTHVIV PDEKSLSKRG
     NPRISGLARI VGIGWVEKCW EEGTRLDEER FQWG
//
DBGET integrated database retrieval system