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Database: UniProt/TrEMBL
Entry: P91590_CIOIN A0A1W2VNA7_CIOIN
LinkDB: P91590_CIOIN A0A1W2VNA7_CIOIN
Original site: P91590_CIOIN A0A1W2VNA7_CIOIN 
tr:A0A1W2VNA7_CIOIN : No such data.

ID   P91590_CIOIN            Unreviewed;       766 AA.
AC   P91590; A0A1W2VNA7;
DT   01-MAY-1997, integrated into UniProtKB/TrEMBL.
DT   01-NOV-1998, sequence version 2.
DT   28-MAR-2018, entry version 89.
DE   SubName: Full=Transglutiminase {ECO:0000313|EMBL:CAA71263.1, ECO:0000313|RefSeq:NP_001027712.1};
GN   Name=tgm2 {ECO:0000313|RefSeq:NP_001027712.1};
OS   Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis).
OC   Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Enterogona;
OC   Phlebobranchia; Cionidae; Ciona.
OX   NCBI_TaxID=7719 {ECO:0000313|EMBL:CAA71263.1};
RN   [1] {ECO:0000313|EMBL:CAA71263.1, ECO:0000313|RefSeq:NP_001027712.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=9187361; DOI=10.1016/S0014-5793(97)00342-6;
RA   Cariello L., Ristoratore F., Zanetti L.;
RT   "A new transglutaminase-like from the ascidian Ciona intestinalis.";
RL   FEBS Lett. 408:171-176(1997).
RN   [2] {ECO:0000313|EMBL:CAA71263.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Cariello L.;
RL   Submitted (SEP-1998) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|RefSeq:NP_001027712.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (FEB-2018) to UniProtKB.
CC   -!- COFACTOR:
CC       Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC         Evidence={ECO:0000256|PIRSR:PIRSR000459-2};
CC       Note=Binds 1 Ca(2+) ion per subunit.
CC       {ECO:0000256|PIRSR:PIRSR000459-2};
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DR   EMBL; Y10212; CAA71263.1; -; mRNA.
DR   RefSeq; NP_001027712.1; NM_001032540.1.
DR   UniGene; Cin.22973; -.
DR   ProteinModelPortal; P91590; -.
DR   GeneID; 445739; -.
DR   KEGG; cin:445739; -.
DR   CTD; 7052; -.
DR   eggNOG; ENOG410IFMV; Eukaryota.
DR   eggNOG; ENOG410XQEZ; LUCA.
DR   HOGENOM; HOG000231695; -.
DR   KO; K05625; -.
DR   GO; GO:0003810; F:protein-glutamine gamma-glutamyltransferase activity; IEA:InterPro.
DR   GO; GO:0018149; P:peptide cross-linking; IEA:InterPro.
DR   Gene3D; 2.60.40.10; -; 3.
DR   Gene3D; 3.90.260.10; -; 1.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR002931; Transglutaminase-like.
DR   InterPro; IPR036985; Transglutaminase-like_sf.
DR   InterPro; IPR023608; Transglutaminase_animal.
DR   InterPro; IPR036238; Transglutaminase_C_sf.
DR   InterPro; IPR001102; Transglutaminase_N.
DR   Pfam; PF01841; Transglut_core; 1.
DR   Pfam; PF00868; Transglut_N; 1.
DR   PIRSF; PIRSF000459; TGM_EBP42; 1.
DR   SMART; SM00460; TGc; 1.
DR   SUPFAM; SSF49309; SSF49309; 2.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   2: Evidence at transcript level;
KW   Calcium {ECO:0000256|PIRSR:PIRSR000459-2};
KW   Metal-binding {ECO:0000256|PIRSR:PIRSR000459-2}.
FT   DOMAIN      340    432       TGc. {ECO:0000259|SMART:SM00460}.
FT   ACT_SITE    348    348       {ECO:0000256|PIRSR:PIRSR000459-1}.
FT   ACT_SITE    406    406       {ECO:0000256|PIRSR:PIRSR000459-1}.
FT   ACT_SITE    429    429       {ECO:0000256|PIRSR:PIRSR000459-1}.
FT   METAL       469    469       Calcium. {ECO:0000256|PIRSR:PIRSR000459-
FT                                2}.
FT   METAL       471    471       Calcium. {ECO:0000256|PIRSR:PIRSR000459-
FT                                2}.
FT   METAL       519    519       Calcium. {ECO:0000256|PIRSR:PIRSR000459-
FT                                2}.
FT   METAL       524    524       Calcium. {ECO:0000256|PIRSR:PIRSR000459-
FT                                2}.
SQ   SEQUENCE   766 AA;  87194 MW;  7F90D921D87FDD1D CRC64;
     MSRFRRRWFV IDAENAEEVN EFLDEHPRFL GEYIDRNPHL LDNYVIDNVD EETIQKWLDK
     VSGPAPTEVL QILRVNYKKE TNCVDHHTDK YIHNSLVVRR ATTFDLGLVF KNRNYRPAKD
     DIVLEFTIGS DPTIKNETKI RVPVGDSLQG SKWTCMKINE DEVTKEVTLQ VNIPPDAIIG
     RYKLTVEVAT ELKDGRQKER KVKPDIVVLF NPFKPADPVY MESSVEREEY VLNDTGRIYV
     GQWYRIGAKD WLFGQFEEGI LDIALKLLRE HTNAQKNATK SLKKRASPAY CSRLLSAMVN
     CNDDNGVLWG RWDGKYEEGV KPTTWSGSVA ILKQWNRTKM NPVKYGQCWV FSGLLTTVLR
     ALGIPARSIT NFNSAHDTEY NMTIDKFLTE DGESAEGTGD SIWNFHVWNE GFFRRPDLPK
     GYDGWQAVDA TPQEESSGVM QCGPAPIKAI KNGEIYIGSD TNFVFAEVNA DRVFWEVNDE
     GEVTKMVKND KRHVGRNIST KAVGSDERED VTLQYKFAEG SEEERVAFER AYAHGRKAPY
     HDKFVLEDEG NIKIDINPVG DVINGSDVSI SVKVTNAKGV DCDATITTVI HTMLNNEERK
     RLLKRSRGTR KIAAGKDDVE SFKFGFGDYG RHLSDENVIR VTTTVRVKET NKLYVDQYDI
     QIESPQCLEL ICADELKVRE YQPIRFKITN PLKVAMTSAV FSLQGSGISS GKSFEVPSPI
     EPGETYTSPE MEVRPYRSSR ATTILGDFDC NEIWNIKARK RVAVNF
//
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