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Database: UniProt/TrEMBL
Entry: Q173Z9_AEDAE
LinkDB: Q173Z9_AEDAE
Original site: Q173Z9_AEDAE 
ID   Q173Z9_AEDAE            Unreviewed;       804 AA.
AC   Q173Z9;
DT   25-JUL-2006, integrated into UniProtKB/TrEMBL.
DT   25-JUL-2006, sequence version 1.
DT   27-SEP-2017, entry version 78.
DE   SubName: Full=AAEL006978-PA {ECO:0000313|EMBL:EAT41371.1};
DE   SubName: Full=Protein-glutamine gamma-glutamyltransferase {ECO:0000313|VectorBase:AAEL006978-PA};
GN   Name=5568609 {ECO:0000313|VectorBase:AAEL006978-PA};
GN   ORFNames=AAEL006978 {ECO:0000313|EMBL:EAT41371.1};
OS   Aedes aegypti (Yellowfever mosquito) (Culex aegypti).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicoidea;
OC   Culicidae; Culicinae; Aedini; Aedes; Stegomyia.
OX   NCBI_TaxID=7159 {ECO:0000313|EMBL:EAT41371.1, ECO:0000313|Proteomes:UP000008820};
RN   [1] {ECO:0000313|EMBL:EAT41371.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Liverpool {ECO:0000313|EMBL:EAT41371.1};
RA   Loftus B.J., Nene V.M., Hannick L.I., Bidwell S., Haas B., Amedeo P.,
RA   Orvis J., Wortman J.R., White O.R., Salzberg S., Shumway M., Koo H.,
RA   Zhao Y., Holmes M., Miller J., Schatz M., Pop M., Pai G.,
RA   Utterback T., Rogers Y.-H., Kravitz S., Fraser C.M.;
RL   Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:EAT41371.1, ECO:0000313|Proteomes:UP000008820, ECO:0000313|VectorBase:AAEL006978-PA}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Liverpool {ECO:0000313|EMBL:EAT41371.1}, and Liverpool/LVPib12
RC   {ECO:0000313|Proteomes:UP000008820,
RC   ECO:0000313|VectorBase:AAEL006978-PA};
RX   PubMed=17510324; DOI=10.1126/science.1138878;
RA   Nene V., Wortman J.R., Lawson D., Haas B.J., Kodira C.D., Tu Z.J.,
RA   Loftus B.J., Xi Z., Megy K., Grabherr M., Ren Q., Zdobnov E.M.,
RA   Lobo N.F., Campbell K.S., Brown S.E., Bonaldo M.F., Zhu J.,
RA   Sinkins S.P., Hogenkamp D.G., Amedeo P., Arensburger P.,
RA   Atkinson P.W., Bidwell S.L., Biedler J., Birney E., Bruggner R.V.,
RA   Costas J., Coy M.R., Crabtree J., Crawford M., DeBruyn B.,
RA   DeCaprio D., Eiglmeier K., Eisenstadt E., El-Dorry H., Gelbart W.M.,
RA   Gomes S.L., Hammond M., Hannick L.I., Hogan J.R., Holmes M.H.,
RA   Jaffe D., Johnston S.J., Kennedy R.C., Koo H., Kravitz S.,
RA   Kriventseva E.V., Kulp D., Labutti K., Lee E., Li S., Lovin D.D.,
RA   Mao C., Mauceli E., Menck C.F., Miller J.R., Montgomery P., Mori A.,
RA   Nascimento A.L., Naveira H.F., Nusbaum C., O'Leary S.B., Orvis J.,
RA   Pertea M., Quesneville H., Reidenbach K.R., Rogers Y.-H.C., Roth C.W.,
RA   Schneider J.R., Schatz M., Shumway M., Stanke M., Stinson E.O.,
RA   Tubio J.M.C., Vanzee J.P., Verjovski-Almeida S., Werner D.,
RA   White O.R., Wyder S., Zeng Q., Zhao Q., Zhao Y., Hill C.A.,
RA   Raikhel A.S., Soares M.B., Knudson D.L., Lee N.H., Galagan J.,
RA   Salzberg S.L., Paulsen I.T., Dimopoulos G., Collins F.H., Bruce B.,
RA   Fraser-Liggett C.M., Severson D.W.;
RT   "Genome sequence of Aedes aegypti, a major arbovirus vector.";
RL   Science 316:1718-1723(2007).
RN   [3] {ECO:0000313|EMBL:EAT41371.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Liverpool {ECO:0000313|EMBL:EAT41371.1};
RG   VectorBase;
RL   Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
RN   [4] {ECO:0000313|VectorBase:AAEL006978-PA}
RP   IDENTIFICATION.
RC   STRAIN=Liverpool/LVPib12 {ECO:0000313|VectorBase:AAEL006978-PA};
RG   VectorBase;
RL   Submitted (FEB-2017) to UniProtKB.
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DR   EMBL; CH477415; EAT41371.1; -; Genomic_DNA.
DR   RefSeq; XP_001652440.1; XM_001652390.1.
DR   UniGene; Aae.10721; -.
DR   ProteinModelPortal; Q173Z9; -.
DR   STRING; 7159.AAEL006978-PA; -.
DR   EnsemblMetazoa; AAEL006978-RA; AAEL006978-PA; AAEL006978.
DR   KEGG; aag:AaeL_AAEL006978; -.
DR   VectorBase; AAEL006978-RA; AAEL006978-PA; AAEL006978.
DR   eggNOG; ENOG410IFMV; Eukaryota.
DR   eggNOG; ENOG410XQEZ; LUCA.
DR   HOGENOM; HOG000231695; -.
DR   InParanoid; Q173Z9; -.
DR   KO; K05619; -.
DR   OMA; VIFEEYY; -.
DR   OrthoDB; EOG091G02XQ; -.
DR   PhylomeDB; Q173Z9; -.
DR   Proteomes; UP000008820; Unassembled WGS sequence.
DR   GO; GO:0003810; F:protein-glutamine gamma-glutamyltransferase activity; IEA:InterPro.
DR   GO; GO:0018149; P:peptide cross-linking; IEA:InterPro.
DR   Gene3D; 2.60.40.10; -; 3.
DR   Gene3D; 3.90.260.10; -; 1.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR002931; Transglutaminase-like.
DR   InterPro; IPR023608; Transglutaminase_animal.
DR   InterPro; IPR008958; Transglutaminase_C.
DR   InterPro; IPR001102; Transglutaminase_N.
DR   Pfam; PF00927; Transglut_C; 2.
DR   Pfam; PF01841; Transglut_core; 1.
DR   Pfam; PF00868; Transglut_N; 1.
DR   PIRSF; PIRSF000459; TGM_EBP42; 1.
DR   SMART; SM00460; TGc; 1.
DR   SUPFAM; SSF49309; SSF49309; 2.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000008820};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008820}.
FT   DOMAIN      355    452       TGc. {ECO:0000259|SMART:SM00460}.
FT   ACT_SITE    363    363       {ECO:0000256|PIRSR:PIRSR000459-1}.
FT   ACT_SITE    422    422       {ECO:0000256|PIRSR:PIRSR000459-1}.
FT   ACT_SITE    449    449       {ECO:0000256|PIRSR:PIRSR000459-1}.
SQ   SEQUENCE   804 AA;  90490 MW;  BBFC45B875D451BA CRC64;
     MGNKCSTSSC GGCFGGCSGE HKASDSCCSC CGMRFRRVWK PARVDTGERG RLMAGHNPLA
     KPMMEMKDMD VVDAPSADVL TIKKVDMCID ENGKLHHTKR YELMTRDGQV GPPARLVVRR
     GQAFRLRLHC DRPFDRSRDA MSLIFTVDGE ERPTHGHGSL VGVALQQYRH LIEDPLEWGA
     AIDFISGDML EILVKPAATA AVTRWKLDFD TKLLSEGFGK SYSLPQSFYL LFNPWCKDDQ
     VYLEEKPLRD ECVMNDTTLI WRGSYNRLRP SVWKFGQFER HVLDCSLLLI DKVGKVSATH
     RGDPIRVCRA ISAAVNSPDD DGALLGNWSG DFSGGTAPTK WVGSVEIMQQ YYKKQKPVKF
     GQCWVFAGVV STIARAIGIP SRVVTNYSSA HDTQASLTVD YFVDQNGKVM EELNSDSIWN
     YHVWNEVWMQ RPDLGISSDG DYGGWQAIDS TPQEMSDGMF RCGPASVLAV KLGEIAKPYD
     NNFLFAEVNA DKVFWRYTGP AHPLKLLRKD VLGIGHFIST KAVGKWERED ITSSYKFAEK
     SQEERDTMMK ALKQANSAFS RYYLNEDFNE VYFNFELRDD IKIGENFSVI LQIKNRSSEM
     VHVVKGSLNV ETVLYTGKER EMVKSDHFTI TVKPNTEEFV KLVVTFEEYF KKLRDQAAFN
     ISCFATVEET EYEFFAQDDF RVRKPDIKIK LSDAPVSQSP VDVTISLLNP LPIPLRKGIF
     HVEGSGIESP LIFKHSDVAV GETITNTFSL TPEFAGRATI AAKFTSKELD DVDGFLAFEA
     KPRPEDVLME TSDNEIIART DVID
//
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