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Database: UniProt/TrEMBL
Entry: Q13HI9_PARXL
LinkDB: Q13HI9_PARXL
Original site: Q13HI9_PARXL 
ID   Q13HI9_PARXL            Unreviewed;       461 AA.
AC   Q13HI9;
DT   22-AUG-2006, integrated into UniProtKB/TrEMBL.
DT   22-AUG-2006, sequence version 1.
DT   25-OCT-2017, entry version 75.
DE   RecName: Full=Glutamate decarboxylase {ECO:0000256|RuleBase:RU361171};
DE            EC=4.1.1.15 {ECO:0000256|RuleBase:RU361171};
GN   ORFNames=Bxe_C0551 {ECO:0000313|EMBL:ABE36450.1};
OS   Paraburkholderia xenovorans (strain LB400).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Paraburkholderia.
OX   NCBI_TaxID=266265 {ECO:0000313|EMBL:ABE36450.1, ECO:0000313|Proteomes:UP000001817};
RN   [1] {ECO:0000313|EMBL:ABE36450.1, ECO:0000313|Proteomes:UP000001817}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LB400 {ECO:0000313|EMBL:ABE36450.1,
RC   ECO:0000313|Proteomes:UP000001817};
RX   PubMed=17030797; DOI=10.1073/pnas.0606924103;
RA   Chain P.S., Denef V.J., Konstantinidis K.T., Vergez L.M., Agullo L.,
RA   Reyes V.L., Hauser L., Cordova M., Gomez L., Gonzalez M., Land M.,
RA   Lao V., Larimer F., LiPuma J.J., Mahenthiralingam E., Malfatti S.A.,
RA   Marx C.J., Parnell J.J., Ramette A., Richardson P., Seeger M.,
RA   Smith D., Spilker T., Sul W.J., Tsoi T.V., Ulrich L.E., Zhulin I.B.,
RA   Tiedje J.M.;
RT   "Burkholderia xenovorans LB400 harbors a multi-replicon, 9.73-Mbp
RT   genome shaped for versatility.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:15280-15287(2006).
CC   -!- CATALYTIC ACTIVITY: L-glutamate = 4-aminobutanoate + CO(2).
CC       {ECO:0000256|RuleBase:RU361171}.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|PIRSR:PIRSR602129-50,
CC         ECO:0000256|RuleBase:RU361171};
CC   -!- SIMILARITY: Belongs to the group II decarboxylase family.
CC       {ECO:0000256|RuleBase:RU361171}.
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DR   EMBL; CP000272; ABE36450.1; -; Genomic_DNA.
DR   RefSeq; WP_011493706.1; NZ_CP008761.1.
DR   ProteinModelPortal; Q13HI9; -.
DR   STRING; 266265.Bxe_C0551; -.
DR   EnsemblBacteria; ABE36450; ABE36450; Bxe_C0551.
DR   GeneID; 4010065; -.
DR   KEGG; bxb:DR64_7895; -.
DR   KEGG; bxe:Bxe_C0551; -.
DR   PATRIC; fig|266265.5.peg.8312; -.
DR   eggNOG; ENOG4105CVK; Bacteria.
DR   eggNOG; COG0076; LUCA.
DR   HOGENOM; HOG000070228; -.
DR   KO; K01580; -.
DR   OMA; RPNLVMG; -.
DR   OrthoDB; POG091H06F5; -.
DR   Proteomes; UP000001817; Chromosome 3.
DR   GO; GO:0004351; F:glutamate decarboxylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0006536; P:glutamate metabolic process; IEA:InterPro.
DR   Gene3D; 3.40.640.10; -; 1.
DR   Gene3D; 3.90.1150.10; -; 1.
DR   InterPro; IPR010107; Glutamate_decarboxylase.
DR   InterPro; IPR002129; PyrdxlP-dep_de-COase.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major_sub1.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_sub2.
DR   PANTHER; PTHR43321; PTHR43321; 1.
DR   Pfam; PF00282; Pyridoxal_deC; 1.
DR   SUPFAM; SSF53383; SSF53383; 1.
DR   TIGRFAMs; TIGR01788; Glu-decarb-GAD; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000001817};
KW   Decarboxylase {ECO:0000256|RuleBase:RU361171};
KW   Lyase {ECO:0000256|RuleBase:RU361171, ECO:0000313|EMBL:ABE36450.1};
KW   Pyridoxal phosphate {ECO:0000256|PIRSR:PIRSR602129-50,
KW   ECO:0000256|RuleBase:RU361171};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001817}.
FT   MOD_RES     274    274       N6-(pyridoxal phosphate)lysine.
FT                                {ECO:0000256|PIRSR:PIRSR602129-50}.
SQ   SEQUENCE   461 AA;  51118 MW;  632CBE2C37B4513E CRC64;
     MTFLKSPPPT PDAVADEYAA MISGSSLPKY RIPEASSDRR AVFDLVRDEL FMDGNSRQNV
     ATFCTTYADD EVRRLMDLSI DKNMIDKDEY PQTAEIEMRC VHMLADLWHA TKSWKTTGCS
     TTGSSEACML GGLALKWQWK KRREAQGKPT GKPNFVCGPV QVCWAKFARY FDVEMRQVPL
     SGDATGLRPE DLAQYCDENT IGVVATLGIT FTCVYEPVKA LAGALDALQA NVGLDIPIHV
     DAASGGFVAP FIQPDLEWDF SVPRVKSINA SGHKYGLAPL GVGWIVWRST QDLPDELIFR
     VDYLGGDMPT FALNFSRPAG QIIAQYYMLL RLGREGYRHI QQECADTAQA LADGLAKIDA
     LDMIYDGRGA LPAVCYKLKH PDTAGFTLFD LSDRVRMRGW QIASYELPAG REDTIVQRVL
     IRRGVTRDMA AMLLEDIKHA IAHLTKNPVP NSTAGPTFHH D
//
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