ID Q2FHH7_STAA3 Unreviewed; 260 AA.
AC Q2FHH7;
DT 21-MAR-2006, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2006, sequence version 1.
DT 01-MAY-2013, entry version 50.
DE RecName: Full=Phosphatidate cytidylyltransferase;
DE EC=2.7.7.41;
GN Name=cdsA; OrderedLocusNames=SAUSA300_1154;
OS Staphylococcus aureus (strain USA300).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcus.
OX NCBI_TaxID=367830;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=USA300;
RX PubMed=16517273; DOI=10.1016/S0140-6736(06)68231-7;
RA Diep B.A., Gill S.R., Chang R.F., Phan T.H., Chen J.H., Davidson M.G.,
RA Lin F., Lin J., Carleton H.A., Mongodin E.F., Sensabaugh G.F.,
RA Perdreau-Remington F.;
RT "Complete genome sequence of USA300, an epidemic clone of community-
RT acquired meticillin-resistant Staphylococcus aureus.";
RL Lancet 367:731-739(2006).
CC -!- CATALYTIC ACTIVITY: CTP + phosphatidate = diphosphate + CDP-
CC diacylglycerol.
CC -!- PATHWAY: Phospholipid metabolism; CDP-diacylglycerol biosynthesis;
CC CDP-diacylglycerol from sn-glycerol 3-phosphate: step 3/3.
CC -!- SIMILARITY: Belongs to the CDS family.
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DR EMBL; CP000255; ABD21341.1; -; Genomic_DNA.
DR RefSeq; YP_493851.1; NC_007793.1.
DR STRING; 451515.SAUSA300_1154; -.
DR EnsemblBacteria; ABD21341; ABD21341; SAUSA300_1154.
DR GeneID; 3913399; -.
DR KEGG; saa:SAUSA300_1154; -.
DR PATRIC; 19591677; VBIStaAur129981_1266.
DR HOGENOM; HOG000006169; -.
DR KO; K00981; -.
DR OMA; TWTVLSK; -.
DR ProtClustDB; CLSK885236; -.
DR BioCyc; SAUR451515:GH3C-1207-MONOMER; -.
DR UniPathway; UPA00557; UER00614.
DR GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR GO; GO:0004605; F:phosphatidate cytidylyltransferase activity; IEA:EC.
DR GO; GO:0016024; P:CDP-diacylglycerol biosynthetic process; IEA:UniProtKB-UniPathway.
DR InterPro; IPR000374; PC_trans.
DR Pfam; PF01148; CTP_transf_1; 1.
DR PROSITE; PS01315; CDS; 1.
PE 3: Inferred from homology;
KW Complete proteome; Nucleotidyltransferase; Transferase; Transmembrane.
SQ SEQUENCE 260 AA; 28964 MW; 02C2727C3801C694 CRC64;
MKVRTLTAII ALIVFLPILL KGGLVLMIFA NILALIALKE LLNMNMIKFV SVPGLISAVG
LIIIMLPQHA GPWVQVIQLK SLIAMSFIVL SYTVLSKNRF SFMDAAFCLM SVAYVGIGFM
FFYETRSEGL HYILYAFLIV WLTDTGAYLF GKMMGKHKLW PVISPNKTIE GFIGGLFCSL
IVPLAMLYFV DFNMNVWILL GVTLILSLFG QLGDLVESGF KRHFGVKDSG RILPGHGGIL
DRFDSFMFVL PLLNILLIQS
//
