GenomeNet

Database: UniProt/TrEMBL
Entry: Q1ECX3_DANRE
LinkDB: Q1ECX3_DANRE
Original site: Q1ECX3_DANRE 
ID   Q1ECX3_DANRE            Unreviewed;       679 AA.
AC   Q1ECX3; F1R7N2;
DT   11-JUL-2006, integrated into UniProtKB/TrEMBL.
DT   11-JUL-2006, sequence version 1.
DT   22-NOV-2017, entry version 85.
DE   SubName: Full=Tgm2b protein {ECO:0000313|EMBL:AAI17636.1};
DE   SubName: Full=Transglutaminase 2b {ECO:0000313|Ensembl:ENSDARP00000099554};
GN   Name=tgm2b {ECO:0000313|EMBL:AAI17636.1,
GN   ECO:0000313|Ensembl:ENSDARP00000099554,
GN   ECO:0000313|ZFIN:ZDB-GENE-030131-2576};
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Cyprinidae; Danio.
OX   NCBI_TaxID=7955 {ECO:0000313|EMBL:AAI17636.1};
RN   [1] {ECO:0000313|EMBL:AAI17636.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Whole {ECO:0000313|EMBL:AAI17636.1};
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSDARP00000099554}
RP   IDENTIFICATION.
RC   STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000099554};
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
RN   [3] {ECO:0000313|Ensembl:ENSDARP00000099554, ECO:0000313|Proteomes:UP000000437}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000099554,
RC   ECO:0000313|Proteomes:UP000000437};
RX   PubMed=23594743; DOI=10.1038/nature12111;
RA   Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C.,
RA   Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L.,
RA   McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C.,
RA   Koch R., Rauch G.J., White S., Chow W., Kilian B., Quintais L.T.,
RA   Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T.,
RA   Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F.,
RA   Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H.,
RA   Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA   Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA   Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA   Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA   Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J.,
RA   Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P.,
RA   Barker N., Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G.,
RA   Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D.,
RA   Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K.,
RA   Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C.,
RA   Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J.,
RA   Murnane C., Gray E., Humphries M., Sycamore N., Barker D.,
RA   Saunders D., Wallis J., Babbage A., Hammond S.,
RA   Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A.,
RA   Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA   Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA   Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D.,
RA   Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z.,
RA   Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J.,
RA   Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C.,
RA   Raddatz G., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C.,
RA   Yang F., Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J.,
RA   Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C.,
RA   Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H.,
RA   Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J.,
RA   Stemple D.L.;
RT   "The zebrafish reference genome sequence and its relationship to the
RT   human genome.";
RL   Nature 496:498-503(2013).
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; CABZ01052101; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CABZ01052102; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CU571379; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CU634004; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BC117635; AAI17636.1; -; mRNA.
DR   RefSeq; NP_997821.2; NM_212656.2.
DR   UniGene; Dr.16524; -.
DR   STRING; 7955.ENSDARP00000099554; -.
DR   PaxDb; Q1ECX3; -.
DR   Ensembl; ENSDART00000114314; ENSDARP00000099554; ENSDARG00000074094.
DR   GeneID; 323856; -.
DR   CTD; 323856; -.
DR   ZFIN; ZDB-GENE-030131-2576; tgm2b.
DR   eggNOG; ENOG410IFMV; Eukaryota.
DR   eggNOG; ENOG410XQEZ; LUCA.
DR   GeneTree; ENSGT00760000119108; -.
DR   HOGENOM; HOG000231695; -.
DR   HOVERGEN; HBG004342; -.
DR   OMA; AHITNNT; -.
DR   OrthoDB; EOG091G030K; -.
DR   TreeFam; TF324278; -.
DR   Proteomes; UP000000437; Chromosome 6.
DR   Bgee; ENSDARG00000074094; -.
DR   GO; GO:0003810; F:protein-glutamine gamma-glutamyltransferase activity; IEA:InterPro.
DR   GO; GO:0018149; P:peptide cross-linking; IEA:InterPro.
DR   Gene3D; 2.60.40.10; -; 3.
DR   Gene3D; 3.90.260.10; -; 1.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR002931; Transglutaminase-like.
DR   InterPro; IPR036985; Transglutaminase-like_sf.
DR   InterPro; IPR023608; Transglutaminase_animal.
DR   InterPro; IPR008958; Transglutaminase_C.
DR   InterPro; IPR036238; Transglutaminase_C_sf.
DR   InterPro; IPR001102; Transglutaminase_N.
DR   Pfam; PF00927; Transglut_C; 2.
DR   Pfam; PF01841; Transglut_core; 1.
DR   Pfam; PF00868; Transglut_N; 1.
DR   PIRSF; PIRSF000459; TGM_EBP42; 1.
DR   SMART; SM00460; TGc; 1.
DR   SUPFAM; SSF49309; SSF49309; 2.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000000437};
KW   Proteomics identification {ECO:0000213|PeptideAtlas:Q1ECX3};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000437}.
FT   DOMAIN      260    353       TGc. {ECO:0000259|SMART:SM00460}.
FT   ACT_SITE    268    268       {ECO:0000256|PIRSR:PIRSR000459-1}.
FT   ACT_SITE    327    327       {ECO:0000256|PIRSR:PIRSR000459-1}.
FT   ACT_SITE    350    350       {ECO:0000256|PIRSR:PIRSR000459-1}.
SQ   SEQUENCE   679 AA;  75773 MW;  CA43F4888970F033 CRC64;
     MALDIGSWDL ACKFNNTDHH TELNGTDRLI VRRGQAFTIN LQLNSGSYQP GYSQINITAE
     TGPDPQQQYG TRAVFSLSSE VDSSCWSAAV SSPPGESVCL SICAAPDAPI GHYTLTLDER
     IQIQFILLFN PWCPLDVVYM DNEEKLAEYV LAQDGIIFRG DAGYPVPLAW NFGQFEEGIL
     DACFRILDMN PKHRRNPAKD CSGRRNVIYV TRVLSAMINS NDQDSGVLEG CWRDTFDGGV
     SPMSWGGSVQ ILRTWDRSSC LPVRYGQCWV FAAVACTVAR AVGIPCRVVT NYYSAHDTNS
     NLLIERYVNE KGEVDHSSTR DMIWNYHCWV ESWMGRSDLP PGFDGWQASD PTPQEKSEGV
     FCCGPVPVRA IKEGELTFKY DAPFVFAEVN ADLVYFLKSK DGSTRKINYD QKVGQKISTK
     SVGRDEREDI THLYKYPEGS ADERRVFEKA NHQNKLLQEK QNTGLNITIK LSSGVRKGCD
     FDVFAIVTNG TAEEKKCRLV FASRAVSYNG VIGRECGFKD LLNVELPPGG ERKVPLRLNY
     SKYCNNLTED NLIRLGALLI DYSTRDAIMA MRDIVLDDPE IKIRILGEPK ENRKLAAELT
     IQNPLPEALQ SCCFTIEGAN LTGGDSITHT LDSSIEPGQE AKAKIYFTPT QSGLRKLLVD
     FNSDKLGHVR GYRNVIIGK
//
DBGET integrated database retrieval system