GenomeNet

Database: UniProt/TrEMBL
Entry: M5XLE0_PRUPE
LinkDB: M5XLE0_PRUPE
Original site: M5XLE0_PRUPE 
ID   M5XLE0_PRUPE            Unreviewed;       404 AA.
AC   M5XLE0;
DT   29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   29-MAY-2013, sequence version 1.
DT   22-NOV-2017, entry version 28.
DE   RecName: Full=Histone deacetylase {ECO:0000256|SAAS:SAAS00894283};
DE            EC=3.5.1.98 {ECO:0000256|SAAS:SAAS00894283};
GN   ORFNames=PRUPE_1G413100 {ECO:0000313|EMBL:ONI33256.1},
GN   PRUPE_ppa006590mg {ECO:0000313|EMBL:EMJ26902.1};
OS   Prunus persica (Peach) (Amygdalus persica).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae;
OC   Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae;
OC   Amygdaleae; Prunus.
OX   NCBI_TaxID=3760 {ECO:0000313|EMBL:EMJ26902.1};
RN   [1] {ECO:0000313|EMBL:ONI33256.1, ECO:0000313|Proteomes:UP000006882}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nemared {ECO:0000313|Proteomes:UP000006882};
RX   PubMed=23525075; DOI=10.1038/ng.2586;
RA   Verde I., Abbott A.G., Scalabrin S., Jung S., Shu S., Marroni F.,
RA   Zhebentyayeva T., Dettori M.T., Grimwood J., Cattonaro F., Zuccolo A.,
RA   Rossini L., Jenkins J., Vendramin E., Meisel L.A., Decroocq V.,
RA   Sosinski B., Prochnik S., Mitros T., Policriti A., Cipriani G.,
RA   Dondini L., Ficklin S., Goodstein D.M., Xuan P., Del Fabbro C.,
RA   Aramini V., Copetti D., Gonzalez S., Horner D.S., Falchi R., Lucas S.,
RA   Mica E., Maldonado J., Lazzari B., Bielenberg D., Pirona R.,
RA   Miculan M., Barakat A., Testolin R., Stella A., Tartarini S.,
RA   Tonutti P., Arus P., Orellana A., Wells C., Main D., Vizzotto G.,
RA   Silva H., Salamini F., Schmutz J., Morgante M., Rokhsar D.S.;
RT   "The high-quality draft genome of peach (Prunus persica) identifies
RT   unique patterns of genetic diversity, domestication and genome
RT   evolution.";
RL   Nat. Genet. 45:487-494(2013).
RN   [2] {ECO:0000313|EMBL:EMJ26902.1}
RP   NUCLEOTIDE SEQUENCE.
RG   The International Peach Genome Initiative;
RA   Verde I., Abbott A.G., Salamini F., Schmutz J., Sosinski B.,
RA   Morgante M., Rokhsar D.S.;
RT   "The genome of Prunis persica.";
RL   Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EMBL:ONI33256.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Verde I., Jenkins J., Dondini L., Micali S., Pagliarani G.,
RA   Vendramin E., Paris R., Aramini V., Gazza L., Rossini L., Bassi D.,
RA   Troggio M., Shu S., Grimwood J.H., Tartarini S., Dettori M.T.,
RA   Schmutz J.;
RT   "WGS assembly of Prunus persica.";
RL   Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: Hydrolysis of an N(6)-acetyl-lysine residue of
CC       a histone to yield a deacetylated histone.
CC       {ECO:0000256|SAAS:SAAS00894227}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|SAAS:SAAS00894298}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; KB638913; EMJ26902.1; -; Genomic_DNA.
DR   EMBL; CM007651; ONI33256.1; -; Genomic_DNA.
DR   EMBL; CM007651; ONI33257.1; -; Genomic_DNA.
DR   RefSeq; XP_007225703.1; XM_007225641.1.
DR   EnsemblPlants; EMJ26902; EMJ26902; PRUPE_ppa006590mg.
DR   GeneID; 18790111; -.
DR   Gramene; EMJ26902; EMJ26902; PRUPE_ppa006590mg.
DR   KEGG; pper:18790111; -.
DR   KO; K11418; -.
DR   OMA; RVFTFSM; -.
DR   OrthoDB; EOG09360ETX; -.
DR   Proteomes; UP000006882; Chromosome g1.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:UniProtKB-EC.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.800.20; -; 1.
DR   InterPro; IPR000286; His_deacetylse.
DR   InterPro; IPR023801; His_deacetylse_dom.
DR   InterPro; IPR037138; His_deacetylse_dom_sf.
DR   InterPro; IPR023696; Ureohydrolase_dom_sf.
DR   Pfam; PF00850; Hist_deacetyl; 1.
DR   PRINTS; PR01270; HDASUPER.
DR   SUPFAM; SSF52768; SSF52768; 1.
PE   4: Predicted;
KW   Chromatin regulator {ECO:0000256|SAAS:SAAS00894233};
KW   Complete proteome {ECO:0000313|Proteomes:UP000006882};
KW   Hydrolase {ECO:0000256|SAAS:SAAS00870288};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Nucleus {ECO:0000256|SAAS:SAAS00894277};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006882};
KW   Transcription {ECO:0000256|SAAS:SAAS00894309};
KW   Transcription regulation {ECO:0000256|SAAS:SAAS00894290};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     20     40       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      124    387       Hist_deacetyl. {ECO:0000259|Pfam:
FT                                PF00850}.
SQ   SEQUENCE   404 AA;  45010 MW;  C20241EF303F2D95 CRC64;
     MKNPVVTSWT ESTRNLFEPV IVLVITFAAI VKLSQSLYRY NLRRRSRARS GTMSSSSSSD
     NGTGVQARRR SRILSSKLYF DIPNSKVPLI YSSAYDITFL GIEKLHPFDS SKWGRICGFL
     LVDNVVDKNC IVEPLEASKN DLLVVHSEAY LNCLKKSANV AMIIEVPHVA VFPNCLVQQK
     VLYPFRNQVG GTILAAKLAK ERGWAINVGG GFHHCSGEKG GGFCAYADIS LCIHFAFERL
     NISRVMIIDL DAHQGNGHET DFANDSRVYI LDVYNPGIYP FDYEARRYID QKVEVVSGTT
     TNEYLRKLDE ALEVSVHSFD PELIVYNAGT DILDGDPLGR LKISPDGITN RDEKVFRFAR
     KRNIPIVMLT SGGYMKSSAR VIADSITNLS NKCLIDTGKN MTAT
//
DBGET integrated database retrieval system