ID M7SI44_EUTLA Unreviewed; 444 AA.
AC M7SI44;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=Putative 3-hydroxyisobutyrate dehydrogenase protein {ECO:0000313|EMBL:EMR63958.1};
GN ORFNames=UCREL1_9087 {ECO:0000313|EMBL:EMR63958.1};
OS Eutypa lata (strain UCR-EL1) (Grapevine dieback disease fungus) (Eutypa
OS armeniacae).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Xylariomycetidae; Xylariales; Diatrypaceae; Eutypa.
OX NCBI_TaxID=1287681 {ECO:0000313|EMBL:EMR63958.1, ECO:0000313|Proteomes:UP000012174};
RN [1] {ECO:0000313|Proteomes:UP000012174}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UCR-EL1 {ECO:0000313|Proteomes:UP000012174};
RX PubMed=23723393; DOI=10.1128/genomeA.00228-13;
RA Blanco-Ulate B., Rolshausen P.E., Cantu D.;
RT "Draft genome sequence of the grapevine dieback fungus Eutypa lata UCR-
RT EL1.";
RL Genome Announc. 1:E0022813-E0022813(2013).
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DR EMBL; KB707130; EMR63958.1; -; Genomic_DNA.
DR RefSeq; XP_007796950.1; XM_007798759.1.
DR AlphaFoldDB; M7SI44; -.
DR STRING; 1287681.M7SI44; -.
DR KEGG; ela:UCREL1_9087; -.
DR eggNOG; KOG0409; Eukaryota.
DR HOGENOM; CLU_035117_1_2_1; -.
DR OMA; QMFMQAS; -.
DR OrthoDB; 1121581at2759; -.
DR Proteomes; UP000012174; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR002204; 3-OH-isobutyrate_DH-rel_CS.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR006115; 6PGDH_NADP-bd.
DR InterPro; IPR029154; HIBADH-like_NADP-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43060; 3-HYDROXYISOBUTYRATE DEHYDROGENASE-LIKE 1, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF14833; NAD_binding_11; 2.
DR Pfam; PF03446; NAD_binding_2; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 2.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00895; 3_HYDROXYISOBUT_DH; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000012174}.
FT DOMAIN 7..165
FT /note="6-phosphogluconate dehydrogenase NADP-binding"
FT /evidence="ECO:0000259|Pfam:PF03446"
FT DOMAIN 176..298
FT /note="3-hydroxyisobutyrate dehydrogenase-like NAD-binding"
FT /evidence="ECO:0000259|Pfam:PF14833"
FT DOMAIN 320..427
FT /note="3-hydroxyisobutyrate dehydrogenase-like NAD-binding"
FT /evidence="ECO:0000259|Pfam:PF14833"
SQ SEQUENCE 444 AA; 46620 MW; 7F312813010ADEAE CRC64;
MESSKPSISF IGLGAMGFGM ATHLVKQGYD VTGFDVWQPT LDRFKEAGGL TAVTPAGAVE
NKNYCVCMVA TAQQAQAVLL DGPNPAVPAL PKGSTLLLCS TVPCAYVQSL AKQLVDAGRD
DIFLVDAPVS GGAARAADGT LSIMAGASDS AIEKGQFLLK ELADEQKLYI VKGGIGAGSN
MKMVHQVLAA NQILSASEAM GFAARLGLDL TTASQAVLKS EGWAWMLEHR LPRMLTAPEF
KPIASALTII VKDTGIITNE AMRYGFPTPM TSTAEQVYFS GIGLGYGPDD DSGMIRIYTE
GKDKAGAVQG QAEGDEAKVN LVVALLKGIH LCSAAESLSF AKKCGLDLDQ VFDLCINAAG
GSTVLQTIGP EMMKLYRGQD LIADGEGLGA LGQQLQTVIE EAQRLKVPLY LGAQALNIIR
LALQHASQSV EKVPRALVAK VWGA
//
