ID Q2YXM0_STAAB Unreviewed; 302 AA.
AC Q2YXM0;
DT 20-DEC-2005, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2005, sequence version 1.
DT 01-MAY-2013, entry version 59.
DE RecName: Full=Succinyl-CoA ligase [ADP-forming] subunit alpha;
DE EC=6.2.1.5;
GN OrderedLocusNames=SAB1110;
OS Staphylococcus aureus (strain bovine RF122 / ET3-1).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcus.
OX NCBI_TaxID=273036;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=bovine RF122 / ET3-1;
RX PubMed=17971880; DOI=10.1371/journal.pone.0001120;
RA Herron-Olson L., Fitzgerald J.R., Musser J.M., Kapur V.;
RT "Molecular correlates of host specialization in Staphylococcus
RT aureus.";
RL PLoS ONE 2:E1120-E1120(2007).
CC -!- CATALYTIC ACTIVITY: ATP + succinate + CoA = ADP + phosphate +
CC succinyl-CoA.
CC -!- SUBUNIT: Heterotetramer of two alpha and two beta subunits (By
CC similarity).
CC -!- SIMILARITY: Belongs to the succinate/malate CoA ligase alpha
CC subunit family.
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DR EMBL; AJ938182; CAI80799.1; -; Genomic_DNA.
DR RefSeq; YP_416590.1; NC_007622.1.
DR ProteinModelPortal; Q2YXM0; -.
DR SMR; Q2YXM0; 2-284.
DR STRING; 273036.SAB1110; -.
DR EnsemblBacteria; CAI80799; CAI80799; SAB1110.
DR GeneID; 3795071; -.
DR KEGG; sab:SAB1110; -.
DR PATRIC; 19523067; VBIStaAur92441_1182.
DR eggNOG; COG0074; -.
DR HOGENOM; HOG000239685; -.
DR KO; K01902; -.
DR OMA; KGRKKPM; -.
DR ProtClustDB; PRK05678; -.
DR BioCyc; SAUR273036:GJVS-1132-MONOMER; -.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003878; F:ATP citrate synthase activity; IEA:InterPro.
DR GO; GO:0048037; F:cofactor binding; IEA:InterPro.
DR GO; GO:0004775; F:succinate-CoA ligase (ADP-forming) activity; IEA:EC.
DR Gene3D; 3.40.50.261; -; 1.
DR Gene3D; 3.40.50.720; -; 1.
DR InterPro; IPR017440; Cit_synth/succinyl-CoA_lig_AS.
DR InterPro; IPR003781; CoA-bd.
DR InterPro; IPR005810; CoA_lig_alpha.
DR InterPro; IPR005811; CoA_ligase.
DR InterPro; IPR016040; NAD(P)-bd_dom.
DR InterPro; IPR016102; Succinyl-CoA_synth-like.
DR Pfam; PF02629; CoA_binding; 1.
DR Pfam; PF00549; Ligase_CoA; 1.
DR PIRSF; PIRSF001553; SucCS_alpha; 1.
DR PRINTS; PR01798; SCOASYNTHASE.
DR SMART; SM00881; CoA_binding; 1.
DR SUPFAM; SSF52210; CoA_ligase; 1.
DR TIGRFAMs; TIGR01019; sucCoAalpha; 1.
DR PROSITE; PS01216; SUCCINYL_COA_LIG_1; 1.
DR PROSITE; PS00399; SUCCINYL_COA_LIG_2; 1.
PE 3: Inferred from homology;
KW ATP-binding; Complete proteome; Ligase; Nucleotide-binding;
KW Phosphoprotein.
FT ACT_SITE 247 247 Tele-phosphohistidine intermediate (By
FT similarity).
SQ SEQUENCE 302 AA; 31542 MW; C05AFD1B8DCC69E4 CRC64;
MSVFIDKNTK VMVQGITGST ALFHTKQMLD YGTKIVAGVT PGKGGQVVEG VPVFNTVEEA
KNETGATVSV IYVPAPFAAD SILEAADADL DMVICITEHI PVLDMVKVKR YLQGRKTRLV
GPNCPGVITA DECKIGIMPG YIHKKGHVGV VSRSGTLTYE AVHQLTEEGI GQTTAVGIGG
DPVNGTNFID VLKAFNEDDE TKAVVMIGEI GGTAEEEAAE WIKANMTKPV VGFIGGQTAP
PGKRMGHAGA IISGGKGTAE EKIKTLNSCG VKTAATPSEI GSTLIEAAKE AGIYESLLTV
NK
//
