ID   Q16VW4_AEDAE            Unreviewed;       453 AA.
AC   Q16VW4;
DT   25-JUL-2006, integrated into UniProtKB/TrEMBL.
DT   25-JUL-2006, sequence version 1.
DT   03-APR-2013, entry version 42.
DE   SubName: Full=AAEL009387-PA;
GN   ORFNames=AAEL009387;
OS   Aedes aegypti (Yellowfever mosquito) (Culex aegypti).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea;
OC   Culicidae; Culicinae; Aedini; Aedes; Stegomyia.
OX   NCBI_TaxID=7159;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LVPib12;
RX   PubMed=17510324; DOI=10.1126/science.1138878;
RA   Nene V., Wortman J.R., Lawson D., Haas B., Kodira C., Tu Z.J.,
RA   Loftus B., Xi Z., Megy K., Grabherr M., Ren Q., Zdobnov E.M.,
RA   Lobo N.F., Campbell K.S., Brown S.E., Bonaldo M.F., Zhu J.,
RA   Sinkins S.P., Hogenkamp D.G., Amedeo P., Arensburger P.,
RA   Atkinson P.W., Bidwell S., Biedler J., Birney E., Bruggner R.V.,
RA   Costas J., Coy M.R., Crabtree J., Crawford M., Debruyn B.,
RA   Decaprio D., Eiglmeier K., Eisenstadt E., El-Dorry H., Gelbart W.M.,
RA   Gomes S.L., Hammond M., Hannick L.I., Hogan J.R., Holmes M.H.,
RA   Jaffe D., Johnston J.S., Kennedy R.C., Koo H., Kravitz S.,
RA   Kriventseva E.V., Kulp D., Labutti K., Lee E., Li S., Lovin D.D.,
RA   Mao C., Mauceli E., Menck C.F., Miller J.R., Montgomery P., Mori A.,
RA   Nascimento A.L., Naveira H.F., Nusbaum C., O'leary S., Orvis J.,
RA   Pertea M., Quesneville H., Reidenbach K.R., Rogers Y.H., Roth C.W.,
RA   Schneider J.R., Schatz M., Shumway M., Stanke M., Stinson E.O.,
RA   Tubio J.M., Vanzee J.P., Verjovski-Almeida S., Werner D., White O.,
RA   Wyder S., Zeng Q., Zhao Q., Zhao Y., Hill C.A., Raikhel A.S.,
RA   Soares M.B., Knudson D.L., Lee N.H., Galagan J., Salzberg S.L.,
RA   Paulsen I.T., Dimopoulos G., Collins F.H., Birren B.,
RA   Fraser-Liggett C.M., Severson D.W.;
RT   "Genome sequence of Aedes aegypti, a major arbovirus vector.";
RL   Science 316:1718-1723(2007).
CC   -!- SIMILARITY: Belongs to the hexokinase family.
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DR   EMBL; CH477579; EAT38749.1; -; Genomic_DNA.
DR   RefSeq; XP_001660031.1; XM_001659981.1.
DR   UniGene; Aae.6367; -.
DR   ProteinModelPortal; Q16VW4; -.
DR   EnsemblMetazoa; AAEL009387-RA; AAEL009387-PA; AAEL009387.
DR   GeneID; 5571932; -.
DR   KEGG; aag:AaeL_AAEL009387; -.
DR   VectorBase; AAEL009387; Aedes aegypti.
DR   eggNOG; COG5026; -.
DR   HOGENOM; HOG000162670; -.
DR   KO; K00844; -.
DR   OrthoDB; EOG4XWDD2; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004396; F:hexokinase activity; IEA:InterPro.
DR   GO; GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
DR   InterPro; IPR001312; Hexokinase.
DR   InterPro; IPR022673; Hexokinase_C.
DR   InterPro; IPR019807; Hexokinase_CS.
DR   InterPro; IPR022672; Hexokinase_N.
DR   PANTHER; PTHR19443; PTHR19443; 1.
DR   Pfam; PF00349; Hexokinase_1; 1.
DR   Pfam; PF03727; Hexokinase_2; 1.
DR   PRINTS; PR00475; HEXOKINASE.
DR   PROSITE; PS00378; HEXOKINASES; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Glycolysis; Kinase;
KW   Nucleotide-binding; Reference proteome; Transferase.
SQ   SEQUENCE   453 AA;  50499 MW;  65205E04165F71A1 CRC64;
     MGIIKDNTSK IREQCQELIL SDKQIEEIMR RLLKEINRGL GKATQPEADI KCFITYVQDL
     PNGKEKGKFL ALDLGGTNFR VLLIHLKDEN DFEMLSKIYA IPQSIMLGSG TQLFDHIAEC
     LANFMKEHSV YEEKLPLGFT FSFPLTQLGL TKGILARWTK GFNCSGVVGE DVVQLLKDAI
     ARRGDVQIEI CAILNDTTGT LMSCAWKNHN CRIGLIVGTG SNACYVEKVE NCEMFDGPKD
     PKKEHVLINT EWGAFGDNGA LDFVRTEYDR EIDHFSINPG RQIQEKMISG MYMGELARLA
     IVKFTRAGLL FGGVGSDILF KRGQFFTKYV SEIESDKPGT YMYCRDVLDE LGLEHATDED
     CANVRYICEC VSSRAAHLVS AGIAALINKM DEKSVTVGVD GSVYRFHPKF HDLMKAKIRQ
     FVKPDISFDL MLSEDGSGRG AALVAAVACR EAH
//