GenomeNet

Database: UniProt/TrEMBL
Entry: Q1CTP1_HELPH
LinkDB: Q1CTP1_HELPH
Original site: Q1CTP1_HELPH 
ID   Q1CTP1_HELPH            Unreviewed;       384 AA.
AC   Q1CTP1;
DT   11-JUL-2006, integrated into UniProtKB/TrEMBL.
DT   11-JUL-2006, sequence version 1.
DT   11-DEC-2013, entry version 55.
DE   SubName: Full=Quinone-reactive Ni/Fe hydrogenase HydA;
DE            EC=1.12.5.1;
GN   OrderedLocusNames=HPAG1_0614;
OS   Helicobacter pylori (strain HPAG1).
OC   Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=357544;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HPAG1;
RX   PubMed=16788065; DOI=10.1073/pnas.0603784103;
RA   Oh J.D., Kling-Baeckhed H., Giannakis M., Xu J., Fulton R.S.,
RA   Fulton L.A., Cordum H.S., Wang C., Elliott G., Edwards J.,
RA   Mardis E.R., Engstrand L.G., Gordon J.I.;
RT   "The complete genome sequence of a chronic atrophic gastritis
RT   Helicobacter pylori strain: evolution during disease progression.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:9999-10004(2006).
CC   -!- COFACTOR: Binds 1 3Fe-4S cluster (By similarity).
CC   -!- COFACTOR: Binds 2 4Fe-4S clusters (By similarity).
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; CP000241; ABF84681.1; -; Genomic_DNA.
DR   RefSeq; YP_627355.1; NC_008086.1.
DR   ProteinModelPortal; Q1CTP1; -.
DR   STRING; 357544.HPAG1_0614; -.
DR   EnsemblBacteria; ABF84681; ABF84681; HPAG1_0614.
DR   GeneID; 4098857; -.
DR   KEGG; hpa:HPAG1_0614; -.
DR   PATRIC; 20602576; VBIHelPyl56048_0636.
DR   eggNOG; COG1740; -.
DR   HOGENOM; HOG000278822; -.
DR   KO; K05927; -.
DR   OMA; QAEENKH; -.
DR   OrthoDB; EOG6J74S9; -.
DR   ProtClustDB; CLSK872400; -.
DR   BioCyc; HPYL357544:GH1F-624-MONOMER; -.
DR   GO; GO:0009375; C:ferredoxin hydrogenase complex; IEA:InterPro.
DR   GO; GO:0051538; F:3 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0008901; F:ferredoxin hydrogenase activity; IEA:InterPro.
DR   GO; GO:0047067; F:hydrogen:quinone oxidoreductase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.700; -; 1.
DR   Gene3D; 4.10.480.10; -; 1.
DR   InterPro; IPR027394; Cytochrome-c3_hydrogenase_C.
DR   InterPro; IPR006137; NADH_UbQ_OxRdtase-like_20kDa.
DR   InterPro; IPR001821; NiFe_hydrogenase_ssu.
DR   InterPro; IPR006311; TAT_signal.
DR   Pfam; PF01058; Oxidored_q6; 1.
DR   PIRSF; PIRSF000310; NiFe_hyd_ssu; 1.
DR   PRINTS; PR00614; NIHGNASESMLL.
DR   TIGRFAMs; TIGR00391; hydA; 1.
DR   PROSITE; PS51318; TAT; 1.
PE   3: Inferred from homology;
KW   3Fe-4S; 4Fe-4S; Complete proteome; Iron; Iron-sulfur; Metal-binding;
KW   Oxidoreductase.
FT   METAL        86     86       Iron-sulfur 1 (4Fe-4S) (By similarity).
FT   METAL        89     89       Iron-sulfur 1 (4Fe-4S) (By similarity).
FT   METAL       185    185       Iron-sulfur 1 (4Fe-4S) (By similarity).
FT   METAL       218    218       Iron-sulfur 1 (4Fe-4S) (By similarity).
FT   METAL       256    256       Iron-sulfur 2 (4Fe-4S); via pros nitrogen
FT                                (By similarity).
FT   METAL       259    259       Iron-sulfur 2 (4Fe-4S) (By similarity).
FT   METAL       284    284       Iron-sulfur 2 (4Fe-4S) (By similarity).
FT   METAL       290    290       Iron-sulfur 2 (4Fe-4S) (By similarity).
FT   METAL       299    299       Iron-sulfur 3 (3Fe-4S) (By similarity).
FT   METAL       318    318       Iron-sulfur 3 (3Fe-4S) (By similarity).
FT   METAL       321    321       Iron-sulfur 3 (3Fe-4S) (By similarity).
SQ   SEQUENCE   384 AA;  42255 MW;  C52765253A07D315 CRC64;
     MFYDEKKTYQ KIEERLDIVS SFNAHNEHKN LQDEFKGAGI SRRDLLKWAG MMSAALALPA
     SFAPLTLKAV EVANRLPVIW LHMAECTGCS ESLLRSADPT IDSIIFDYIN LEYHETIMVA
     SGFQAEKSLH DAIEKHKNNY ILMVEGGIPQ GTEYFLTQGP NAETGAEECR KAAQYAAAIF
     AIGTCSSFGG VQAAYPNPSN AQPLHKIIDK PVINVPGCPP SEKNIVGNVL YYLMFGALPK
     LDAYNRPSWA YGNRIHDLCE RRGHFDAGEF VEHFGDENAK RGFCLYKMGC KGPYTFNNCS
     KLRFNSHTSW PIGAGHGCIG CSEPNFWDTM SPFEEPLANR SIKTAFDGLG ADKVADKVGT
     TLLSATAIGI VAHALLSKAI KNKE
//
DBGET integrated database retrieval system