ID   Q39P46_BURS3            Unreviewed;       564 AA.
AC   Q39P46;
DT   22-NOV-2005, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2005, sequence version 1.
DT   01-MAY-2013, entry version 51.
DE   SubName: Full=Acetolactate synthase, large subunit;
DE            EC=2.2.1.6;
GN   OrderedLocusNames=Bcep18194_C6721;
OS   Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760
OS   / NCIB 9086 / R18194)).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX   NCBI_TaxID=269483;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=383;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M.,
RA   Vergez L., Schmutz J., Larimer F., Land M., Kyrpides N., Lykidis A.,
RA   Richardson P.;
RT   "Complete sequence of chromosome 3 of Burkholderia sp. 383.";
RL   Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the TPP enzyme family.
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DR   EMBL; CP000150; ABB05770.1; -; Genomic_DNA.
DR   RefSeq; YP_366414.1; NC_007509.1.
DR   ProteinModelPortal; Q39P46; -.
DR   STRING; 269483.Bcep18194_C6721; -.
DR   EnsemblBacteria; ABB05770; ABB05770; Bcep18194_C6721.
DR   GeneID; 3733809; -.
DR   KEGG; bur:Bcep18194_C6721; -.
DR   PATRIC; 19281464; VBIBurSp120713_0191.
DR   eggNOG; COG0028; -.
DR   HOGENOM; HOG000258446; -.
DR   KO; K01652; -.
DR   OMA; ERAPAVC; -.
DR   ProtClustDB; PRK07524; -.
DR   BioCyc; BSP269483:GHLS-6805-MONOMER; -.
DR   GO; GO:0003984; F:acetolactate synthase activity; IEA:EC.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
DR   GO; GO:0008152; P:metabolic process; IEA:GOC.
DR   InterPro; IPR012000; Thiamin_PyroP_enz_cen_dom.
DR   InterPro; IPR012001; Thiamin_PyroP_enz_TPP-bd_dom.
DR   InterPro; IPR000399; TPP-bd_CS.
DR   InterPro; IPR011766; TPP_enzyme-bd_C.
DR   Pfam; PF02775; TPP_enzyme_C; 1.
DR   Pfam; PF00205; TPP_enzyme_M; 1.
DR   Pfam; PF02776; TPP_enzyme_N; 1.
DR   PROSITE; PS00187; TPP_ENZYMES; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Thiamine pyrophosphate; Transferase.
SQ   SEQUENCE   564 AA;  58456 MW;  E97B79E1BBDE9F7D CRC64;
     MNHPATVSSI AGARKATAAP CHARPRTCGE ALVDLLERHG VECVFGIPGV HTVELYRGLA
     ASSIRHVTPR HEQGAGFMAD GYARVTGRPG VCFIITGPGM TNIATAMAQA YADSIPMLVI
     SSVNARRELG SGDGRLHELP SQRDVFAGLT AFSHTLLDAA DLPQVLARAF AVFASARPRP
     VHIEIPLDVI VMPAPALSDA PPALPARPAP DANALAAAAD LLAHARRPLI LAGGGAIHAA
     AELRELAERL HAPVALTINA KGLLPAGHPL LIGSTQSLPA TRAAIRDADV VLAVGTELGE
     TDYDVTFDGG FAIDGRLIRI DIDAQQLMRN ARAEIAIAGD SQLALGALST RLHETPAPTP
     DAGWGAPRVA AVRAAIAATH DSAAQSQALL IDTIVATLPG AIIAGDSTSP VYVGNFTHDA
     PAPRSWFNSS TGYGTLGYGL PAAIGAKLAA PARPVVCLIG DGGLQFTLPE LASAVEARLP
     VIVIVWNNHG YGEIRKYMVA RDITPVGVDP YTPDFQVLAR GFGCAAHTAA TPGALAAALR
     DAAARAIPTV IEIDEATWFG QVQR
//