ID Q1CTP1_HELPH Unreviewed; 384 AA.
AC Q1CTP1;
DT 11-JUL-2006, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2006, sequence version 1.
DT 01-MAY-2013, entry version 51.
DE SubName: Full=Quinone-reactive Ni/Fe hydrogenase HydA;
DE EC=1.12.5.1;
GN OrderedLocusNames=HPAG1_0614;
OS Helicobacter pylori (strain HPAG1).
OC Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=357544;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HPAG1;
RX PubMed=16788065; DOI=10.1073/pnas.0603784103;
RA Oh J.D., Kling-Backhed H., Giannakis M., Xu J., Fulton R.S.,
RA Fulton L.A., Cordum H.S., Wang C., Elliott G., Edwards J.,
RA Mardis E.R., Engstrand L.G., Gordon J.I.;
RT "The complete genome sequence of a chronic atrophic gastritis
RT Helicobacter pylori strain: evolution during disease progression.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:9999-10004(2006).
CC -!- COFACTOR: Binds 1 3Fe-4S cluster (By similarity).
CC -!- COFACTOR: Binds 2 4Fe-4S clusters (By similarity).
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DR EMBL; CP000241; ABF84681.1; -; Genomic_DNA.
DR RefSeq; YP_627355.1; NC_008086.1.
DR ProteinModelPortal; Q1CTP1; -.
DR STRING; 357544.HPAG1_0614; -.
DR EnsemblBacteria; ABF84681; ABF84681; HPAG1_0614.
DR GeneID; 4098857; -.
DR KEGG; hpa:HPAG1_0614; -.
DR PATRIC; 20602576; VBIHelPyl56048_0636.
DR eggNOG; COG1740; -.
DR HOGENOM; HOG000278822; -.
DR KO; K05927; -.
DR OMA; TLEFCDV; -.
DR ProtClustDB; CLSK872400; -.
DR BioCyc; HPYL357544:GH1F-656-MONOMER; -.
DR GO; GO:0009375; C:ferredoxin hydrogenase complex; IEA:InterPro.
DR GO; GO:0051538; F:3 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0008901; F:ferredoxin hydrogenase activity; IEA:InterPro.
DR GO; GO:0047067; F:hydrogen:quinone oxidoreductase activity; IEA:EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR GO; GO:0048038; F:quinone binding; IEA:InterPro.
DR Gene3D; 3.40.50.700; -; 1.
DR InterPro; IPR006137; NADH_UbQ_OxRdtase-like_20kDa.
DR InterPro; IPR001821; NiFe_hydrogenase_ssu.
DR InterPro; IPR006311; TAT_signal.
DR Pfam; PF01058; Oxidored_q6; 1.
DR PIRSF; PIRSF000310; NiFe_hyd_ssu; 1.
DR PRINTS; PR00614; NIHGNASESMLL.
DR TIGRFAMs; TIGR00391; hydA; 1.
DR PROSITE; PS51318; TAT; 1.
PE 3: Inferred from homology;
KW 3Fe-4S; 4Fe-4S; Complete proteome; Iron; Iron-sulfur; Metal-binding;
KW Oxidoreductase.
FT METAL 86 86 Iron-sulfur 1 (4Fe-4S) (By similarity).
FT METAL 89 89 Iron-sulfur 1 (4Fe-4S) (By similarity).
FT METAL 185 185 Iron-sulfur 1 (4Fe-4S) (By similarity).
FT METAL 218 218 Iron-sulfur 1 (4Fe-4S) (By similarity).
FT METAL 256 256 Iron-sulfur 2 (4Fe-4S); via pros nitrogen
FT (By similarity).
FT METAL 259 259 Iron-sulfur 2 (4Fe-4S) (By similarity).
FT METAL 284 284 Iron-sulfur 2 (4Fe-4S) (By similarity).
FT METAL 290 290 Iron-sulfur 2 (4Fe-4S) (By similarity).
FT METAL 299 299 Iron-sulfur 3 (3Fe-4S) (By similarity).
FT METAL 318 318 Iron-sulfur 3 (3Fe-4S) (By similarity).
FT METAL 321 321 Iron-sulfur 3 (3Fe-4S) (By similarity).
SQ SEQUENCE 384 AA; 42255 MW; C52765253A07D315 CRC64;
MFYDEKKTYQ KIEERLDIVS SFNAHNEHKN LQDEFKGAGI SRRDLLKWAG MMSAALALPA
SFAPLTLKAV EVANRLPVIW LHMAECTGCS ESLLRSADPT IDSIIFDYIN LEYHETIMVA
SGFQAEKSLH DAIEKHKNNY ILMVEGGIPQ GTEYFLTQGP NAETGAEECR KAAQYAAAIF
AIGTCSSFGG VQAAYPNPSN AQPLHKIIDK PVINVPGCPP SEKNIVGNVL YYLMFGALPK
LDAYNRPSWA YGNRIHDLCE RRGHFDAGEF VEHFGDENAK RGFCLYKMGC KGPYTFNNCS
KLRFNSHTSW PIGAGHGCIG CSEPNFWDTM SPFEEPLANR SIKTAFDGLG ADKVADKVGT
TLLSATAIGI VAHALLSKAI KNKE
//
