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Database: UniProt/TrEMBL
Entry: Q17KU1_AEDAE
LinkDB: Q17KU1_AEDAE
Original site: Q17KU1_AEDAE 
ID   Q17KU1_AEDAE            Unreviewed;       495 AA.
AC   Q17KU1;
DT   25-JUL-2006, integrated into UniProtKB/TrEMBL.
DT   25-JUL-2006, sequence version 1.
DT   27-SEP-2017, entry version 79.
DE   SubName: Full=AAEL001567-PA {ECO:0000313|EMBL:EAT47316.1};
DE   SubName: Full=Myocyte-specific enhancer factor 2d {ECO:0000313|VectorBase:AAEL001567-PA};
GN   Name=5571277 {ECO:0000313|VectorBase:AAEL001567-PA};
GN   ORFNames=AAEL001567 {ECO:0000313|EMBL:EAT47316.1};
OS   Aedes aegypti (Yellowfever mosquito) (Culex aegypti).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicoidea;
OC   Culicidae; Culicinae; Aedini; Aedes; Stegomyia.
OX   NCBI_TaxID=7159 {ECO:0000313|EMBL:EAT47316.1, ECO:0000313|Proteomes:UP000008820};
RN   [1] {ECO:0000313|EMBL:EAT47316.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Liverpool {ECO:0000313|EMBL:EAT47316.1};
RA   Loftus B.J., Nene V.M., Hannick L.I., Bidwell S., Haas B., Amedeo P.,
RA   Orvis J., Wortman J.R., White O.R., Salzberg S., Shumway M., Koo H.,
RA   Zhao Y., Holmes M., Miller J., Schatz M., Pop M., Pai G.,
RA   Utterback T., Rogers Y.-H., Kravitz S., Fraser C.M.;
RL   Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:EAT47316.1, ECO:0000313|Proteomes:UP000008820, ECO:0000313|VectorBase:AAEL001567-PA}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Liverpool {ECO:0000313|EMBL:EAT47316.1}, and Liverpool/LVPib12
RC   {ECO:0000313|Proteomes:UP000008820,
RC   ECO:0000313|VectorBase:AAEL001567-PA};
RX   PubMed=17510324; DOI=10.1126/science.1138878;
RA   Nene V., Wortman J.R., Lawson D., Haas B.J., Kodira C.D., Tu Z.J.,
RA   Loftus B.J., Xi Z., Megy K., Grabherr M., Ren Q., Zdobnov E.M.,
RA   Lobo N.F., Campbell K.S., Brown S.E., Bonaldo M.F., Zhu J.,
RA   Sinkins S.P., Hogenkamp D.G., Amedeo P., Arensburger P.,
RA   Atkinson P.W., Bidwell S.L., Biedler J., Birney E., Bruggner R.V.,
RA   Costas J., Coy M.R., Crabtree J., Crawford M., DeBruyn B.,
RA   DeCaprio D., Eiglmeier K., Eisenstadt E., El-Dorry H., Gelbart W.M.,
RA   Gomes S.L., Hammond M., Hannick L.I., Hogan J.R., Holmes M.H.,
RA   Jaffe D., Johnston S.J., Kennedy R.C., Koo H., Kravitz S.,
RA   Kriventseva E.V., Kulp D., Labutti K., Lee E., Li S., Lovin D.D.,
RA   Mao C., Mauceli E., Menck C.F., Miller J.R., Montgomery P., Mori A.,
RA   Nascimento A.L., Naveira H.F., Nusbaum C., O'Leary S.B., Orvis J.,
RA   Pertea M., Quesneville H., Reidenbach K.R., Rogers Y.-H.C., Roth C.W.,
RA   Schneider J.R., Schatz M., Shumway M., Stanke M., Stinson E.O.,
RA   Tubio J.M.C., Vanzee J.P., Verjovski-Almeida S., Werner D.,
RA   White O.R., Wyder S., Zeng Q., Zhao Q., Zhao Y., Hill C.A.,
RA   Raikhel A.S., Soares M.B., Knudson D.L., Lee N.H., Galagan J.,
RA   Salzberg S.L., Paulsen I.T., Dimopoulos G., Collins F.H., Bruce B.,
RA   Fraser-Liggett C.M., Severson D.W.;
RT   "Genome sequence of Aedes aegypti, a major arbovirus vector.";
RL   Science 316:1718-1723(2007).
RN   [3] {ECO:0000313|EMBL:EAT47316.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Liverpool {ECO:0000313|EMBL:EAT47316.1};
RG   VectorBase;
RL   Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
RN   [4] {ECO:0000313|VectorBase:AAEL001567-PA}
RP   IDENTIFICATION.
RC   STRAIN=Liverpool/LVPib12 {ECO:0000313|VectorBase:AAEL001567-PA};
RG   VectorBase;
RL   Submitted (FEB-2017) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-
CC       ProRule:PRU00251, ECO:0000256|SAAS:SAAS00579852}.
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DR   EMBL; CH477221; EAT47316.1; -; Genomic_DNA.
DR   RefSeq; XP_001653578.1; XM_001653528.1.
DR   UniGene; Aae.7359; -.
DR   ProteinModelPortal; Q17KU1; -.
DR   STRING; 7159.AAEL001567-PA; -.
DR   EnsemblMetazoa; AAEL001567-RA; AAEL001567-PA; AAEL001567.
DR   KEGG; aag:AaeL_AAEL001567; -.
DR   VectorBase; AAEL001567-RA; AAEL001567-PA; AAEL001567.
DR   eggNOG; KOG0014; Eukaryota.
DR   eggNOG; COG5068; LUCA.
DR   HOGENOM; HOG000230620; -.
DR   InParanoid; Q17KU1; -.
DR   KO; K09260; -.
DR   OMA; HLVMPNS; -.
DR   OrthoDB; EOG091G0F9N; -.
DR   PhylomeDB; Q17KU1; -.
DR   Proteomes; UP000008820; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   GO; GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   CDD; cd00265; MADS_MEF2_like; 1.
DR   Gene3D; 3.40.1810.10; -; 1.
DR   InterPro; IPR022102; HJURP_C.
DR   InterPro; IPR033896; MADS_MEF2-like.
DR   InterPro; IPR002100; TF_MADSbox.
DR   Pfam; PF12347; HJURP_C; 1.
DR   Pfam; PF00319; SRF-TF; 1.
DR   PRINTS; PR00404; MADSDOMAIN.
DR   SMART; SM00432; MADS; 1.
DR   SUPFAM; SSF55455; SSF55455; 1.
DR   PROSITE; PS00350; MADS_BOX_1; 1.
DR   PROSITE; PS50066; MADS_BOX_2; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000008820};
KW   DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00251,
KW   ECO:0000256|SAAS:SAAS00579830};
KW   Nucleus {ECO:0000256|PROSITE-ProRule:PRU00251,
KW   ECO:0000256|SAAS:SAAS00579820};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008820};
KW   Transcription {ECO:0000256|PROSITE-ProRule:PRU00251,
KW   ECO:0000256|SAAS:SAAS00579841};
KW   Transcription regulation {ECO:0000256|PROSITE-ProRule:PRU00251,
KW   ECO:0000256|SAAS:SAAS00579844}.
FT   DOMAIN        1     61       MADS-box. {ECO:0000259|PROSITE:PS50066}.
SQ   SEQUENCE   495 AA;  52422 MW;  E55E9888C1EAF34C CRC64;
     MGRKKIQISR ITDERNRQVT FNKRKFGVMK KAYELSVLCD CEIALIIFSS TNKLYQYAST
     DMDKVLLKYT EYNEPHESLT NKNIIEKENK NGTMSPDSPE PEDSYTLTPR TEAKYNKIDE
     DFQIMMQRNQ QLSASGRVNM AGNSYSLPVS VPVIGTYNDS SMMQSSPQMA HNSISPRPSS
     SETDSVYPSG GILEMSNGYP HSASPLGGSP SPGPSPVQHQ TIKQGSPGSS NGRSSNLRVV
     IPTPMNPTIN TDDLSYVEHS RQQSSNLNTP VVALQTPIPG LSNYTTTLGS FGAQDFSINS
     DLSMIASWGA AASNAHAQNA MNSLGQHSSS GLPHLAVPNS TPPPSTSPLT VKIKAEPISP
     PREHQSSSHH HHHHSNLSGS GGGGGGGGGP GGSGGANGQQ NNNQLTVTSM AQVGGHSNSQ
     SVALGSSLNH SHLIHSRPSS TGHLTPTPGS VTPTNAPSPV DIRHLGGGGP LPDYDSPVGA
     SNAHKRPRIS EGWAT
//
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