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Database: UniProt/TrEMBL
Entry: Q1MRH0_LAWIP
LinkDB: Q1MRH0_LAWIP
Original site: Q1MRH0_LAWIP 
ID   Q1MRH0_LAWIP            Unreviewed;       254 AA.
AC   Q1MRH0;
DT   30-MAY-2006, integrated into UniProtKB/TrEMBL.
DT   30-MAY-2006, sequence version 1.
DT   19-FEB-2014, entry version 58.
DE   RecName: Full=Enoyl-[acyl-carrier-protein] reductase [NADH];
DE            EC=1.3.1.9;
GN   Name=fabI; OrderedLocusNames=LI0350;
OS   Lawsonia intracellularis (strain PHE/MN1-00).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Desulfovibrionales;
OC   Desulfovibrionaceae; Lawsonia.
OX   NCBI_TaxID=363253;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PHE/MN1-00;
RA   Kaur K., Zhang Q., Beckler D., Munir S., Li L., Kinsley K., Herron L.,
RA   Peterson A., May B., Singh S., Gebhart C., Kapur V.;
RT   "The complete genome sequence of Lawsonia intracellularis: the
RT   causative agent of proliferative enteropathy.";
RL   Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: An acyl-[acyl-carrier protein] + NAD(+) = a
CC       trans-2,3-dehydroacyl-[acyl-carrier protein] + NADH.
CC   -!- PATHWAY: Lipid metabolism; fatty acid biosynthesis.
CC   -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases
CC       (SDR) family. FabI subfamily.
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DR   EMBL; AM180252; CAJ54406.1; -; Genomic_DNA.
DR   RefSeq; YP_594727.1; NC_008011.1.
DR   ProteinModelPortal; Q1MRH0; -.
DR   SMR; Q1MRH0; 2-253.
DR   STRING; 363253.LI0350; -.
DR   GeneID; 4059306; -.
DR   KEGG; lip:LI0350; -.
DR   PATRIC; 22304089; VBILawInt40445_0389.
DR   eggNOG; COG0623; -.
DR   KO; K00208; -.
DR   OMA; DCDVGSD; -.
DR   OrthoDB; EOG6HF644; -.
DR   ProtClustDB; CLSK2777755; -.
DR   BioCyc; LINT363253:GH6E-360-MONOMER; -.
DR   UniPathway; UPA00094; -.
DR   GO; GO:0004318; F:enoyl-[acyl-carrier-protein] reductase (NADH) activity; IEA:UniProtKB-EC.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.40.50.720; -; 1.
DR   InterPro; IPR014358; Enoyl-ACP_Rdtase_NADH.
DR   InterPro; IPR002347; Glc/ribitol_DH.
DR   InterPro; IPR016040; NAD(P)-bd_dom.
DR   PIRSF; PIRSF000094; Enoyl-ACP_rdct; 1.
DR   PRINTS; PR00081; GDHRDH.
PE   3: Inferred from homology;
KW   Complete proteome; Fatty acid biosynthesis; Fatty acid metabolism;
KW   Lipid biosynthesis; Lipid metabolism; NAD; Oxidoreductase.
FT   ACT_SITE    144    144       Proton acceptor (By similarity).
FT   ACT_SITE    154    154       Proton acceptor (By similarity).
FT   BINDING      94     94       Substrate; via amide nitrogen and
FT                                carbonyl oxygen (By similarity).
SQ   SEQUENCE   254 AA;  27963 MW;  274F74E00A855336 CRC64;
     MLLKNKKCLI LGIANNKSIA YGIASSFKEH GAKLAFNYVN DAIQKRVEPI SQELNGDFIF
     QCDVSKDDEI KEAVKLVQKE WGHIDVLVHS VAFANREDLT KRFIETSRDG FHLALDISTY
     SLITLCHAFE PLFVHGSSVL TMTYYGAQKV IPHYNVMGVA KAALESSVRY LSVELGEKNI
     RINAISAGPI KTLAASGISD FKKIFNHIEE HSPLKRNVTI EDVGKSAVFL ASDLSSGVTG
     EILFVDAGYN NLGI
//
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