ID Q0KAF1_CUPNH Unreviewed; 477 AA.
AC Q0KAF1;
DT 03-OCT-2006, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2006, sequence version 1.
DT 27-MAR-2024, entry version 100.
DE SubName: Full=Putative Lactaldehyde dehydrogenase {ECO:0000313|EMBL:CAJ93020.1};
DE EC=1.2.1.22 {ECO:0000313|EMBL:CAJ93020.1};
GN OrderedLocusNames=H16_A1919 {ECO:0000313|EMBL:CAJ93020.1};
OS Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442
OS / H16 / Stanier 337) (Ralstonia eutropha).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Cupriavidus.
OX NCBI_TaxID=381666 {ECO:0000313|EMBL:CAJ93020.1, ECO:0000313|Proteomes:UP000008210};
RN [1] {ECO:0000313|EMBL:CAJ93020.1, ECO:0000313|Proteomes:UP000008210}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier
RC 337 {ECO:0000313|Proteomes:UP000008210};
RX PubMed=16964242; DOI=10.1038/nbt1244;
RA Pohlmann A., Fricke W.F., Reinecke F., Kusian B., Liesegang H., Cramm R.,
RA Eitinger T., Ewering C., Potter M., Schwartz E., Strittmatter A., Voss I.,
RA Gottschalk G., Steinbuechel A., Friedrich B., Bowien B.;
RT "Genome sequence of the bioplastic-producing 'Knallgas' bacterium Ralstonia
RT eutropha H16.";
RL Nat. Biotechnol. 24:1257-1262(2006).
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|RuleBase:RU003345}.
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DR EMBL; AM260479; CAJ93020.1; -; Genomic_DNA.
DR RefSeq; WP_010809534.1; NZ_CP039287.1.
DR AlphaFoldDB; Q0KAF1; -.
DR STRING; 381666.H16_A1919; -.
DR GeneID; 57644037; -.
DR KEGG; reh:H16_A1919; -.
DR PATRIC; fig|381666.6.peg.2325; -.
DR eggNOG; COG1012; Bacteria.
DR HOGENOM; CLU_005391_0_0_4; -.
DR OrthoDB; 6187633at2; -.
DR Proteomes; UP000008210; Chromosome 1.
DR GO; GO:0008911; F:lactaldehyde dehydrogenase activity; IEA:UniProtKB-EC.
DR CDD; cd07138; ALDH_CddD_SSP0762; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR PANTHER; PTHR42804; ALDEHYDE DEHYDROGENASE; 1.
DR PANTHER; PTHR42804:SF1; ALDEHYDE DEHYDROGENASE-RELATED; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003345};
KW Reference proteome {ECO:0000313|Proteomes:UP000008210}.
FT DOMAIN 13..469
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 245
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ SEQUENCE 477 AA; 50357 MW; D63853D0CC26D46A CRC64;
MQQRDKLFIN GKWVAPHGNG TIDVIHSATE AVMGTIPEGS ARDAEDAIQA ARAAFDSWSA
TPPAVRAGYI AKIAEGLKAR SEELAQLIAG EVGMPIKLAR AIQVGGPVYN WGQAAKLLDG
FRFEEEVGNS LVVREPVGVV GAITPWNYPL NQITLKVAPA LAAGCTVVLK PSEVAPLNAF
VLAEVIEAAG LPPGVFNLVT GYGPVVGEVL ASHPEVDMVS FTGSTRAGKR VSELASQTVK
RVALELGGKS ASVILDDADL PSAVKGTINA CFLNSGQTCS AHTRMLVPRA RYDEVKAIAQ
KVVEGFTVGD PLQEASKLGP LISAVQKDRV TGYIRRGLEE GAELVAGGPD TPEGLDKGFF
VKPTVLGNVE PRATVAQEEI FGPVLSIICY DTEEDAVRIA NDSIYGLGGG VWSGDEARAI
RVARRIRTGQ VDINGGPFNM QAPFGGYKQS GNGREAGKYG LEEFLEYKSL QLKKPAA
//
