GenomeNet

Database: UniProt/TrEMBL
Entry: M2WYM2_GALSU
LinkDB: M2WYM2_GALSU
Original site: M2WYM2_GALSU 
ID   M2WYM2_GALSU            Unreviewed;       600 AA.
AC   M2WYM2;
DT   01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2013, sequence version 1.
DT   20-DEC-2017, entry version 22.
DE   RecName: Full=Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex {ECO:0000256|RuleBase:RU003423};
DE            EC=2.3.1.- {ECO:0000256|RuleBase:RU003423};
GN   ORFNames=Gasu_33530 {ECO:0000313|EMBL:EME29150.1};
OS   Galdieria sulphuraria (Red alga).
OC   Eukaryota; Rhodophyta; Bangiophyceae; Cyanidiales; Cyanidiaceae;
OC   Galdieria.
OX   NCBI_TaxID=130081 {ECO:0000313|EMBL:EME29150.1, ECO:0000313|Proteomes:UP000030680};
RN   [1] {ECO:0000313|Proteomes:UP000030680}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=074W {ECO:0000313|Proteomes:UP000030680};
RX   PubMed=23471408; DOI=10.1126/science.1231707;
RA   Schonknecht G., Chen W.H., Ternes C.M., Barbier G.G., Shrestha R.P.,
RA   Stanke M., Brautigam A., Baker B.J., Banfield J.F., Garavito R.M.,
RA   Carr K., Wilkerson C., Rensing S.A., Gagneul D., Dickenson N.E.,
RA   Oesterhelt C., Lercher M.J., Weber A.P.;
RT   "Gene transfer from bacteria and archaea facilitated evolution of an
RT   extremophilic eukaryote.";
RL   Science 339:1207-1210(2013).
CC   -!- COFACTOR:
CC       Name=(R)-lipoate; Xref=ChEBI:CHEBI:83088;
CC         Evidence={ECO:0000256|RuleBase:RU003423};
CC   -!- SIMILARITY: Belongs to the 2-oxoacid dehydrogenase family.
CC       {ECO:0000256|RuleBase:RU003423}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; KB454511; EME29150.1; -; Genomic_DNA.
DR   RefSeq; XP_005705670.1; XM_005705613.1.
DR   EnsemblPlants; EME29150; EME29150; Gasu_33530.
DR   GeneID; 17087968; -.
DR   Gramene; EME29150; EME29150; Gasu_33530.
DR   KEGG; gsl:Gasu_33530; -.
DR   KO; K00627; -.
DR   OMA; KAVARNM; -.
DR   Proteomes; UP000030680; Unassembled WGS sequence.
DR   GO; GO:0016746; F:transferase activity, transferring acyl groups; IEA:UniProtKB-KW.
DR   GO; GO:0008152; P:metabolic process; IEA:InterPro.
DR   Gene3D; 4.10.320.10; -; 2.
DR   InterPro; IPR001078; 2-oxoacid_DH_actylTfrase.
DR   InterPro; IPR000089; Biotin_lipoyl.
DR   InterPro; IPR036625; E3-bd_dom_sf.
DR   InterPro; IPR004167; PSBD.
DR   InterPro; IPR011053; Single_hybrid_motif.
DR   Pfam; PF00198; 2-oxoacid_dh; 1.
DR   Pfam; PF00364; Biotin_lipoyl; 2.
DR   Pfam; PF02817; E3_binding; 2.
DR   SUPFAM; SSF47005; SSF47005; 2.
DR   SUPFAM; SSF51230; SSF51230; 2.
DR   PROSITE; PS50968; BIOTINYL_LIPOYL; 1.
DR   PROSITE; PS51826; PSBD; 2.
PE   3: Inferred from homology;
KW   Acyltransferase {ECO:0000256|RuleBase:RU003423};
KW   Complete proteome {ECO:0000313|Proteomes:UP000030680};
KW   Lipoyl {ECO:0000256|RuleBase:RU003423};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030680};
KW   Transferase {ECO:0000256|RuleBase:RU003423,
KW   ECO:0000313|EMBL:EME29150.1}.
FT   DOMAIN      106    181       Lipoyl-binding. {ECO:0000259|PROSITE:
FT                                PS50968}.
FT   DOMAIN      236    273       Peripheral subunit-binding (PSBD).
FT                                {ECO:0000259|PROSITE:PS51826}.
FT   DOMAIN      290    328       Peripheral subunit-binding (PSBD).
FT                                {ECO:0000259|PROSITE:PS51826}.
SQ   SEQUENCE   600 AA;  64128 MW;  CE9BA85A8ECC107E CRC64;
     MVVESDKADM EVEAFDPGYL AAILVDEGGS APVGKTVGLV AEKLEDIEKV KQCGLDCIDS
     GSSSRHDGTT ALETVEFFDS KEDSDFEQRF SSNGSAEQNA MKLPEHVPIL MPTLSSTMTE
     GKIVQWLKKE GDYVKSGEMI MVVESDKADM EVESFDEGYL AHVLYPNESS CPVGTTVAYL
     VSNAADIPQM KQWASESKNR STAPTHKSTQ EASPSVELSA STIPSTSLQG SSSRVIASPY
     ARKIASEKNI SLSGLKGSGE GGRIVAKDVL EASEKGASSN VNQEKPTLVM ATPQAKKLAE
     SFGISLDSIS VGSGPYGRII PADVYKAAGK GPPPPPPHLV DFQATKSSKN GDSSVAPGRV
     SKDNRSRSTE TSSSMMPKGE VAMNSMQKAV VQNMNASLQV PVFRVTYTVN MDAVEALYKK
     LSEKGVSMST ILAKAAALTL RKHSVMNASY GKDSIIYRND IHIAMAVALP DGGLITPVLK
     NADQEDIYTL SKSWRDLVKR ALMKKLSPDE YSTGTFFISN LGMFGVTSFD AILPPGAGAI
     LAVAASKPVV GMQPNGFIGV SKQMQMTITC DHRHIYGAQA ASFLKDFSTL LEENPQELTL
//
DBGET integrated database retrieval system