ID Q00UC7_OSTTA Unreviewed; 1048 AA.
AC Q00UC7;
DT 14-NOV-2006, integrated into UniProtKB/TrEMBL.
DT 14-NOV-2006, sequence version 1.
DT 27-MAR-2024, entry version 103.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=OT_ostta16g01200 {ECO:0000313|EMBL:CAL58122.1};
OS Ostreococcus tauri.
OC Eukaryota; Viridiplantae; Chlorophyta; Mamiellophyceae; Mamiellales;
OC Bathycoccaceae; Ostreococcus.
OX NCBI_TaxID=70448 {ECO:0000313|EMBL:CAL58122.1, ECO:0000313|Proteomes:UP000009170};
RN [1] {ECO:0000313|Proteomes:UP000009170}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OTTH0595 {ECO:0000313|Proteomes:UP000009170};
RX PubMed=16868079; DOI=10.1073/pnas.0604795103;
RA Derelle E., Ferraz C., Rombauts S., Rouze P., Worden A.Z., Robbens S.,
RA Partensky F., Degroeve S., Echeynie S., Cooke R., Saeys Y., Wuyts J.,
RA Jabbari K., Bowler C., Panaud O., Piegu B., Ball S.G., Ral J.-P.,
RA Bouget F.-Y., Piganeau G., De Baets B., Picard A., Delseny M., Demaille J.,
RA Van de Peer Y., Moreau H.;
RT "Genome analysis of the smallest free-living eukaryote Ostreococcus tauri
RT unveils many unique features.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:11647-11652(2006).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CAL58122.1}.
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DR EMBL; CAID01000016; CAL58122.1; -; Genomic_DNA.
DR RefSeq; XP_003083573.1; XM_003083525.1.
DR AlphaFoldDB; Q00UC7; -.
DR STRING; 70448.Q00UC7; -.
DR GeneID; 9830947; -.
DR KEGG; ota:OT_ostta16g01200; -.
DR InParanoid; Q00UC7; -.
DR OMA; GNCATIV; -.
DR OrthoDB; 124793at2759; -.
DR Proteomes; UP000009170; Chromosome 16.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0016818; F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR CDD; cd18788; SF2_C_XPD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR006555; ATP-dep_Helicase_C.
DR InterPro; IPR045028; DinG/Rad3-like.
DR InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR InterPro; IPR014013; Helic_SF1/SF2_ATP-bd_DinG/Rad3.
DR InterPro; IPR006554; Helicase-like_DEXD_c2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010614; RAD3-like_helicase_DEAD.
DR InterPro; IPR013020; Rad3/Chl1-like.
DR InterPro; IPR001841; Znf_RING.
DR NCBIfam; TIGR00604; rad3; 1.
DR PANTHER; PTHR11472; DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER; 1.
DR PANTHER; PTHR11472:SF34; REGULATOR OF TELOMERE ELONGATION HELICASE 1; 1.
DR Pfam; PF06733; DEAD_2; 1.
DR Pfam; PF13307; Helicase_C_2; 1.
DR SMART; SM00488; DEXDc2; 1.
DR SMART; SM00491; HELICc2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR PROSITE; PS51193; HELICASE_ATP_BIND_2; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:CAL58122.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000009170};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00175};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00175}.
FT DOMAIN 16..317
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51193"
FT DOMAIN 993..1035
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
SQ SEQUENCE 1048 AA; 116706 MW; 780F0A2DDFEB01D8 CRC64;
MPDYAFACVD ATGANRKFTV SFPYDAYDAQ IVFIERALEA MCRKQSALLE SPTGTGKTLC
LLSAALAYAR NEGRAKKRRA RAREKASTSE TVTEEFVDAE VRRERERAPT IVYATRTHSQ
VRQVLGELKV LDSNTRATTL ASRKHACARE DVRALVGDAQ NNRCSKLVAE RKCGAKNVLD
MSLNRKGIGE KFDVFEGGVR DIEDLVIAAQ KSRGPCPFYL SRTKCADAEI IFMPYNYLLN
DTVRRGLDIV WEDAVVIVDE AHNLESSAAD SMSYSLTAAK LAKAIQETNS AWETKLTVDD
NDEEGVLRDD QKELFKRGMG EEASAFGSND VLELGRTLLQ LEEVLDGVCR EASTKSGKSG
TLGECVEDGA FIYNLLERVG ITQFTYQRAV TIMKGAAKMV QLGSDFMEAA TGTHKETPLT
EIANFIERLF TKRADQYFVT RVGPDTDNFK TSQRQRQGPT LSYWCFFPGL CLKELIEKNV
GSFLLASGTL SPMESFSSEL AMEFPVRLEN PHVIQRNQIW GGVLTHGPGG NVLNSSFRFR
DTDNYKKEIG SVILSTAKIV PDGLLVFFPS YGVMNSCIDH WRFVEGGLWA GIEASKTCFI
EPSNSEEFQE CYKRYNEALN DGTRRGAIFF AVCRGKVSEG IDFADKACRG VILTGIPYAG
AKDPLVMHKR SFLDKRRAND GESYSGNEWY SQTAMRAVNQ ALGRAIRHKN DFGAVILADE
RFANENARNQ LSLWLRPSIQ VHSVFNSVVS GLRDFFQSNV GSVASAKPAP AKFVDIAVVK
AKAKADTMAR KEKSKASIAS LVRQFSKDQG DDEDEEARKK FMLVSKRTVP LQAKKLDLFG
AAREKQTREA QRKSPLLMQL ARSRGEETDN VGQVIDDENA ELPSEERTKL FMRRAKLELS
RDAYNELVSH IDKVNTDEFD IRDLLRVASR VLKAPENPKG LYALFGEFVP SSHKPIYEKH
RQALIERQEK VKAQKIAAGG PSQLVVVAPP NACVVCSHPC DKPFFASACK HVACYKCWLD
KVVKPRGPGV CPSCSAEVLK RHLEKKFF
//
