ID Q2T4F2_BURTA Unreviewed; 465 AA.
AC Q2T4F2;
DT 24-JAN-2006, integrated into UniProtKB/TrEMBL.
DT 24-JAN-2006, sequence version 1.
DT 27-MAR-2024, entry version 92.
DE SubName: Full=Drug resistance transporter, EmrB/QacA family {ECO:0000313|EMBL:ABC35870.1};
GN OrderedLocusNames=BTH_II1753 {ECO:0000313|EMBL:ABC35870.1};
OS Burkholderia thailandensis (strain ATCC 700388 / DSM 13276 / CCUG 48851 /
OS CIP 106301 / E264).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia; pseudomallei group.
OX NCBI_TaxID=271848 {ECO:0000313|EMBL:ABC35870.1, ECO:0000313|Proteomes:UP000001930};
RN [1] {ECO:0000313|EMBL:ABC35870.1, ECO:0000313|Proteomes:UP000001930}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700388 / DSM 13276 / CIP 106301 / E264
RC {ECO:0000313|Proteomes:UP000001930};
RX PubMed=16336651; DOI=10.1186/1471-2164-6-174;
RA Kim H.S., Schell M.A., Yu Y., Ulrich R.L., Sarria S.H., Nierman W.C.,
RA DeShazer D.;
RT "Bacterial genome adaptation to niches: divergence of the potential
RT virulence genes in three Burkholderia species of different survival
RT strategies.";
RL BMC Genomics 6:174-174(2005).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP000085; ABC35870.1; -; Genomic_DNA.
DR RefSeq; WP_009897814.1; NZ_CP008786.1.
DR AlphaFoldDB; Q2T4F2; -.
DR KEGG; bte:BTH_II1753; -.
DR HOGENOM; CLU_000960_28_0_4; -.
DR Proteomes; UP000001930; Chromosome II.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR Gene3D; 1.20.1720.10; Multidrug resistance protein D; 1.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR42718; MAJOR FACILITATOR SUPERFAMILY MULTIDRUG TRANSPORTER MFSC; 1.
DR PANTHER; PTHR42718:SF9; METHYL VIOLOGEN RESISTANCE PROTEIN SMVA; 1.
DR Pfam; PF07690; MFS_1; 1.
DR PRINTS; PR01036; TCRTETB.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 10..456
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
SQ SEQUENCE 465 AA; 49161 MW; 8F3ACC6101155B77 CRC64;
MPSAIYAFIA PLIVACALFM ESVDANIIVT ALPAMARDFG QNPVTLNIAI TSYVVGLGVF
IPICGWLADR FGARTVFRTA IGIFVAGSLL CAASNNLELF TFARFVQGVG GAMMVPVGRI
IIFRAVPRSE LVRAMNYLSV PALFGPAAGP LLGGFITTYL HWRLIFFINV PIGILGIYLA
NKHIANTHEL DPGPLDWFGF VLSAAGAALL LMGLTLLDGA LVTRGAALAM GATGAALLGG
YVLYARRVER PVLDLRFLRI PTYHASVVGG SLFRIGLGAV PFLLPLALQE GLGMSAFHSG
AITCASAVGG AFTRLLAPRT LKRFGFRTVL MYNAAFAGLA IAAYGVFHPG MPTLAIWLIV
LVGGVFPALQ FTSLNSMIYA EIASRDAGRA TSLGSVVQQM SLGLGVTVAA LVLHVSHWAQ
GHPTMVWSDF WPAFVVVGLC SFASIPITRR LPPNAGDEVA RGKRG
//
